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Academic Articles & Research Papers
Showing 20 of 284 academic articles
Zhi Zheng, Yunkuo Li, Yujie Pan • Cell Death Discovery
(2026)
Abstract Diabetic kidney disease (DKD), a prevalent microvascular complication of diabetes, is a leading cause of chronic kidney disease and end-stage renal disease. Moreover, it plays a crucial role in the morbidity and mortality of diabet...
DOAJ
Open Access (DOAJ)
DOI: 10.1038/s41420-026-03117-8
Jia-Huan Shang, Wen-Jie Sun, Hong-Tao Zhu, Dong Wang et al. • Journal of Ginseng Research
(2020)
Background: Root rot is a serious destructive disease of Panax notoginseng, a famous cultivated araliaceous herb called Sanqi or Tianqi in Southwest China. Methods: The chemical substances of Sanqi rot roots were explored by chromatographic...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.jgr.2019.01.008
Mahadevaswamy G. Kuruburu, Venugopal R. Bovilla, Rimshia Naaz, Zonunsiami Leihang et al. • Frontiers in Pharmacology
(2026)
Epidemiological studies have demonstrated an inverse correlation between millet-based diets and incidence of cancers of colon and rectum. These findings highlight the potential of millets as functional foods for effective management of canc...
DOAJ
Open Access (DOAJ)
DOI: 10.3389/fphar.2026.1805287
Linping Hui, Siyang Zhang, Muli Wudu, Hongjiu Ren et al. • Thoracic Cancer
(2019)
Background Studies have shown that E3 ubiquitin ligase CBLL1 plays multiple roles in development and tumorigenesis. CBLL1 is over‐expressed in colon cancer and associated with cancer cell proliferation. While, the overexpression of CBLL1 in...
DOAJ
Open Access (DOAJ)
DOI: 10.1111/1759-7714.13097
Sofia Leonardo, Felipe Fregni • Frontiers in Aging Neuroscience
(2023)
BackgroundThe development of mild cognitive impairment (MCI) and Alzheimer’s disease (AD) may be associated with an inflammatory process. Inflammatory cytokines may be a surrogate for systemic inflammation leading to worsening neurological ...
DOAJ
Open Access (DOAJ)
DOI: 10.3389/fnagi.2023.1069439
Yashaswini Reddy, Gargi Joshi, Swechha Mahapatra, Ipshita Das et al. • Journal of Genetic Engineering and Biotechnology
(2026)
RECQ helicases involve a family of DNA unwinding enzymes, namely, RECQ1, Bloom syndrome protein, Werner syndrome protein, RECQL4, and RECQ5. These proteins interact with various proteins to form complexes and carry out a range of physiologi...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.jgeb.2026.100824
Juan Carlos Lopez-Baez, Daniel J Simpson, Laura LLeras Forero, Zhiqiang Zeng et al. • eLife
(2018)
Regenerative therapy for degenerative spine disorders requires the identification of cells that can slow down and possibly reverse degenerative processes. Here, we identify an unanticipated wound-specific notochord sheath cell subpopulation...
DOAJ
Open Access (DOAJ)
DOI: 10.7554/eLife.30657
Yuxiong Lu, Junichi Maruyama, Keiko Kuwata, Hiroyuki Fukuda et al. • Biochemistry and Biophysics Reports
(2018)
Doublecortin-like kinase 1 (DCLK1) is a serine/threonine-kinase with two doublecortin (DCX) domains. DCLK1 is associated with microtubules via DCX domains and regulates microtubule polymerization. DCLK1 is known to be expressed in cancer st...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.bbrep.2018.10.014
Yi-Lei Zhang, Ruo-Chen Wang, Ken Cheng, Brian Z. Ring et al. • Cancer Biology & Medicine
(2017)
Ras-associated protein-1 (Rap1), a small GTPase in the Ras-related protein family, is an important regulator of basic cellular functions (e.g., formation and control of cell adhesions and junctions), cellular migration, and polarization. Th...
DOAJ
Open Access (DOAJ)
DOI: 10.20892/j.issn.2095-3941.2016.0086
Saul Vislei Simões da Silva, Orlando Maia Barboza, Jéssica Teles Souza, Érica Novaes Soares et al. • Molecules
(2021)
Quercetin (Q) is a bioflavonoid with biological potential; however, poor solubility in water, extensive enzymatic metabolism and a reduced bioavailability limit its biopharmacological use. The aim of this study was to perform structural mod...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/molecules26226923
Li Rong, Haiyu Li, Zhaodong Li, Jing Ouyang et al. • Frontiers in Medicine
(2020)
Background and Objective: Chemotherapy and radiotherapy are effective treatment options for cervical cancer (CC), but their efficacy is limited by short survival rate of about 5 years particularly for advance stage CC. Bioinformatics analys...
