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Functional limitations and coping mechanisms of women aged 60 years and older with self-reported hand osteoarthritis

J. McIntyre, R.W.E. Joubert, S.S. Ramklass • South African Family Practice (2014)

Background: Hand osteoarthritis (HOA) is common in older women who seem to cope with the associated limitations in hand function. The importance of identifying coping mechanisms within a local context might have implications for interventio...

DOAJ Open Access (DOAJ) DOI: 10.1080/20786190.2014.975487

Tracking the healthcare management landscape: implications for integrated healthcare management and practice

A. Dwivedi, R.K. Bali, Raouf N.G. Naguib, Vikraman Baskaran et al. • Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) (2004)

The objective of this paper is to examine the feasibility of incorporating the Knowledge Management (KM) paradigm in healthcare. We discuss whether it would be beneficial for healthcare organisations to adopt the KM paradigm so as to facili...

OPENALEX DOI: https://doi.org/10.1109/iembs.2003.1279480

Big data in healthcare: management, analysis and future prospects

Sabyasachi Dash, Sushil Kumar Shakyawar, Mohit Sharma, Sandeep Kaushik • Journal Of Big Data (2019)

‘Big data’ is massive amounts of information that can work wonders. It has become a topic of special interest for the past two decades because of a great potential that is hidden in it. Various public and private sector industries generate,...

OPENALEX cc-by DOI: https://doi.org/10.1186/s40537-019-0217-0

Evaluation of Knowledge and Self-Reported Performance of Primary School Healthcare Providers in the City of Abarkuh City Regarding the Emergency Management of Traumatic Dental Injuries

Zahra Nafisi, Adele Pouyafard, Amene Hosseini Yekani, Hamed Gheibollahi et al. • Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd (2025)

Introduction: Dental injuries are very common and negatively affect an individual's life. The effective management of emergencies in such situations depends on the knowledge of non-experts, such as healthcare providers, who are on-site duri...

DOAJ Open Access (DOAJ)

Mortality trends among hospitalised COVID-19 patients in Sweden: A nationwide observational cohort study

Kristoffer Strålin, Erik Wahlström, Sten Walther, Anna M Bennet-Bark et al. • The Lancet Regional Health. Europe (2021)

Background: It is important to know if mortality among hospitalised COVID-19 patients has changed as the pandemic has progressed. The aim of this study was to describe the dynamics over time of mortality among patients hospitalised for COVI...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.lanepe.2021.100054

Adherence and health care costs

Iuga AO, McGuire MJ • Risk Management and Healthcare Policy (2014)

Aurel O Iuga,1,2 Maura J McGuire3,4 1Johns Hopkins Bloomberg School of Public Health, 2Johns Hopkins University, 3Johns Hopkins Community Physicians, 4Johns Hopkins University School of Medicine, Baltimore, MD, USA Abstract: Medication non...

DOAJ Open Access (DOAJ)

Why do healthcare professionals fail to escalate as per the early warning system (EWS) protocol? A qualitative evidence synthesis of the barriers and facilitators of escalation

S. M. O’Neill, B. Clyne, M. Bell, A. Casey et al. • BMC Emergency Medicine (2021)

Abstract Background Early warning systems (EWSs) are used to assist clinical judgment in the detection of acute deterioration to avoid or reduce adverse events including unanticipated cardiopulmonary arrest, admission to the intensive care ...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12873-021-00403-9

The Effect of APOE ɛ4 on the Functional Connectivity in Frontoparietal Network in Hypertensive Patients

Dandan Wang, Chang Xu, Wenxiao Wang, Hui Lu et al. • Brain Sciences (2022)

Allele 4 of the apolipoprotein E gene (APOE ε4) and hypertension are considered risk factors for Alzheimer’s Disease (AD). The detection of differences in cognitive function and brain networks between hypertensive patients who are APOE ε4 c...

DOAJ Open Access (DOAJ) DOI: 10.3390/brainsci12050515

Activation of neuronal genes via LINE-1 elements upon global DNA demethylation in human neural progenitors

Marie E Jönsson, Per Ludvik Brattås, Charlotte Gustafsson, Rebecca Petri et al. • Nature Communications (2019)

DNA methylation plays an important role in silencing transposable elements. Here the authors find that loss of DNMT1 and DNA methylation leads to transcriptional activation and chromatin remodelling of evolutionarily young—hominoid-specific...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41467-019-11150-8

Prevalence of Constipation in Elderly and Its Association With Dementia and Mild Cognitive Impairment: A Cross-Sectional Study

Fei Wang, Fei Wang, Min Fei, Min Fei et al. • Frontiers in Neuroscience (2022)

BackgroundConstipation and dementia have similar epidemiological characteristics. Changes in intestinal flora and characteristics of the brain-gut axis play roles in the pathogeneses of the two diseases, suggesting that there may be a close...

