Academic Articles & Research Papers

Opportunities and obstacles for deep learning in biology and medicine

Deep learning describes a class of machine learning algorithms that are capable of combining raw inputs into layers of intermediate features. These algorithms have recently shown impressive results across a variety of domains. Biology and m...

Survey on deep learning for radiotherapy

A bibliometric study of social isolation and biomarkers of ageing.

A survey on deep learning in medical image analysis

Deep Learning and Its Applications in Biomedicine

Advances in biological and medical technologies have been providing us explosive volumes of biological and physiological data, such as medical images, electroencephalography, genomic and protein sequences. Learning from these data facilitat...

Comparing deep learning and pathologist quantification of cell-level PD-L1 expression in non-small cell lung cancer whole-slide images

Abstract Programmed death-ligand 1 (PD-L1) expression is currently used in the clinic to assess eligibility for immune-checkpoint inhibitors via the tumor proportion score (TPS), but its efficacy is limited by high interobserver variability...

Deep learning in optical metrology: a review

With the advances in scientific foundations and technological implementations, optical metrology has become versatile problem-solving backbones in manufacturing, fundamental research, and engineering applications, such as quality control, n...

Deep Learning in Cardiology

The medical field is creating large amount of data that physicians are unable to decipher and use efficiently. Moreover, rule-based expert systems are inefficient in solving complicated medical tasks or for creating insights using big data....

Applications of Deep Learning in Biomedicine

Increases in throughput and installed base of biomedical research equipment led to a massive accumulation of -omics data known to be highly variable, high-dimensional, and sourced from multiple often incompatible data platforms. While this ...

Deep Learning in Medical Image Analysis

This review covers computer-assisted analysis of images in the field of medical imaging. Recent advances in machine learning, especially with regard to deep learning, are helping to identify, classify, and quantify patterns in medical image...

Application of visual transformer in renal image analysis

Abstract Deep Self-Attention Network (Transformer) is an encoder–decoder architectural model that excels in establishing long-distance dependencies and is first applied in natural language processing. Due to its complementary nature with th...

Deep Learning for Biometrics

In the recent past, deep learning methods have demonstrated remarkable success for supervised learning tasks in multiple domains including computer vision, natural language processing, and speech processing. In this article, we investigate ...

Deep Learning for Health Informatics

With a massive influx of multimodality data, the role of data analytics in health informatics has grown rapidly in the last decade. This has also prompted increasing interests in the generation of analytical, data driven models based on mac...

Cauchy non-convex sparse feature selection method for the high-dimensional small-sample problem in motor imagery EEG decoding

IntroductionThe time, frequency, and space information of electroencephalogram (EEG) signals is crucial for motor imagery decoding. However, these temporal-frequency-spatial features are high-dimensional small-sample data, which poses signi...

Deep learning in biomedicine

Deep learning in bioinformatics

In the era of big data, transformation of biomedical big data into valuable knowledge has been one of the most important challenges in bioinformatics. Deep learning has advanced rapidly since the early 2000s and now demonstrates state-of-th...

Towards personalized and lifestyle-inspired soil management: lessons from the gut microbiome.

The Microbiome Composition of a Man's Penis Predicts Incident Bacterial Vaginosis in His Female Sex Partner With High Accuracy

Background: We determined the predictive accuracy of penile bacteria for incident BV in female sex partners. In this prospective cohort, we enrolled Kenyan men aged 18–35 and their female sex partners aged 16 and older. We assessed BV at ba...

Integrative multiomics analysis of platelet-related genes unveils molecular subtypes and prognostic signatures in acute myeloid leukemia

Abstract Acute myeloid leukemia (AML) remains challenging due to molecular heterogeneity and limited prognostic models integrating tumor microenvironment dynamics. While thrombocytopenia correlates with poor outcomes, the roles of platelet-...

Increased Atmospheric Aridity and Reduced Precipitation Drive the 2023 Extreme Wildfire Season in Canada

Abstract Canada experienced an unprecedented wildfire season in 2023. Here, we analyzed the exceptional scale, dominant driving factors, and potential impacts on permafrost of these wildfires using Moderate Resolution Imaging Spectroradiome...