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Developing a Rational, Optimized Product of Centella asiatica for Examination in Clinical Trials: Real World Challenges

Kirsten M. Wright, Janis McFerrin, Armando Alcázar Magaña, Armando Alcázar Magaña et al. • Frontiers in Nutrition (2022)

Botanical products are frequently sold as dietary supplements and their use by the public is increasing in popularity. However, scientific evaluation of their medicinal benefits presents unique challenges due to their chemical complexity, i...

DOAJ Open Access (DOAJ) DOI: 10.3389/fnut.2021.799137

GIS-Based Geothermal Favorability Mapping and Geological Consistency Assessment in the Lower Kura Basin

Allahverdi Tagiyev, Elmir Karagozov, Mehriban Ismayilova, Lala Abdullayeva et al. • Energies (2026)

The Lower Kura Basin is a tectonically active sedimentary region of Azerbaijan where geological and hydrogeological conditions may favor geothermal fluid circulation. This study develops a Geographic Information Systems (GIS)-based multi-cr...

DOAJ Open Access (DOAJ) DOI: 10.3390/en19174061

Weighing and Prioritizing the Eight Principles of Integrated Health, Safety, Environment and Energy Management in Industries Covered by the Ministry of Industry, Mining and Trade

Rasoul Yarahmadi, Hamed Moridi, Ali Asghar Farshad, Fereshteh Taheri • Salāmat-i kār-i Īrān (2020)

Abstract: Aim and Background: Today, with the growth of different dimensions of sustainable development, managers at the organizational and governmental levels have become more and more interested in the components of sustainable developmen...

DOAJ Open Access (DOAJ)

Potential barriers in implementing the rural toilet retrofitting project: A qualitative study in Jiaozuo, China

Yuan Wang, Yueqi Zhu, Caiyun Qi, Lu Li • Frontiers in Public Health (2022)

BackgroundChina has launched a large “toilet revolution” in rural areas, but the results show that sanitation has not always been markedly improved. Few scholars have paid attention to this issue, and the list of the reasons is scattered an...

DOAJ Open Access (DOAJ) DOI: 10.3389/fpubh.2022.965150

Effects of Vitex trifolia L. leaf extracts and phytoconstituents on cytokine production in human U937 macrophages

Hai-Ning Wee, Soek-Ying Neo, Deepika Singh, Hui-Chuing Yew et al. • BMC Complementary Medicine and Therapies (2020)

Abstract Background Dysregulation of pro-inflammatory cytokines such as tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β) form the basis of immune-mediated inflammatory diseases. Vitex trifolia L. is a medicinal plant growing in co...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12906-020-02884-w

The Identification of a Novel Spider Toxin Peptide, Lycotoxin-Pa2a, with Antibacterial and Anti-Inflammatory Activities

Min Kyoung Shin, In-Wook Hwang, Bo-Young Jang, Kyung-Bin Bu et al. • Antibiotics (2023)

With the increasing challenge of controlling infectious diseases due to the emergence of antibiotic-resistant strains, the importance of discovering new antimicrobial agents is rapidly increasing. Animal venoms contain a variety of function...

DOAJ Open Access (DOAJ) DOI: 10.3390/antibiotics12121708

Contribution of the Science, the Technology and the Innovation of the Universidad de Oriente to the Local Economic Revitalizing

Victor Salvador Soulary–Carracedo, Raimundo Lora–Freyre • Anuario Facultad de Ciencias Económicas y Empresariales (2015)

The main objective of the research is to design a methodology to evaluate the contribution of the science, the technology and the innovation of universities to the local economic revitalizing. The scientific novelty resides in a sequence of...

DOAJ Open Access (DOAJ)

Efficient generation of P53 biallelic knockout Diannan miniature pigs via TALENs and somatic cell nuclear transfer

Youfeng Shen, Kaixiang Xu, Zaimei Yuan, Jianxiong Guo et al. • Journal of Translational Medicine (2017)

Abstract Background Pigs have many features that make them attractive as biomedical models for various diseases, including cancer. P53 is an important tumor suppressor gene that exerts a central role in protecting cells from oncogenic trans...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12967-017-1327-0

<i>Escherichia coli</i> Phylogenetic and Antimicrobial Pattern as an Indicator of Anthropogenic Impact on Threatened Freshwater Mussels

Simone Varandas, Conceição Fernandes, Edna Cabecinha, Sónia Gomes et al. • Antibiotics (2023)

Freshwater bivalves are widely used as accumulation indicators and monitoring tools for assessing contaminant effects on different levels of biological integration. This pilot study aimed to explore the phylogenetic diversity of Escherichia...

