Academic Articles & Research Papers

Network dynamics underlying OFF responses in the auditory cortex

Across sensory systems, complex spatio-temporal patterns of neural activity arise following the onset (ON) and offset (OFF) of stimuli. While ON responses have been widely studied, the mechanisms generating OFF responses in cortical areas h...

Applying Neural Networks: A Practical Guide

Techniques for building neural networks: introduction what are neural networks? how does neural computing differ from traditional programming? how are neural networks built? how do neural networks learn? what do I need to build an MLP? the ...

Incorporating structural plasticity into self-organization recurrent networks for sequence learning

IntroductionSpiking neural networks (SNNs), inspired by biological neural networks, have received a surge of interest due to its temporal encoding. Biological neural networks are driven by multiple plasticities, including spike timing-depen...

Humanized substitutions of Vmat1 in mice alter amygdala-dependent behaviors associated with the evolution of anxiety

Summary: The human vesicular monoamine transporter 1 (VMAT1) harbors unique substitutions (Asn136Thr/Ile) that affect monoamine uptake into synaptic vesicles. These substitutions are absent in all known mammals, suggesting their contributio...

Invariant representation of physical stability in the human brain

Successful engagement with the world requires the ability to predict what will happen next. Here, we investigate how the brain makes a fundamental prediction about the physical world: whether the situation in front of us is stable, and henc...

Tailoring Mission Effectiveness and Efficiency of a Ground Vehicle Using Exergy-Based Model Predictive Control (MPC)

To ensure dominance over a multi-domain battlespace, energy and power utilization must be accurately characterized for the dissimilar operational conditions. Using MATLAB/Simulink in combination with multiple neural networks, we created a m...

Deep Learning for Sensor-based Human Activity Recognition

The vast proliferation of sensor devices and Internet of Things enables the applications of sensor-based activity recognition. However, there exist substantial challenges that could influence the performance of the recognition system in pra...

Design of a TSR-based project learning strategy for biochemistry undergraduate teaching and research labs: a case study

Given the exponential growth of biochemical data and deep effect of computational methods on life sciences, there is a need to rethink undergraduate curricula. A project-oriented learning approach based on the Triangular Spatial Relationshi...

A Novel Methodology for Human Kinematics Motion Detection Based on Smartphones Sensor Data Using Artificial Intelligence

Kinematic motion detection aims to determine a person’s actions based on activity data. Human kinematic motion detection has many valuable applications in health care, such as health monitoring, preventing obesity, virtual reality, daily li...

Accuracy of machine learning for differentiation between optic neuropathies and pseudopapilledema

Abstract Background This study is to evaluate the accuracy of machine learning for differentiation between optic neuropathies, pseudopapilledema (PPE) and normals. Methods Two hundred and ninety-five images of optic neuropathies, 295 images...

The Glyco-Switch of life: O-GlcNAcylation in cell fate decision.

Fast reconstruction of SMS bSSFP myocardial perfusion images using noise map estimation network (NoiseMapNet): a head-to-head comparison with parallel imaging and iterative reconstruction

BackgroundSimultaneous multi-slice (SMS) bSSFP imaging enables stress myocardial perfusion imaging with high spatial resolution and increased spatial coverage. Standard parallel imaging techniques (e.g., TGRAPPA) can be used for image recon...

High-fidelity single-frame computational super-resolution using signal-preserving denoising-enabled deconvolution

Abstract Computational super-resolution (SR) methods enable nanoscale imaging from single-frame wide-field or spinning-disk confocal images without hardware modifications, yet face limitations: statistical restoration suffers from noise and...

Rethinking Gated Recurrent Units for Rotating Machinery Prognostics: A Physics-Consistency Benchmark on the Mismatch Between Gating Mechanisms and Degradation Dynamics

Rotating machinery prognostics is essential for ensuring the reliability and operational safety of industrial systems. Although gated recurrent units (GRUs) have achieved competitive performance in remaining useful life (RUL) prediction, wh...

Fairness in Deep Learning: A Computational Perspective

Fairness in deep learning has attracted tremendous attention recently, as deep learning is increasingly being used in high-stake decision making applications that affect individual lives. We provide a review covering recent progresses to ta...

A Survey of Deep Learning-Based Object Detection

Object detection is one of the most important and challenging branches of computer vision, which has been widely applied in people’s life, such as monitoring security, autonomous driving and so on, with the purpose of locating instances of ...

Deep learning microscopy

We demonstrate that a deep neural network can significantly improve optical microscopy, enhancing its spatial resolution over a large field-of-view and depth-of-field. After its training, the only input to this network is an image acquired ...

Deep Learning in Mining Biological Data

Recent technological advancements in data acquisition tools allowed life scientists to acquire multimodal data from different biological application domains. Categorized in three broad types (i.e. images, signals, and sequences), these data...

DeepPROTACs is a deep learning-based targeted degradation predictor for PROTACs

The rational design of PROTACs is difficult due to their obscure structure-activity relationship. Here the authors present a deep neural network model - DeepPROTACs - for predicting the degradation capacity of a proposed PROTAC molecule....

Contour-Based Wild Animal Instance Segmentation Using a Few-Shot Detector

Camera traps are widely used in wildlife research, conservation, and management, and abundant images are acquired every day. Efficient real-time instance segmentation networks can help ecologists label and study wild animals. However, exist...