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A New Strategy for Efficient Screening and Identification of Monoclonal Antibodies against Oncogenic Avian Herpesvirus Utilizing CRISPR/Cas9-Based Gene-Editing Technology

Man Teng, Zi-Yu Zhou, Yongxiu Yao, Venugopal Nair et al. • Viruses (2022)

Marek’s disease virus (MDV) is an important oncogenic α-herpesvirus that induces Marek’s disease (MD), characterized by severe immunosuppression and rapid-onset T-cell lymphomas in its natural chicken hosts. Historically, MD is regarded as ...

DOAJ Open Access (DOAJ) DOI: 10.3390/v14092045

How <i>Phytophthora</i> Effectors Disrupt Post-Translational Regulation in Plant Immunity: Canonical and Non-Canonical Mechanisms

Gilberto Muñoz-Pérez, Fátima Álvarez-Camarena, Julio Vega-Arreguin • Kinases and Phosphatases (2026)

Plant–pathogen interactions are shaped by dynamic regulatory processes that control immune signaling. Among these, post-translational modifications (PTMs) play central roles in modulating protein activity, stability, and interaction network...

DOAJ Open Access (DOAJ) DOI: 10.3390/kinasesphosphatases4020011

Genetic and Psychosocial Risk Factors Associated with Suicide Among Community Veterans: Implications for Screening, Treatment and Precision Medicine

Boscarino JA, Adams RE, Urosevich TG, Hoffman SN et al. • Pharmacogenomics and Personalized Medicine (2022)

Joseph A Boscarino,1 Richard E Adams,2 Thomas G Urosevich,3 Stuart N Hoffman,4 H Lester Kirchner,1 Xin Chu,5 Weixing Shi,5 Joseph J Boscarino,6 Ryan J Dugan,1 Carrie A Withey,1 Charles R Figley7 1Department Population Health Sciences, Geisi...

DOAJ Open Access (DOAJ)

Behavior Responses to Chemical and Optogenetic Stimuli in Drosophila Larvae

David A. Clark, David A. Clark, Seth R. Odell, Seth R. Odell et al. • Frontiers in Behavioral Neuroscience (2018)

An animal’s ability to navigate an olfactory environment is critically dependent on the activities of its first-order olfactory receptor neurons (ORNs). While considerable research has focused on ORN responses to odorants, the mechanisms by...

DOAJ Open Access (DOAJ) DOI: 10.3389/fnbeh.2018.00324

Small cell neuroendocrine carcinoma of the cervix: From molecular basis to therapeutic advances

Angel Chao, Ren-Chin Wu, Chiao-Yun Lin, Ting-Chang Chang et al. • Biomedical Journal (2023)

Small cell neuroendocrine carcinoma of the cervix (SCNECC) is an uncommon but aggressive uterine malignancy, the cause of which is generally associated with human papillomavirus (HPV) infection. A lack of clinical trials and evidence-based ...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.bj.2023.100633

Meta-analysis of MitraClip and PASCAL for transcatheter mitral edge-to-edge repair

Mahmoud Balata, Mohamed Ibrahim Gbreel, Mohamed Hamouda Elkasaby, Marwa Hassan et al. • Journal of Cardiothoracic Surgery (2025)

Abstract Background Despite the promising results of both MitraClip and PASCAL systems for the treatment of mitral regurgitation (MR), there is limited data on the comparison of both systems regarding their safety and efficacy. We aim to co...

DOAJ Open Access (DOAJ) DOI: 10.1186/s13019-024-03218-4

Current Trends in Tolerance Induction in Cow's Milk Allergy: From Passive to Proactive Strategies

Cansin Sackesen, Derya Ufuk Altintas, Aysen Bingol, Gulbin Bingol et al. • Frontiers in Pediatrics (2019)

This review addresses the current strategies of inducing tolerance development in infant and childhood cow's milk protein allergy (CMPA). The change in prevention strategies for CMPA has been emphasized based on the lack of evidence to supp...

DOAJ Open Access (DOAJ) DOI: 10.3389/fped.2019.00372

Interacting roles of gut microbiota and T cells in the development of autoimmune hepatitis

Qingwei Wu, Zhifa Ge, Chengyu Lv, Qifeng He • Frontiers in Immunology (2025)

Autoimmune hepatitis (AIH) is a progressive liver inflammatory disease mediated by an autoimmune response, with an increasing incidence rate. In severe cases, AIH will rapidly progress to liver cirrhosis and liver failure and even lead to d...

