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Antibody response after pneumococcal vaccination in a large cohort of Italian children and adolescents with Down syndrome

Antonio Musolino, Marco Roversi, Mariateresa Romaniello, Vittorio Scoppola et al. • Vaccine: X (2025)

Introduction: Pneumococcal vaccination has significantly decreased the burden of invasive pneumococcal disease in the general population, however studies on effectiveness in Down syndrome (DS) are heterogeneous. In this cross-sectional stud...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.jvacx.2025.100744

Prevalence of Obesity and Malnutrition among School-Aged Children of the District Peshawar

Usman Shah1, Usman Saeed2, Maryam Bibi3,, , Shakir Ullah3 et al. • Egyptian Journal of Nutrition (2024)

ABSTRACTMalnutrition and Obesity are worldwide health phenomena so the aims of the study were to assist the prevalence of obesity and malnutrition among school-aged children of the district Peshawar. Institutional based cross-sectional stud...

DOAJ Open Access (DOAJ) DOI: 10.21608/enj.2024.391626

Medical biotechnology

Findlay, Joshua • University of Salford Institutional Repository (University of Salford) (2016)

Resistance to entering the UK government's modern slavery victim identification mechanism is widespread and part of normal practices of state evasion that shape the lives of large numbers of insufficiently documented people.This article pro...

OPENALEX cc-by

Poly (ADP-ribose) Polymerase Promoter Hypermethylation Predispose Females to Breast Cancer

Hussein Sabit, Shaimaa Nazir, Shimaa Abdel-Ghany, Osama A. Said et al. • Asian Pacific Journal of Cancer Biology (2019)

Being the most common cause of female deaths worldwide, breast cancer (BC) is intensively studied over the last two decades. In the present investigation, we evaluated the promoter methylation of three cancer-related genes; PARP-1, p21, and...

DOAJ Open Access (DOAJ) DOI: 10.31557/apjcb.2019.4.1.1-5

Medical Biotechnology in Society

Helen W. Kreuzer, Adrianne Massey • ASM Press eBooks (2014)

This chapter provides relevant scientific and historical information relating to genetic testing and human embryonic stem (hES) cell therapies and describes some of the societal issues surrounding them. The risks of invasive diagnostic test...

OPENALEX DOI: https://doi.org/10.1128/9781555816094.ch20

Impact of Prolonged COVID-19 Lockdown on Body Mass Index, Eating Habits, and Physical Activity of University Students in Bangladesh: A Web-Based Cross-Sectional Study

Md. Jamal Hossain, Foyez Ahmmed, Md. Robin Khan, Parisa Tamannur Rashid et al. • Frontiers in Nutrition (2022)

ObjectivesThis current study aims to assess the prevalence and factors associated with body mass index (BMI), dietary patterns, and the extent of physical activities among university students following the prolonged coronavirus disease 2019...

DOAJ Open Access (DOAJ) DOI: 10.3389/fnut.2022.873105

A Novel Prognostic Scoring Model for Myelodysplastic Syndrome Patients With SF3B1 Mutation

Liya Ma, Bin Liang, Huixian Hu, Wenli Yang et al. • Frontiers in Oncology (2022)

The outcomes of myelodysplastic syndrome (MDS) patients with SF3B1 mutation, despite identified as a favorable prognostic biomarker, are variable. To comprehend the heterogeneity in clinical characteristics and outcomes, we reviewed 140 MDS...

DOAJ Open Access (DOAJ) DOI: 10.3389/fonc.2022.905490

Dynamic monitoring of circulating tumor DNA reveals outcomes and genomic alterations in patients with relapsed or refractory large B-cell lymphoma undergoing CAR T-cell therapy

Wei Liu, Yan Xu, Yi Wang, Lugui Qiu et al. • Journal for ImmunoTherapy of Cancer (2024)

Background Over 50% of patients with relapsed or refractory large B-cell lymphoma (r/r LBCL) receiving CD19-targeted chimeric antigen receptor (CAR19) T-cell therapy fail to achieve durable remission. Early identification of relapse or prog...