DOAJ Open Access (DOAJ) DOI: 10.3390/antibiotics12091401

Rural Community Engagement for Heritage Conservation and Adaptive Renewal

Glenn C. Sutter, Leah O'Malley, Tobias Sperlich • Journal of Community Engagement and Scholarship (2023)

Systems thinking can shed light on important relationships and conditions that affect community engagement activities. While robust tools like the community capitals framework and the sustainable livelihoods approach provide valuable contex...

DOAJ Open Access (DOAJ) DOI: 10.54656/jces.v15i2.497

Genetic Diversity and Population Genetic Structure of Endemic Schizothoracinae Fishes in the Upper Yellow River and Its Adjacent Waters

Xiu Feng, Xiaoling Wang, Ren Zhu, Yintao Jia et al. • Ecology and Evolution (2025)

ABSTRACT The endemic fishes in the upper Yellow River and its adjacent waters on the Qinghai‐Tibet Plateau are very sensitive and vulnerable to human activities and climate changes. However, the status of populations, such as genetic divers...

DOAJ Open Access (DOAJ) DOI: 10.1002/ece3.72813

The Status of University Business Schools Regarding Industry 4.0: From the Turkish Perspective

Tulay Ilhan-Nas, Aysegul Saglam, Tarhan Okan, Iskender Peker • SAGE Open (2024)

Industry 4.0, whose effects have been more and more noticeable in recent years, and the digital change it brings call for a new educational model that aligns university instructional processes and curricula with the demands of business. Thi...

DOAJ Open Access (DOAJ) DOI: 10.1177/21582440241236578

A rapid fingerprint positioning method based on deep convolutional neural network for MIMO-OFDM systems

Chenlin He, Xiaojun Wang, Jiyu Jiao, Yuhua Huang et al. • Urban Lifeline (2024)

Abstract The combination of fingerprint positioning and 5G (the 5th Generation Mobile Communication Technology) offers broader application prospects for indoor positioning technology, but also brings challenges in real-time performance. In ...

DOAJ Open Access (DOAJ) DOI: 10.1007/s44285-024-00021-4

Accessibility Assessment of Buildings Based on Multi-Source Spatial Data: Taking Wuhan as a Case Study

Xue Yang, Yanjia Cao, Anqi Wu, Mingqiang Guo et al. • ISPRS International Journal of Geo-Information (2021)

The question of whether each building of housing estate has equal access to nearby social service resources (e.g., public transportation service, catering, entertainment, etc.) is a major concern of citizens. This paper takes Wuhan as a cas...

DOAJ Open Access (DOAJ) DOI: 10.3390/ijgi10100701

Zoning Erosion Hazard and Sediment Estimation in Cham Gardalan basin (Ilam province) using the Revised Universal Soil Erosion Equation (RUSLE)

Saleh Arekhi, Shahram Barani, Somia Emadaddian • مخاطرات محیط طبیعی (1401)

Soil erosion is one of the environmental problems that pose a threat to natural resources, agriculture and the environment. Quantitative assessment of erosion and sediment using erosion and sediment estimation models is one of the solutions...

DOAJ Open Access (DOAJ) DOI: 10.22111/jneh.2022.39063.1822

Opportunities and challenges of smart technology for small independent fashion retailers: a reflexive thematic analysis using the technology-organization-environment framework

Hyo Jung Chang, Francine Bruess, Jo Woon Chong • Fashion and Textiles (2024)

Abstract Smart technology has become an increasingly prominent feature in the fashion apparel industry. However, small retailers still face challenges while trying to adopt such innovative smart technologies to increase consumer interaction...

DOAJ Open Access (DOAJ) DOI: 10.1186/s40691-024-00391-x