DOAJ Open Access (DOAJ) DOI: 10.3389/fimmu.2025.1584001

Genetic Markers of Adaptation of <named-content content-type="genus-species">Plasmodium falciparum</named-content> to Transmission by American Vectors Identified in the Genomes of Parasites from Haiti and South America

Massimiliano S. Tagliamonte, Charles A. Yowell, Maha A. Elbadry, Jacques Boncy et al. • mSphere (2020)

ABSTRACT The malaria parasite, Plasmodium falciparum, was introduced into Hispaniola and other regions of the Americas through the slave trade spanning the 16th through the 19th centuries. During this period, more than 12 million Africans w...

DOAJ Open Access (DOAJ) DOI: 10.1128/mSphere.00937-20

Exploring innovation landscapes: a national cross-sectional study of Swedish primary care from the viewpoint of primary care managers

Sarah Samuelson, Eva-Lisa Petersson, Cecilia Björkelund, Marcus Praetorius Björk et al. • BMC Health Services Research (2026)

Abstract Background Innovation is increasingly necessary in primary care policy, and healthcare managers play a pivotal role in translating policy ambitions into practice and shaping organisational conditions that foster innovation. The aim...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12913-026-14870-y

The effect of science centres on perceptions of secondary school students towards the nature of science

Hacer Efe, Ünsal Umdu Topsakal • South African Journal of Education (2022)

In the study reported on here, the effects of science centres on the perceptions of secondary school students towards the nature of science were examined. The study group consisted of 16 students aged 13 and 14 of which 7 were female and 9 ...

DOAJ Open Access (DOAJ) DOI: 10.15700/saje.v42n2a2017

The JWST Resolved Stellar Populations Early Release Science Program. VIII. The Spatially Resolved Star Formation History of WLM

Roger E. Cohen, Kristen B. W. McQuinn, Alessandro Savino, Max J. B. Newman et al. • The Astrophysical Journal (2025)

Radial stellar population gradients within dwarf galaxies provide a promising avenue for disentangling the drivers of galaxy evolution, including environment. Within the Local Volume, radial stellar age gradient slopes correlate with intera...

DOAJ Open Access (DOAJ) DOI: 10.3847/1538-4357/adb61d

Utilization of mobile health applications and determinant factors among health science students at Debre Markos University, northwest Ethiopia in 2022.

Gizaw Hailiye Teferi, Maru Meseret Tadele, Getaye Tizazu, Zegeye Regasa Hordofa et al. • PLoS ONE (2023)

BackgroundHigh penetration of smartphones and ownership among the young generation increased the utilization of mobile health applications for health management among university students more than ever. Compared to other health service prov...

DOAJ Open Access (DOAJ) DOI: 10.1371/journal.pone.0275689

Spatial patterns in the contribution of biotic and abiotic factors to the population dynamics of three freshwater fish species

Mathieu Chevalier, Pablo Tedesco, Gael Grenouillet • PeerJ (2022)

Background Population dynamics are driven by a number of biotic (e.g., density-dependence) and abiotic (e.g., climate) factors whose contribution can greatly vary across study systems (i.e., populations). Yet, the extent to which the contri...

DOAJ Open Access (DOAJ) DOI: 10.7717/peerj.12857

Genomic Organization and Expression of Iron Metabolism Genes in the Emerging Pathogenic Mold Scedosporium apiospermum

Yohann Le Govic, Yohann Le Govic, Nicolas Papon, Solène Le Gal et al. • Frontiers in Microbiology (2018)

The ubiquitous mold Scedosporium apiospermum is increasingly recognized as an emerging pathogen, especially among patients with underlying disorders such as immunodeficiency or cystic fibrosis (CF). Indeed, it ranks the second among the fil...

DOAJ Open Access (DOAJ) DOI: 10.3389/fmicb.2018.00827

Empowering Students for Cybersecurity Awareness Management in the Emerging Digital Era: The Role of Cybersecurity Attitude in the 4.0 Industrial Revolution Era

Bulbul Ahamed, Mohammad Rashed Hasan Polas, Ahmed Imran Kabir, Abu Saleh Md. Sohel-Uz-Zaman et al. • SAGE Open (2024)

The purpose of the study is to examine how cybersecurity knowledge, password security, and self-perception of skill affect cybersecurity awareness issues via the mediating lens of cybersecurity attitude among university students in Banglade...

DOAJ Open Access (DOAJ) DOI: 10.1177/21582440241228920

TransKGQA: Enhanced Knowledge Graph Question Answering With Sentence Transformers

You Li Chong, Chin Poo Lee, Shahrin Zen Muhd-Yassin, Kian Ming Lim et al. • IEEE Access (2024)

Knowledge Graph Question Answering (KGQA) plays a crucial role in extracting valuable insights from interconnected information. Existing methods, while commendable, face challenges such as contextual ambiguity and limited adaptability to di...

DOAJ Open Access (DOAJ) DOI: 10.1109/ACCESS.2024.3405583