DOAJ Open Access (DOAJ) DOI: 10.3389/fnins.2021.821654

Alterations in white matter fiber density associated with structural MRI and metabolic PET lesions following multimodal therapy in glioma patients

Michel Friedrich, Ezequiel Farrher, Svenja Caspers, Svenja Caspers et al. • Frontiers in Oncology (2022)

BackgroundIn glioma patients, multimodality therapy and recurrent tumor can lead to structural brain tissue damage characterized by pathologic findings in MR and PET imaging. However, little is known about the impact of different types of d...

DOAJ Open Access (DOAJ) DOI: 10.3389/fonc.2022.998069

Hamartin: An Endogenous Neuroprotective Molecule Induced by Hypoxic Preconditioning

Sijie Li, Sijie Li, Changhong Ren, Changhong Ren et al. • Frontiers in Genetics (2020)

Hypoxic/ischemic preconditioning (HPC/IPC) is an innate neuroprotective mechanism in which a number of endogenous molecules are known to be involved. Tuberous sclerosis complex 1 (TSC1), also known as hamartin, is thought to be one such mol...

DOAJ Open Access (DOAJ) DOI: 10.3389/fgene.2020.582368

Non-genetically modified models exhibit TARDBP mRNA increase due to perturbed TDP-43 autoregulation

Akihiro Sugai, Taisuke Kato, Akihide Koyama, Yuka Koike et al. • Neurobiology of Disease (2019)

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by accumulation of fragmented insoluble TDP-43 and loss of TDP-43 from the nucleus. Increased expression of exogenous TARDBP (encoding TDP-43) induces TDP-43 p...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.nbd.2019.104534

Neuroscience in Medicine

P. Michael Conn • Humana Press eBooks (2003)

Cytology and Organization of Cell Types: Light and Electron Microscopy Rochelle S. Cohen and Donald W. Pfaff Anatomy of the Spinal Cord and Brain Bruce E. Maley Ion Channels and Electrical Signaling Stanko S. Stojilkovic A. Clinical Correla...

OPENALEX DOI: https://doi.org/10.1007/978-1-59259-371-2

Circular RNA expression profiles and functional predication after restraint stress in the amygdala of rats

Chuan Wang, Qian Wang, Guangming Xu, Guangming Xu et al. • Frontiers in Molecular Neuroscience (2024)

Prolonged or repeated exposure to stress elevates the risk of various psychological diseases, many of which are characterized by central nervous system dysfunction. Recent studies have demonstrated that circular RNAs (circRNAs) are highly a...

DOAJ Open Access (DOAJ) DOI: 10.3389/fnmol.2024.1381098

Prefrontal cortical deficits are a putative susceptibility factor for PTSD

Rebecca Nalloor, Rebecca Nalloor, Khadijah Shanazz, Khadijah Shanazz et al. • Frontiers in Behavioral Neuroscience (2026)

IntroductionOnly a subset of people who experience a traumatic event develop Post-Traumatic Stress Disorder (PTSD) suggesting that there are susceptibility factors influencing PTSD pathophysiology. While post trauma sequelae factors are ext...

DOAJ Open Access (DOAJ) DOI: 10.3389/fnbeh.2026.1750991

Toward an integrated approach for mental health and psychosocial support and peacebuilding in North-East Nigeria: programme description and preliminary outcomes from ‘Counselling on Wheels’

Sharli Paphitis, Fatima Akilu, Natasha Chilambo, Abiye Iruayenama et al. • BJPsych Open (2023)

Background Despite theoretical support for including mental health and psychosocial support (MHPSS) with peacebuilding, few programmes in conflict-affected regions fully integrate these approaches. Aims To describe and assess preliminary o...

DOAJ Open Access (DOAJ) DOI: 10.1192/bjo.2023.575

Fipronil disturbs the antigen-specific immune responses and GABAergic gene expression in the ovalbumin-immunized BALB/c mice

Jui-Fang Kuo, Yin-Hua Cheng, Chun-Wei Tung, Chia-Chi Wang • BMC Veterinary Research (2024)

Abstract Background Fipronil (FPN) is a broad-spectrum pesticide and commonly known as low toxicity to vertebrates. However, increasing evidence suggests that exposure to FPN might induce unexpected adverse effects in the liver, reproductiv...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12917-024-03878-3