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Role of N343 glycosylation on the SARS-CoV-2 S RBD structure and co-receptor binding across variants of concern

Callum M Ives, Linh Nguyen, Carl A Fogarty, Aoife M Harbison et al. • eLife (2024)

Glycosylation of the SARS-CoV-2 spike (S) protein represents a key target for viral evolution because it affects both viral evasion and fitness. Successful variations in the glycan shield are difficult to achieve though, as protein glycosyl...

DOAJ Open Access (DOAJ) DOI: 10.7554/eLife.95708

Arts in NEOM project Civilized progress in the northern region in Saudi Arabia kingdom

Wadiah Boker • Journal of Architecture, Art & Humanistic Science (2021)

Here in Saudi Arabia kingdom we are facing a scientific revolution that accompany the economic project NEOM that has been launched by the country in the northern lands of the kingdom where a certain set of goals have been assigned for it, t...

DOAJ Open Access (DOAJ) DOI: 10.21608/mjaf.2020.27853.1578

Future Protein Supply and Demand: Strategies and Factors Influencing a Sustainable Equilibrium

Maeve Henchion, Maria Hayes, Anne Maria Mullen, Mark Fenelon et al. • Foods (2017)

A growing global population, combined with factors such as changing socio-demographics, will place increased pressure on the world’s resources to provide not only more but also different types of food. Increased demand for animal-based prot...

DOAJ Open Access (DOAJ) DOI: 10.3390/foods6070053

A Novel Peptide Antibiotic Produced by Streptomyces roseoflavus Strain INA-Ac-5812 With Directed Activity Against Gram-Positive Bacteria

Alexey S. Vasilchenko, William T. Julian, Olda A. Lapchinskaya, Genrikh S. Katrukha et al. • Frontiers in Microbiology (2020)

In this work, we report the isolation and detailed functional characterization for the new non-ribosomally synthesized antibiotic 5812-A/C, which was derived from metabolites of Streptomyces roseoflavus INA-Ac-5812. According to its chemica...

DOAJ Open Access (DOAJ) DOI: 10.3389/fmicb.2020.556063

Functionalising Collagen-Based Scaffolds With Platelet-Rich Plasma for Enhanced Skin Wound Healing Potential

Ronaldo J. F. C. do Amaral, Ronaldo J. F. C. do Amaral, Ronaldo J. F. C. do Amaral, Noora M. A. Zayed et al. • Frontiers in Bioengineering and Biotechnology (2019)

Porous collagen-glycosaminoglycan (collagen-GAG) scaffolds have shown promising clinical results for wound healing; however, these scaffolds do not replace the dermal and epidermal layer simultaneously and rely on local endogenous signaling...

DOAJ Open Access (DOAJ) DOI: 10.3389/fbioe.2019.00371

Ion Mobility Mass Spectrometry Reveals Rare Sialylated Glycosphingolipid Structures in Human Cerebrospinal Fluid

Mirela Sarbu, Dragana Fabris, Željka Vukelić, David E. Clemmer et al. • Molecules (2022)

Gangliosides (GGs) represent an important class of biomolecules associated with the central nervous system (CNS). In view of their special role at a CNS level, GGs are valuable diagnostic markers and prospective therapeutic agents. By ion m...

DOAJ Open Access (DOAJ) DOI: 10.3390/molecules27030743

The detection of trans gene fragments of hEPO in gene doping model mice by Taqman qPCR assay

Kai Aoki, Takehito Sugasawa, Kouki Yanazawa, Koichi Watanabe et al. • PeerJ (2020)

Background With the rapid progress of genetic engineering and gene therapy methods, the World Anti-Doping Agency has raised concerns regarding gene doping, which is prohibited in sports. However, there is no standard method available for de...

DOAJ Open Access (DOAJ) DOI: 10.7717/peerj.8595

Analysis of the status and framework design of intelligentcoal mine auxiliary transportation system

CHANG Kai, LIU Zhigeng, YUAN Xiaoming, LI Yuan • Gong-kuang zidonghua (2022)

This paper introduces the development and application status of intelligent auxiliary transportation technology in open-pit coal mine and underground coal mines at home and abroad. The intelligent auxiliary transportation system of open-pit...

