Academic Articles & Research Papers

Identification of immune-associated biomarkers of diabetes nephropathy tubulointerstitial injury based on machine learning: a bioinformatics multi-chip integrated analysis

Abstract Background Diabetic nephropathy (DN) is a major microvascular complication of diabetes and has become the leading cause of end-stage renal disease worldwide. A considerable number of DN patients have experienced irreversible end-st...

Virtual CT Myelography: A Patch-Based Machine Learning Model to Improve Intraspinal Soft Tissue Visualization on Unenhanced Dual-Energy Lumbar Spine CT

Background: Distinguishing between the spinal cord and cerebrospinal fluid (CSF) non-invasively on CT is challenging due to their similar mass densities. We hypothesize that patch-based machine learning applied to dual-energy CT can accurat...

A review of machine learning in obesity

Rich sources of obesity-related data arising from sensors, smartphone apps, electronic medical health records and insurance data can bring new insights for understanding, preventing and treating obesity. For such large datasets, machine lea...

Machine Learning and the Future of Cardiovascular Care

The role of physicians has always been to synthesize the data available to them to identify diagnostic patterns that guide treatment and follow response. Today, increasingly sophisticated machine learning algorithms may grow to support clin...

Development of Machine Learning Models to Predict Compressed Sward Height in Walloon Pastures Based on Sentinel-1, Sentinel-2 and Meteorological Data Using Multiple Data Transformations

Accurate information about the available standing biomass on pastures is critical for the adequate management of grazing and its promotion to farmers. In this paper, machine learning models are developed to predict available biomass express...

Knowledge-transfer learning for prediction of matrix metalloprotease substrate-cleavage sites

Abstract Matrix Metalloproteases (MMPs) are an important family of proteases that play crucial roles in key cellular and disease processes. Therefore, MMPs constitute important targets for drug design, development and delivery. Advanced pro...

Directional Gaussian Mixture Models of the Gut Microbiome Elucidate Microbial Spatial Structure

ABSTRACT The gut microbiome is spatially heterogeneous, with environmental niches contributing to the distribution and composition of microbial populations. A recently developed mapping technology, MaPS-seq, aims to characterize the spatial...

Fatigue Monitoring Through Wearables: A State-of-the-Art Review

The objective measurement of fatigue is of critical relevance in areas such as occupational health and safety as fatigue impairs cognitive and motor performance, thus reducing productivity and increasing the risk of injury. Wearable systems...

Leveraging Cloud Technology for Personalized Multiple Sclerosis Care: A Comprehensive Data Management and Visualization Approach

This project develops a cloud-based solution for securely managing clinical data and patient-reported outcomes (PROMs) for multiple sclerosis (MS) patients. Utilizing REDCap for data collection, we incorporated clinical outcomes and PROMs f...

Application of MRI-Based Radiomics in Preoperative Prediction of NF2 Alteration in Intracranial Meningiomas

PurposeThis study aimed to investigate the feasibility of predicting NF2 mutation status based on the MR radiomic analysis in patients with intracranial meningioma.MethodsThis retrospective study included 105 patients with meningiomas, incl...

MATCHA, a novel regional hydroclimate-chemical reanalysis: System description and evaluation

We present MATCHA (Model for Atmospheric Transport and Chemistry in Asia), a 17-year (2003–2019) regional hydroclimate-chemical reanalysis for Asia (58–140° E, 4– 40° N) at 12 km resolution. MATCHA couples the Weather Research and Forecasti...

Towards a physics informed digital twin to predict cerebral blood flow and cerebral vascular regulation

Abstract Cerebral blood flow is essential for brain function and is governed by cerebral perfusion pressure and physiological mechanisms collectively referred to as cerebral vascular regulation (CVR). Direct measurement of cerebral blood fl...

Prediction of Drug Targets for Specific Diseases Leveraging Gene Perturbation Data: A Machine Learning Approach

Identification of the correct targets is a key element for successful drug development. However, there are limited approaches for predicting drug targets for specific diseases using omics data, and few have leveraged expression profiles fro...

Use of machine learning algorithms to determine the relationship between air pollution and cognitive impairment in Taiwan

Air pollution has become a major global threat to human health. Urbanization and industrialization over the past few decades have increased the air pollution. Plausible connections have been made between air pollutants and dementia. This st...

Machine Learning in Enzyme Engineering

Abstract Enzyme engineering plays a central role in developing efficient biocatalysts for biotechnology, biomedicine, and life sciences. Apart from classical rational design and directed evolution approaches, machine learning methods have b...

Memristor Synapse—A Device-Level Critical Review

The memristor has long been known as a nonvolatile memory technology alternative and has recently been explored for neuromorphic computing, owing to its capability to mimic the synaptic plasticity of the human brain. The architecture of a m...

Analysis of EMC Factors on Electronic Devices Using PLS-SEM Method: A Case Study in Vietnam

Electronic equipment is indispensable in the industrial 4.0 era. Electromagnetic Compatibility issues with electronic devices are increasingly concerning. The phenomenon of electromagnetic field compatibility is getting higher and higher. T...

Applications of Machine Learning in Cancer Prediction and Prognosis

Machine learning is a branch of artificial intelligence that employs a variety of statistical, probabilistic and optimization techniques that allows computers to "learn" from past examples and to detect hard-to-discern patterns from large, ...

PosturAll: A Posture Assessment Software for Children

From an early age, people are exposed to risk factors that can lead to musculoskeletal disorders like low back pain, neck pain and scoliosis. Medical screenings at an early age might minimize their incidence. The study intends to improve a ...

How Machine Learning Will Transform Biomedicine