Academic Articles & Research Papers

Shear banding and flow instabilities in wormlike micelles: Modelling and mechanisms – A review

Worm-like micelles (WLMs) are dynamic, self-assembling supramolecular structures that exhibit complex viscoelastic behaviour due to their ability to undergo reversible scission, fusion, branching, and sequence rearrangement. This review pro...

Mechanical properties of gummies are associated with threat-related behavior and neuroglial markers in mice.

Image-based quantification of histological features as a function of spatial location using the Tissue Positioning SystemResearch in context

Summary: Background: Tissues such as the liver lobule, kidney nephron, and intestinal gland exhibit intricate patterns of zonated gene expression corresponding to distinct cell types and functions. To quantitatively understand zonation, it...

Development and validation of a predictive model for diabetic peripheral neuropathy with type 2 diabetes mellitus in Xinjiang, China

Abstract This study aims to identify risk factors associated with diabetic peripheral neuropathy (DPN) in patients with type 2 diabetesmellitus (T2DM) and to develop a predictive model to support clinical decision-making. A total of 1,001 p...

Disrupted cortex-wide dynamics impair motor planning in Shank3-mutant mice.

Machine learning in pain research

1. Introduction Pain and pain chronification are incompletely understood and unresolved medical problems that continue to have a high prevalence.14 It has been accepted that pain is a complex phenomenon.2,32,72 Contemporary methods of compu...

Prediction of Drug Targets for Specific Diseases Leveraging Gene Perturbation Data: A Machine Learning Approach

Identification of the correct targets is a key element for successful drug development. However, there are limited approaches for predicting drug targets for specific diseases using omics data, and few have leveraged expression profiles fro...

Multi-omics reveals the DR5-FXR-CHPT1 axis governs hepatocyte pyroptosis via glycerophospholipid remodeling after major partial hepatectomy in male mice.

Undertriage of geriatric trauma patients in the emergency department: A retrospective single-center study.

Cost-effective, open-source, automated apparatus for testing transitive inference in mice

Abstract Transitive inference is a form of reasoning that relies on prior knowledge and benefits survival in diverse species. While initially designed for humans, the transitive inference task has been adapted for mice, allowing for integra...