Academic Articles & Research Papers

Fundamental Immunology

The first great revolution in immunology is credited to Louis Pasteur. Among the many achievements stemming from that early period is the elimination of smallpox from the entire world in 1977, a century later. The second great revolution, b...

The Investigation of Impact of Complement Policy for Energy Price Policy Reform on Transport Sector in Iran by Computable General Equilibrium

With regard to the ever-increasing need for energy in current societies to satisfy various requirements, scientists and researchers from different countries, such as Iran, have a basic approach in their agenda to achieve renewable energies،...

Nano-enabled microbial bioinputs for sustainable agriculture: advances, mechanisms, applications, and future challenges

Microbial bioinputs have emerged as key components of sustainable agriculture owing to their ability to promote plant growth, improve nutrient acquisition, enhance tolerance to biotic and abiotic stresses, and suppress phytopathogens. Despi...

Composite-Decorative Tiles with Granite

The paper presents the results of the authors’ scientific research on a composite material with polymeric matrix, hardened with rock particles. It was studied the influence of the quantity of the hardening phase on the compression resistanc...

The significance of the Second Hague Peace conference in the development of the institution of peaceful settlement of international disputes

Background. Domestic diplomacy and international legal science played a leading role in the formation of the institution of peaceful resolution of international disputes. It was Russia that initiated two Hague Peace Conferences in 1899 and ...

Achieving high strength in 430 stainless steel by laser powder bed fusion: microstructure-property relationships and strengthening strategies

Conventional manufacturing of 430 ferritic stainless steel faces significant challenges, including severe work hardening, rapid tool wear, and limited strengthening via heat treatment. To overcome these limitations, this study employs laser...

Effect of the Temperature and Oxidation Time on Some Physicochemical Characteristics of the Rice Bran Oil

Due to their excellent characteristics, vegetable oils are successfully used in various formulations of organic lubricants. In this context, the advanced biodegradability and excellent lubricity performance of rice oil leads to its being co...

Active galactic nucleus activity in nearby disk galaxies: The roles of bar strength and spiral arm morphology

Context. The transport of gas toward galactic centers and its connection to active galactic nucleus (AGN) activity remain key open questions in galaxy evolution. In particular, the relative roles of stellar bars and spiral arms and their po...

Complex Riemannian Spacetime: Removal of Black Hole Singularities and Black Hole Paradoxes

An approach is presented to resolve key paradoxes in black hole physics through the application of complex Riemannian spacetime. We extend the Schwarzschild metric into the complex domain, employing contour integration techniques to remove ...

Embodied science and mixed reality: How gesture and motion capture affect physics education

Abstract A mixed design was created using text and game-like multimedia to instruct in the content of physics. The study assessed which variables predicted learning gains after a 1-h lesson on the electric field. The three manipulated varia...

Receptor allostery promotes context-specific Sonic Hedgehog signaling during embryonic development

Abstract Sonic Hedgehog (SHH) signaling functions in temporal- and context-dependent manners to pattern diverse tissues during embryogenesis. The signal transducer Smoothened (SMO) is induced by sterols, oxysterols, and arachidonic acid (AA...

Molecular MRI Reveals Macrophage-Enriched Peritumoral Immune Remodeling After Incomplete Ablation in Liver Cancer.

Evidence of aberrant anti-epstein-barr virus antibody response, though no viral reactivation, in people with post-stroke fatigue

Abstract Background Fatigue is a common complication of stroke that has a significant impact on quality of life. The biological mechanisms that underly post-stroke fatigue are currently unclear, however, reactivation of latent viruses and t...

Ethnomedicinal uses, phytochemistry and pharmacological aspects of the genus Premna: a review

Context: The genus Premna (Lamiaceae), distributed throughout tropical and subtropical Asia, Africa, Australia and the Pacific Islands, is used in folk medicine primarily to treat inflammation, immune-related diseases, stomach disorders, wo...

Study of the state of readiness of pharmaceutical institutions of Ukraine for implementation of integrated quality systems

One of the most promising ways to increase the efficiency of pharmaceutical enterprises in the field of quality assurance of medicines is the introduction of integrated quality systems (IQS). The aim of the work is to study of the state ...

Ospemifene for vulvar and vaginal atrophy: an overview

The menopause-related decline in estrogen levels leads to an array of genital, sexual, and urinary symptoms collectively known as genitourinary syndrome of menopause. The constellation of symptoms associated with vulvar and vaginal atrophy ...

Decision-Making Within Forensic Psychiatric Investigations: The Use of Various Information Sources by Different Expert Groups to Reach Conclusions on Legal Insanity

BackgroundWhich type of information experts use to make decisions regarding legal insanity within forensic psychiatric investigations (FPI) is relatively unknown, both in general and when considering variations due to case context. It is im...

Incidence of suicidality in people with depression over a 10-year period treated by a large UK mental health service provider

We describe the incidence of suicidality (2007–2017) in people with depression treated by secondary mental healthcare services at South London and Maudsley NHS Trust (n = 26 412). We estimated yearly incidence of ‘suicidal ideation’ and ‘hi...

UTRme: A Scoring-Based Tool to Annotate Untranslated Regions in Trypanosomatid Genomes

Most signals involved in post-transcriptional regulatory networks are located in the untranslated regions (UTRs) of the mRNAs. Therefore, to deepen our understanding of gene expression regulation, delimitation of these regions with high acc...

Loss of PRSS56 function leads to ocular angle defects and increased susceptibility to high intraocular pressure

Glaucoma is a leading cause of blindness, affecting up to 70 million people worldwide. High intraocular pressure (IOP) is a major risk factor for glaucoma. It is well established that inefficient aqueous humor (AqH) outflow resulting from s...