DOAJ
Open Access (DOAJ)
DOI: 10.3389/fmed.2020.608441
Jing Yang, Pengfei Li, Pengfei Li, Pengfei Li et al. • Frontiers in Immunology
(2022)
ObjectiveExtranodal natural killer/T cell lymphoma (NKTCL) is an aggressive EBV-related lymphoma, originating from NK cells or T cells. Previous study demonstrated that CD56 negative NKTCL should be recognized as a distinct subtype. In this...
DOAJ
Open Access (DOAJ)
DOI: 10.3389/fimmu.2022.829366
Qiang Wang, Qiang Wang, Yujun Ji, Torkel B. Brismar et al. • Frontiers in Surgery
(2021)
Background: To evaluate the feasibility and efficacy of sequential portal vein embolization (PVE) and radiofrequency ablation (RFA) (PVE+RFA) as a minimally invasive variant for associating liver partition and portal vein ligation for stage...
DOAJ
Open Access (DOAJ)
DOI: 10.3389/fsurg.2021.741352
Alkhateeb A, Mahmoud HEM, AK M, Hassan MH et al. • Vascular Health and Risk Management
(2023)
Areej Alkhateeb,1 Hossam Eldin M Mahmoud,1 Mohammed AK,1 Mohammed H Hassan,2 Abdel Rahim Mahmoud Muddathir,3 Ahmed G Bakry1 1Cardiology Division of Internal Medicine Department, South Valley University Hospital, Faculty of Medicine, South V...
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Open Access (DOAJ)
Senyefia Bosson-Amedenu, Emmanuel Ayitey, Francis Ayiah-Mensah, Luyton Asare • BMC Cancer
(2025)
Abstract Background Frailty models are extensively utilized in survival analysis to address unobserved heterogeneity among individuals. However, selecting the most robust model for survival prediction, especially in the context of high-dime...
DOAJ
Open Access (DOAJ)
DOI: 10.1186/s12885-025-14040-z
Sipeng Shen, Ruyang Zhang, Yue Jiang, Yi Li et al. • Molecular Cancer
(2021)
Abstract N6-Methyladenosine (m6A) is an RNA modification that interacts with numerous coding and non-coding RNAs and plays important roles in the development of cancers. Nonetheless, the clinical impacts of m6A interactive genes on these ca...
DOAJ
Open Access (DOAJ)
DOI: 10.1186/s12943-021-01362-2
Wei Liao, PhD, Meredith Ray, PhD, Carrie Fehnel, BBA, Jordan Goss, MA et al. • JTO Clinical and Research Reports
(2024)
Introduction: Low-dose computed tomography screening (LDCT) and lung nodule programs (LNP) promote early lung cancer detection, improve survival; Multidisciplinary Care Programs (MDC) promote guideline-concordant care. The impact of such pr...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.jtocrr.2023.100629
Orlando Ricaurte, Karina Neita, Danyela Valero, Jenny Ortega-Rojas et al. • Biomédica: revista del Instituto Nacional de Salud
(2018)
Introduction: Gliomas are the most common primary tumors of the central nervous system and, according to their malignancy, they are graded from I to IV. Recent studies have found that there is an association between gliomas and mutations in...
DOAJ
Open Access (DOAJ)
DOI: 10.7705/biomedica.v38i0.3708
Walla Malkawi, Areeb Lutfi, Maaz Khan Afghan, Lamisha Mashiyat Shah et al. • Frontiers in Oncology
(2023)
ObjectiveMost of the work in terms of liquid biopsies in patients with solid tumors is focused on circulating tumor DNA (ctDNA). Our aim was to evaluate the feasibility of using circulating tumor cells (CTCs) in peripheral blood samples fro...
DOAJ
Open Access (DOAJ)
DOI: 10.3389/fonc.2023.1305181
Choon Chiat Oh, Boon Yee Lim, Elizabeth Chun Yong Lee, Bavani Kannan et al. • JEADV Clinical Practice
(2025)
ABSTRACT Background Cutaneous squamous cell carcinoma (cSCC) remains poorly understood at the molecular level, both in the immunocompetent and immunosuppressed population with skin of colour. Data on the diversity of viruses found in cSCC i...
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Open Access (DOAJ)
DOI: 10.1002/jvc2.70142