Academic Articles & Research Papers

Medical informatics in postgraduate training

Fixed-parameter tractable sampling for RNA design with multiple target structures

Abstract Background The design of multi-stable RNA molecules has important applications in biology, medicine, and biotechnology. Synthetic design approaches profit strongly from effective in-silico methods, which substantially reduce the ne...

The Effectiveness of Digital Therapeutics Intervention in Oral Anticoagulation Management: A Systematic Review and Meta-analysis

Objective: To summarize the key intervention characteristics and evaluate the effectiveness and safety of digital therapeutics (DTx) in patients receiving oral anticoagulation, with effectiveness evaluated using time in therapeutic range (T...

Percutaneous CT-Guided Bone Lesion Biopsy for Confirmation of Bone Metastases in Patients with Breast Cancer

We aimed to determine diagnostic accuracy of CT-guided bone lesion biopsy for the confirmation of bone metastases in patients with breast cancer and assessment of hormone receptor status in metastatic tissue. A total of 56 female patients w...

Medical Informatics and Pediatrics

Decision support is an important area of medical informatics research. Computer-based decision-support tools facilitate diagnosis and the management of patients after a diagnosis has been established. Diagnostic decision-support tools, such...

Medical Informatics, Art or Science?

The Questions of Medical Informatics

Each science is identified with the questions it raises with respect to its object of study. This paper discussed the formulation of the basic questions of medical informatics. From a historical point of view, it first dealt with the proble...

Challenges in Medical Informatics: Perspectives of an International Medical Informatics Organization

OBJECTIVE: As an international organization with the missions to promote informatics in health care and biomedical research, advance international cooperation, stimulate research, development and education, and disseminate and exchange info...

Secondary research use of personal medical data: patient attitudes towards data donation

Abstract Background The SARS-CoV-2 pandemic has highlighted once more the great need for comprehensive access to, and uncomplicated use of, pre-existing patient data for medical research. Enabling secondary research-use of patient-data is a...

An updated database of human maximum skin fluxes and epidermal permeability coefficients for drugs, xenobiotics, and other solutes applied as aqueous solutions

The dataset represented in this article is referred to by the review article entitled “Topical drug delivery: history, percutaneous absorption, and product development” (MS Roberts et al., 2021) [1]. The dataset contains maximal flux (Jmax)...

Grey matter volume associations with personality functioning in a clinical cohort of female youths

Borderline Personality Disorder (BPD) is a severe mental illness, although its neurobiological underpinnings remain largely unknown. Structural Magnetic Resonance Imaging (sMRI) in adolescents can offer insights into potential biomarkers to...

Correction: Five-year dementia prediction and decision support system based on real-world data

Medical informatics and information

Medical informatics has now been in existence for approximately 40 years, and it has been rapidly growing in the last decade. Despite major advantages in the science and technology of health care, it seems that the medical informatics disci...

Medical Informatics and Bioinformatics

In the last 50 years, computational applications have been developed to aid clinicians and researchers alike in the broad field of Biomedicine. Adopted early in the evolution of the field, the term medical informatics has been applied to th...

Progress with Formalization in Medical Informatics?

The prevailing view of medical informatics as a primarily subservient discipline in health care is challenged. Developments in both general informatics and medical informatics are described to identify desirable properties of modeling langu...

Medical informatics--an interdisciplinary approach.

Medical informatics is the first science that has incorporated all traditional medical disciplines. That progress is possible due to fast development of new technologies, particularly in informatics, as well as due to common needs of all me...

Medical Informatics: Searching for Underlying Components

OBJECTIVE: To discuss unifying principles that can provide a theory for the diverse aspects of work in medical informatics. If medical informatics is to have academic credibility, it must articulate a clear theory that is distinct from that...

Medical Informatics: Computer Applications in Health Care

The formidable title of this well-written textbook belies its readability and usefulness. While the termsinformaticsandcomputerscan turn all but the computer literate away in disinterest or even fear, this book is useful to many, computerop...

Medical informatics in context

Abstract Medical informatics may be defined as “the application of information science and information technology to the theoretical and practical problems of biomedical research, clinical practice, and medical education.” As such, it has b...

Bioinformatics and Medical Informatics: Collaborations on the Road to Genomic Medicine?

In this report, the authors compare and contrast medical informatics (MI) and bioinformatics (BI) and provide a viewpoint on their complementarities and potential for collaboration in various subfields. The authors compare MI and BI along s...