DOAJ Open Access (DOAJ) DOI: 10.13272/j.issn.1671-251x.2022010052

Bone fracture detection through the two-stage system of Crack-Sensitive Convolutional Neural Network

Yangling Ma, Yixin Luo • Informatics in Medicine Unlocked (2021)

Automated fracture detection is an essential part in a computer-aided tele-medicine system. Fractures often occur in human's arbitrary bone due to accidental injuries such as slipping. In fact, many hospitals lack experienced surgeons to di...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.imu.2020.100452

Evaluation of Indicators for the Realization of the Development of Public-Oriented Urban Transportation (Study Case: District 11 of Tehran)

Sayyed Jalal Aldin Hosseini, Azita Rajabi, Afshin Safahan, Aliasghar Rezvani • برنامه‌ریزی توسعه شهری و منطقه‌ای (2024)

Transit-Oriented Development (TOD) represents a significant facet of sustainable urban planning aimed at addressing urban traffic challenges through the strategic expansion of public transportation systems. District 11 within the municipali...

DOAJ Open Access (DOAJ) DOI: 10.22054/urdp.2023.55092.1248

Mpox as Two Global Health Emergencies: Altered Transmission, Genomics, Clinical Manifestation and Public Health Impact

Sanchita Chakraborty, S.R. Rao, Abhijit Poddar • Infectious Microbes & Diseases (2025)

Mpox virus (MPXV) is the only pathogen that triggered two Public Health Emergency of International Concern (PHEIC) declarations, first in July 2022 and then again in August 2024. The 2022 outbreak was attributed primarily to clade IIb MPXV,...

DOAJ Open Access (DOAJ) DOI: 10.1097/IM9.0000000000000196

State of the Art and Environmental Aspects of Plant Microbial Fuel Cells’ Application

Roman Lepikash, Daria Lavrova, Devard Stom, Valery Meshalkin et al. • Energies (2024)

Environmental pollution is becoming ubiquitous; it has a negative impact on ecosystem diversity and worsens the quality of human life. This review discusses the possibility of applying the plant microbial fuel cells (PMFCs) technology for c...

DOAJ Open Access (DOAJ) DOI: 10.3390/en17030752

Antioxidant, Wound Healing Potential and In Silico Assessment of Naringin, Eicosane and Octacosane

Abbirami Balachandran, Sy Bing Choi, Morak-Młodawska Beata, Jeleń Małgorzata et al. • Molecules (2023)

1. Diabetic chronic wounds, mainly foot ulcers, constitute one of the most common complications of poorly managed diabetes mellitus. The most typical reasons are insufficient glycemic management, latent neuropathy, peripheral vascular disea...

DOAJ Open Access (DOAJ) DOI: 10.3390/molecules28031043

Antibiogram Profile and Resistance Patterns of Microflora from Vaginal Discharge in Reproductive-age Women at a Nigerian Teaching Hospital

Chizoba M. Enemchukwu, Christiana Nwabueze, Oluchi J. Osuala, Chinedu J. Ikem et al. • RADS Journal of Biological Research & Applied Science (2024)

Background: The adult human vagina hosts a complex biota containing diverse communities of microorganisms. The occurrence of multi-drug-resistant strains of these microorganisms has persistently increased due to poor hygiene and misuse or a...

DOAJ Open Access (DOAJ)

Unveiling the levels and significance of different serpin family proteins in aqueous humor dynamics

Eliza Williams, Jeremy Altman, Saleh Ahmed, Garrett Jones et al. • BMC Ophthalmology (2025)

Abstract Background Alterations in the constituents of the aqueous humor (AH) are associated with various ocular pathologies, including primary open-angle glaucoma (POAG). AH contains a variety of immunomodulatory molecules, including serin...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12886-025-04119-3

Structure and transport mechanism of P5B-ATPases

Ping Li, Kaituo Wang, Nina Salustros, Christina Grønberg et al. • Nature Communications (2021)

In human cells, P5B‐ATPases execute export of spermine from lysosomes to the cytosol, but the mechanisms of spermine recognition, uptake and transport remain elusive. Here the authors present cryo‐EM structures of a yeast homolog of human A...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41467-021-24148-y

Flavanol-Rich Cocoa Supplementation Inhibits Mitochondrial Biogenesis Triggered by Exercise

Jose Angel García-Merino, Beatriz de Lucas, Karen Herrera-Rocha, Diego Moreno-Pérez et al. • Antioxidants (2022)

The potential role of cocoa supplementation in an exercise context remains unclear. We describe the effects of flavanol-rich cocoa supplementation during training on exercise performance and mitochondrial biogenesis. Forty-two male enduranc...

DOAJ Open Access (DOAJ) DOI: 10.3390/antiox11081522

Exploring the cultural influence of Turkish TV dramas: a mixed‑methods study among Tunisian viewers

Ferhat Kaçar, İrfan Hıdıroğlu • Cogent Arts & Humanities (2026)

The Turkish television series industry has experienced significant growth over the past twenty years and has gained widespread popularity both domestically and internationally. This expansion has generated economic value while reinforcing T...

DOAJ Open Access (DOAJ) DOI: 10.1080/23311983.2026.2680621