DOAJ Open Access (DOAJ) DOI: 10.1136/jitc-2023-008450

Single-cell RNA-seq reveals the genesis and heterogeneity of tumor microenvironment in pancreatic undifferentiated carcinoma with osteoclast-like giant-cells

Xinbo Wang, Jiaying Miao, Sizhen Wang, Rongxi Shen et al. • Molecular Cancer (2022)

Abstract Background Undifferentiated carcinoma with osteoclast-like giant cells (OGCs) of pancreas (UCOGCP) is a rare subtype of pancreatic ductal adenocarcinoma (PDAC), which had poorly described histopathological and clinical features. Me...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12943-022-01596-8

Detrimental alteration of mesenchymal stem cells by an articular inflammatory microenvironment results in deterioration of osteoarthritis

Mengqiang Fan, Peijian Tong, Li Yan, Ting Li et al. • BMC Medicine (2023)

Abstract Background Articular injection of mesenchymal stem cells (MSCs) has been applied to treat knee osteoarthritis (kOA), but its clinical outcomes are controversial. This study investigated whether an articular inflammatory microenviro...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12916-023-02923-6

Absence of Asymptomatic Malaria Infection in Endemic Area of Bashagard District, Hormozgan Province, Iran

H Turki, S Zoghi, A A Mehrizi, S Zakeri et al. • Iranian Journal of Parasitology (2012)

Background: A successful malaria elimination program calls for enough attention to parasite carri­ers, especially asymptomatic malaria, as well as the diagnosis and treatment of clinical cases. Asymptomatic malaria is an infection that pati...

DOAJ Open Access (DOAJ)

Accomplishments in genome‐scale in silico modeling for industrial and medical biotechnology

Caroline B. Milne, Pan‐Jun Kim, James A. Eddy, Nathan D. Price • Biotechnology Journal (2009)

Driven by advancements in high-throughput biological technologies and the growing number of sequenced genomes, the construction of in silico models at the genome scale has provided powerful tools to investigate a vast array of biological sy...

OPENALEX Open Access DOI: https://doi.org/10.1002/biot.200900234 PMC: 3160784

Regulatory requirements for the registration of generic medicines and format of drug dossiers: procedures in Sri Lanka in comparison with selected regulatory authorities

D. Thambavita, P. Galappatthy, R. L. Jayakody • Journal of Pharmaceutical Policy and Practice (2018)

Background The regulatory requirements for approval of generic medicines and the format of compiling drug dossiers vary among regulatory authorities. The variation is particularly wide between High-income countries (HIC) and lower and middl...

DOAJ Open Access (DOAJ) DOI: 10.1186/s40545-018-0141-2

How Does the Diversity of Divers Affect the Design of Citizen Science Projects?

María I. Hermoso, María I. Hermoso, Victoria Y. Martin, Wolfgang Stotz et al. • Frontiers in Marine Science (2019)

Divers have widely participated in citizen science (CS) projects and are one of the main groups of marine citizen scientists. However, there is little knowledge about profiles of, and incentives for potential divers to join CS projects. To ...

DOAJ Open Access (DOAJ) DOI: 10.3389/fmars.2019.00239

Library in the Сontext of Gender Studies as an Information Model for the Transformation of Gender Identities

Chernjavskaja Lina • Наукові праці Національної бібліотеки України імені В.І. Вернадського (2018)

The article deals with the role of libraries in study of gender processes occurring in the social structure of modern society. The emphasis is placed on the fact that the objective conditions of modern society influence the changes in the i...

DOAJ Open Access (DOAJ)

Developing and defining core climate and environmental epidemiology competencies for field epidemiology training programs in the Eastern Mediterranean Region: a Delphi study

Yousef Khader, Muhammad Sartaj, Mohannad Al Nsour, Ruba Kamal Alsouri et al. • Frontiers in Public Health (2026)

BackgroundClimate change, environmental degradation, and chemical hazards increasingly shape population health risks, particularly in the Eastern Mediterranean Region (EMR), where water scarcity, rapid urbanization, conflict, and fragile he...

DOAJ Open Access (DOAJ) DOI: 10.3389/fpubh.2026.1902013