Academic Articles & Research Papers

Developing an Ethical Regulatory Framework for Artificial Intelligence: Integrating Systematic Review, Thematic Analysis, and Multidisciplinary Theories

Artificial intelligence (AI) ethics has emerged as a global discourse within both academic and policy spheres. However, translating these principles into concrete, real-world applications for AI development remains a pressing need and a sig...

Prediction of Seven Artificial Intelligence-Based Intraocular Lens Power Calculation Formulas in Medium-Long Caucasian Eyes

Purpose: To compare the accuracy of seven artificial intelligence (AI)-based intraocular lens (IOL) power calculation formulas in medium-long Caucasian eyes regarding the root-mean-square absolute error (RMSAE), the median absolute error (M...

Oxytocin Signalling in Lower Urinary Tract Symptoms Associated with Benign Prostatic Hyperplasia and Overactive Bladder Syndrome: A Narrative Review

Lower urinary tract symptoms (LUTSs) associated with benign prostatic disease and overactive bladder syndrome (OAB) substantially impair quality of life. This narrative review evaluates oxytocin receptor (OXTR) localisation, signalling, and...

Generality in artificial intelligence

My 1971 Turing Award Lecture was entitled "Generality in Artificial Intelligence." The topic turned out to have been overambitious in that I discovered I was unable to put my thoughts on the subject in a satisfactory written form at that ti...

Precision Periodontics: Reimagining Periodontal Care through Precision Diagnostics and Targeted Therapies

Periodontitis is a chronic inflammatory disease that affects the tissues supporting teeth and represents a significant global health issue. Traditional diagnostic and treatment methods often use a broad approach and fall short due to the co...

Assessing carbon and economic loss from oak decline in Iran’s Zagros forests using Sentinel-2 and machine learning

Over recent decades, the decline of oak trees, which has emerged as the most significant challenge to the Zagros forests (ZFs), poses serious threats to carbon storage (CS) and economic valuation, jeopardizing the ecological and economic su...

Binaural Beat Stimulation Enhances Cognitive Function in Alzheimer’s Disease via Temporal Lobe Activation: An sLORETA Study

Background: The global prevalence of Alzheimer’s disease (AD) has reached 55.2 million. AD is characterized by progressive deterioration in cognition and working memory (WM), which are essential for attention, reasoning, and learning. These...

Mapping artificial intelligence research in higher education toward sustainable development

Abstract The rapid development of Artificial Intelligence (AI) has had a profound impact on higher education (HE), fundamentally changing teaching, learning, research and academic management. Although there have been many studies on the app...

Golgi dysfunction in Alzheimer disease: from human multiomic signatures to therapeutic targets.

Radiomics and radiogenomics: extracting more information from medical images for the diagnosis and prognostic prediction of ovarian cancer

Abstract Ovarian cancer (OC) remains one of the most lethal gynecological malignancies globally. Despite the implementation of various medical imaging approaches for OC screening, achieving accurate differential diagnosis of ovarian tumors ...

Artificial intelligence in glaucoma

PURPOSE OF REVIEW: The use of computers has become increasingly relevant to medical decision-making, and artificial intelligence methods have recently demonstrated significant advances in medicine. We therefore provide an overview of curren...

A bibliometric analysis of industry 4.0 digital manufacturing and smart technologies for sustainable development

Abstract This study provides a broad bibliometric analysis of Industry 4.0 as well as technology-based production systems within the appropriate scientific literature to target the description of the dynamic structure, intellectual foundati...

Predictive digital twin for optimizing patient-specific radiotherapy regimens under uncertainty in high-grade gliomas

We develop a methodology to create data-driven predictive digital twins for optimal risk-aware clinical decision-making. We illustrate the methodology as an enabler for an anticipatory personalized treatment that accounts for uncertainties ...

Prediction of homologous recombination deficiency from routine histology with attention-based multiple instance learning in nine different tumor types

Abstract Background Homologous recombination deficiency (HRD) is recognized as a pan-cancer predictive biomarker that potentially indicates who could benefit from treatment with PARP inhibitors (PARPi). Despite its clinical significance, HR...

A satellite-derived, ground-measurement-independent monthly PM2.5 mass concentration dataset over China during 2000 - 2015

Following the accelerated development of urbanization and industrialization, atmospheric particulate matter has become a significant threat to public health globally. Environmental health studies usually use the mass concentration of fine p...

Cardiomyocyte-enriched OTUD5 alleviates pathological myocardial hypertrophy by deubiquitinating STAT3 and modulating the STAT3-PGC-1α axis.

BioHarness: substrate-aware evidence assembly for biomedical question answering across literature, knowledge bases, and biological atlases.

Designing novel linagliptin analogs through combined generative artificial intelligence, molecular docking, molecular dynamics simulation, and binding energy estimation for targeting fibroblast activation protein

Fibroblast activation protein (FAP) is a highly specific biomarker overexpressed in cancer-associated fibroblasts, making it a promising diagnostic target. Developing novel high-affinity molecular probes for FAP-targeted diagnostics remains...

Preoperative and Prognostic Prediction of Microvascular Invasion in Hepatocellular Carcinoma: A Review Based on Artificial Intelligence

Microvascular invasion of hepatocellular carcinoma is an important factor affecting tumor recurrence after liver resection and liver transplantation. There are many ways to classify microvascular invasion, however, an international consensu...

Association of epicardial adipose tissue with circulating biomarkers in paroxysmal atrial fibrillation: insights from the RACE V study.