Reset
Showing 20 of 2,687 academic articles

Association of SLC6A3 variants with treatment-resistant schizophrenia: a genetic association study of dopamine-related genes in schizophrenia

Masanobu Kogure, Nobuhisa Kanahara, Atsuhiro Miyazawa, Atsuhiro Miyazawa et al. • Frontiers in Psychiatry (2024)

BackgroundMost genetic analyses that have attempted to identify a locus or loci that can distinguish patients with treatment-resistant schizophrenia (TRS) from those who respond to treatment (non-TRS) have failed. However, evidence from mul...

DOAJ Open Access (DOAJ) DOI: 10.3389/fpsyt.2023.1334335

Emodin inhibits Newcastle disease virus replication via regulating the phosphorylation levels of eEF2K/eEF2 and targeting viral N protein to reduce viral protein production

Wenjie Wu, Rongjing Xia, Si Ma, Zenglei Hu et al. • Poultry Science (2026)

Newcastle disease (ND) caused by Newcastle disease virus (NDV) infection is a highly contagious avian disease that causes substantial threat to the global poultry industry. Emodin (EMO), a member of the free anthraquinone compounds derived ...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.psj.2026.107180 PMC: PMC13265661

Divergent biological consequences of APOE isoforms across industrialized and non-industrial environments.

Marina M Watowich, Rachel M Petersen, Layla Brassington, Audrey M Arner et al. • PLoS Genetics (2026)

The apolipoprotein ε4 (APOE ε4) isoform directly alters cholesterol and immune biology and is associated with an increased risk of neurodegenerative and cardiometabolic disease in industrialized settings; nevertheless, APOE ε4-which is ance...

DOAJ Open Access (DOAJ) DOI: 10.1371/journal.pgen.1012285

Near infrared spectroscopy predicts crude protein concentration in hemp grain

Ryan V. Crawford, Jamie L. Crawford, Julie L. Hansen, Lawrence B. Smart et al. • Agrosystems, Geosciences & Environment (2026)

Abstract This study evaluated near‐infrared spectroscopy (NIRS) for nondestructive crude protein (CP) prediction in hemp (Cannabis sativa L.) grain and validated the biological basis of spectral predictions. Note that 149 whole grain sample...

DOAJ Open Access (DOAJ) DOI: 10.1002/agg2.70328

SUMO E3 ligase Mms21 prevents spontaneous DNA damage induced genome rearrangements.

Jason Liang, Bin-Zhong Li, Alexander P Tan, Richard D Kolodner et al. • PLoS Genetics (2018)

Mms21, a subunit of the Smc5/6 complex, possesses an E3 ligase activity for the Small Ubiquitin-like MOdifier (SUMO). Here we show that the mms21-CH mutation, which inactivates Mms21 ligase activity, causes increased accumulation of gross c...

DOAJ Open Access (DOAJ) DOI: 10.1371/journal.pgen.1007250

BRI1 EMS SUPPRESSOR1 genes regulate abiotic stress and anther development in wheat (Triticum aestivum L.)

Dezhou Wang, Dezhou Wang, Jinghong Zuo, Jinghong Zuo et al. • Frontiers in Plant Science (2023)

BRI1 EMS SUPPRESSOR1 (BES1) family members are crucial downstream regulators that positively mediate brassinosteroid signaling, playing vital roles in the regulation of plant stress responses and anther development in Arabidopsis. Important...

DOAJ Open Access (DOAJ) DOI: 10.3389/fpls.2023.1219856

The estimation of canopy attributes from digital cover photography by two different image analysis methods

Chianucci F, Chiavetta U, Cutini A • iForest - Biogeosciences and Forestry (2014)

Proximal sensing methods using digital photography have gained wide acceptance for describing and quantifying canopy properties. Digital hemispherical photography (DHP) is the most widely used photographic technique for canopy description. ...

DOAJ Open Access (DOAJ) DOI: 10.3832/ifor0939-007

Compost Increases Soil Fertility and Promotes the Growth of Five Tropical Species Used in Urban Forestry

Silvia Melissa Manrique-Veja, Oscar Alvarado-Sanabria • Floresta e Ambiente (2023)

Abstract This study aims at assessing the impact of compost application on the physical (porosity, volumetric-moisture and bulk density) and the chemical traits of soil (pH, organic carbon, electrical conductivity, cation exchange capacity ...

DOAJ Open Access (DOAJ) DOI: 10.1590/2179-8087-floram-2023-0018

Analysis of Cathinone Alkaloids in Khat by HPLC-Q-TOF In-source Fragmentation Multistage Mass Spectrometry

SHI Hong-fei1, XU Bo-peng1, QUAN Yang-ke2, XU Cheng-xin1, ZHOU Xiu-qi1 • Zhipu Xuebao (2024)

Khat is a kind of common drug plant. Many experiments have shown that the content of cathinone norpseudoephedrine and norephedrine in some varieties of Khat are similar. However, some studies showed that there are differences in the intensi...

