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A brief review of Lynch syndrome: understanding the dual cancer risk between endometrial and colorectal cancer

Sneha Pallatt, Sibin Nambidi, Subhamay Adhikary, Antara Banerjee et al. • Oncology Reviews (2025)

Lynch syndrome (LS) is an autosomal dominant disorder caused by germline mutations in DNA mismatch repair (MMR) genes. These mutations result in frameshift alterations, leading to the accumulation of errors within microsatellites. Individua...

DOAJ Open Access (DOAJ) DOI: 10.3389/or.2025.1549416

Emerging mutations in envelope protein of SARS-CoV-2 and their effect on thermodynamic properties

Kejie Mou, Mohnad Abdalla, Dong Qing Wei, Muhammad Tahir Khan et al. • Informatics in Medicine Unlocked (2021)

Structural proteins of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are potential drug targets due to their role in the virus life cycle. The envelope (E) protein is one of the structural proteins; plays a critical role in v...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.imu.2021.100675

Data supporting the angiotensin II activates MEL18 to deSUMOylate HSF2 for hypertension-related heart failure

Chih-Yang Huang, Chia-Hua Kuo, Pei-Ying Pai, Tsung-Jung Ho et al. • Data in Brief (2018)

In association with the published article “Inhibition of HSF2 SUMOylation via MEL18 upregulates IGF-IIR and leads to hypertension-induced cardiac hypertrophy” (Huang et al., 2017) [1], this data article contains information about deSUMOylat...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.dib.2017.11.040

The Advancement of Medical Biotechnology in Developing Countries: Economic Opportunities and Challenges

Jiawen Chen • Highlights in Business Economics and Management (2023)

Starting from decades ago, medical biotechnology has revolutionized the healthcare industry by offering new hopes for previously untreatable diseases and improving overall health outcomes. To explore the advancements in medical biotechnolog...

OPENALEX cc-by-nc DOI: https://doi.org/10.54097/45c92q28

Reimbursement Legislations and Decision Making for Orphan Drugs in Central and Eastern European Countries

Krzysztof Piotr Malinowski, Paweł Kawalec, Wojciech Trąbka, Marcin Czech et al. • Frontiers in Pharmacology (2019)

BackgroundReimbursement policies influence access of patients to orphan drugs in the European countries.ObjectivesTo provide a comprehensive description of orphan drug reimbursement policies and to assess reimbursement decision-making proce...

DOAJ Open Access (DOAJ) DOI: 10.3389/fphar.2019.00487

Deregulated miRNA clusters in ovarian cancer: Imperative implications in personalized medicine

Amoolya Kandettu, Divya Adiga, Vasudha Devi, Padmanaban S. Suresh et al. • Genes and Diseases (2022)

Ovarian cancer (OC) is one of the most common and fatal types of gynecological cancer. OC is usually detected at the advanced stages of the disease, making it highly lethal. miRNAs are single-stranded, small non-coding RNAs with an approxim...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.gendis.2021.12.026

Expanding the genetic spectrum of hereditary motor sensory neuropathies in Pakistan

Asif Naveed Ahmed, Lettie E. Rawlins, Niamat Khan, Zakir Jan et al. • BMC Neurology (2024)

Abstract Background Hereditary motor and sensory neuropathy (HMSN) refers to a group of inherited progressive peripheral neuropathies characterized by reduced nerve conduction velocity with chronic segmental demyelination and/or axonal dege...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12883-024-03882-y

Relationship between Perceived Social Support in First Pregnancy with Birth Satisfaction in Primigravid Women Referred to Shahid Akbar Abadi Hospital

homa sadeghi aval shahr, sayeh sadat moosavi sahebalzamani, freshteh jahdi, leila neisani samani et al. • Preventive Care in Nursing and Midwifery Journal (2014)

Background and Objectives: Recent studies have shown that social and environmental factors as well as social communication play crucial role in pregnancy outcomes. The current study aimed to examine the relationship between perceived social...

DOAJ Open Access (DOAJ)

How Does the Diversity of Divers Affect the Design of Citizen Science Projects?

María I. Hermoso, María I. Hermoso, Victoria Y. Martin, Wolfgang Stotz et al. • Frontiers in Marine Science (2019)

Divers have widely participated in citizen science (CS) projects and are one of the main groups of marine citizen scientists. However, there is little knowledge about profiles of, and incentives for potential divers to join CS projects. To ...

DOAJ Open Access (DOAJ) DOI: 10.3389/fmars.2019.00239

Impact of patient-centered communication on patient satisfaction scores in patients with chronic life-limiting illnesses: an experience from Kenya

Betty Sirera, Violet Naanyu, Peter Kussin, David Lagat • Frontiers in Medicine (2024)

BackgroundPatient satisfaction remains a key area of interest worldwide; utilizing a patient-centered communication approach, particularly with patients with chronic life-limiting illnesses may be one way to achieve this. However, there is ...

DOAJ Open Access (DOAJ) DOI: 10.3389/fmed.2024.1290907

Social Media Listening to Understand the Lived Experience of Individuals in Europe With Metastatic Breast Cancer: A Systematic Search and Content Analysis Study

Manuelita Mazza, Maria Piperis, Sathyaraj Aasaithambi, Jyoti Chauhan et al. • Frontiers in Oncology (2022)

BackgroundDespite a wealth of real-world data on metastatic breast cancer (mBC), insights into the lived experience are lacking. This study aimed to explore how the lived experience of mBC is described on social media.MethodsA predefined se...

DOAJ Open Access (DOAJ) DOI: 10.3389/fonc.2022.863641

Consumers perception on green marketing towards eco-friendly fast moving consumer goods

K Pradeep Reddy, Venkateswarlu Chandu, Sambhana Srilakshmi, Elia Thagaram et al. • International Journal of Engineering Business Management (2023)

In today’s commercial world, ecological concerns have become increasingly essential. A lot of governments care about environmental issues. Sustainable development that doesn’t harm the environment is a major concern for companies today. The...

DOAJ Open Access (DOAJ) DOI: 10.1177/18479790231170962

Full-scale simulations to improve disaster preparedness in hospital pharmacies

Laurence Schumacher, Salim Senhaji, Birgit Andrea Gartner, Laurent Carrez et al. • BMC Health Services Research (2022)

Abstract Purpose Assess whether full-scale simulation exercises improved hospital pharmacies’ disaster preparedness. Methods Swiss hospital pharmacies performed successive full-scale simulation exercises at least four months apart. An inter...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12913-022-08230-9

Disciplining Organizational Communication Studies

Dennis K. Mumby, Cynthia Stohl • Management Communication Quarterly (1996)

The authors argue that, although ostensibly organizational communication as a field of study appears fragmented, one can make the case for its status as a discipline. This status is rooted in four central problematics that implicitly frame ...

OPENALEX DOI: https://doi.org/10.1177/0893318996010001004