DOAJ Open Access (DOAJ) DOI: 10.7538/zpxb.2023.0065

miR-3113-5p, miR-223-3p, miR-133a-3p, and miR-499a-5p are sensitive biomarkers to diagnose sudden cardiac death

Fengping Yan, Yuanyuan Chen, Xing Ye, Fu Zhang et al. • Diagnostic Pathology (2021)

Abstract Background Sudden cardiac death (SCD) remains a great health threat and diagnostic challenge, especially those cases without positive autopsy findings. Molecular biomarkers have been urgently needed for the diagnosis of SCD display...

DOAJ Open Access (DOAJ) DOI: 10.1186/s13000-021-01127-x

Does wet-cupping therapy improve repeated sprint ability, perceived wellness, and rating of perceived exertion in young active males?

Ismail Dergaa, Amine Ghram, Mohamed Romdhani, Amine Souissi et al. • Sports Medicine and Health Science (2024)

Wet-cupping therapy (WCT) is one of the oldest known medical techniques, used as a traditional and complementary therapy with a wide application all around the world for general health. Research on the effects of WCT on sports performance a...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.smhs.2023.09.007

Human rights and humanitarian forensic action: the experience in Uruguay

Hugo Rodríguez Almada, Frances Borches Duhalde, Victoria Iglesias Salaverría • Forensic Sciences Research (2022)

Humanitarian Forensic Action (HFA) is considered a new field of Forensic Medicine and Forensic Sciences where the forensic science is applied to different humanitarian activities. In Uruguay, the HFA has been developed based on internationa...

DOAJ Open Access (DOAJ) DOI: 10.1080/20961790.2022.2052591

Cadmium sulfide-induced toxicity in the cortex and cerebellum: In vitro and in vivo studies

Atefeh Varmazyari, Ali Taghizadehghalehjoughi, Cigdem Sevim, Ozlem Baris et al. • Toxicology Reports (2020)

Living organisms have an innate ability to regulate the synthesis of inorganic materials, such as bones and teeth in humans. Cadmium sulfide (CdS) can be utilized as a quantum dot that functions as a unique light-emitting semiconductor nano...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.toxrep.2020.04.011

UPLC-MS/MS Metabolomics Reveals Babao Dan’s Mechanisms in MASH Treatment with Integrating Network Pharmacology and Molecular Docking

Shijiao Zhang, Yanding Su, Ao Han, He Qi et al. • Pharmaceuticals (2025)

Background: Metabolic dysfunction-associated steatohepatitis (MASH) is a progressive disease that easily develops into cirrhosis and hepatocellular carcinoma, but its pathogenesis is not clear, and most therapeutic drugs have obvious limita...

DOAJ Open Access (DOAJ) DOI: 10.3390/ph18081111

Impact of <i>Chlorella vulgaris</i> Bioremediation and Selenium on Genotoxicity, Nephrotoxicity and Oxidative/Antioxidant Imbalance Induced by Polystyrene Nanoplastics in African Catfish (<i>Clarias gariepinus</i>)

Shimaa A. Abdelbaky, Zakaria M. Zaky, Doha Yahia, Mohamed H. Kotob et al. • Fishes (2024)

Contamination of the environment with nano- and microplastic particles exerts a threatening impact on the aquatic ecosystems and sustainable catfish aquaculture. The presence of nanoplastics has been found to have a detrimental impact on bo...

DOAJ Open Access (DOAJ) DOI: 10.3390/fishes9020076

Autism Spectrum Disorder and collective catering service: results of the pilot study FOOD-AUT

Maria Vittoria Conti, Sara Santero, Chiara Breda, Sara Basilico et al. • Frontiers in Nutrition (2024)

ObjectiveIndividuals with Autism Spectrum Disorder (ASD) often exhibit a low dietary diversity due to food selectivity that leads them to a marked preference for high-energy-density food, exposing them to risk of malnutrition. Despite these...

DOAJ Open Access (DOAJ) DOI: 10.3389/fnut.2023.1298469

Alterations in the gut microbiota and its metabolites contribute to metabolic maladaptation in dairy cows during the development of hyperketonemia

Zhengzhong Luo, Zhenlong Du, Yixin Huang, Tao Zhou et al. • mSystems (2024)

ABSTRACTMetabolic maladaptation in dairy cows after calving can lead to long-term elevation of ketones, such as β-hydroxybutyrate (BHB), representing the condition known as hyperketonemia, which greatly influences the health and production ...

DOAJ Open Access (DOAJ) DOI: 10.1128/msystems.00023-24