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Effects of individualized rTMS on functional connectivity related to the default mode network and frontal-parietal network in major depressive disorder: exploratory analysis of a randomized controlled trial

Jing Jin, Yun Wang, Sixiang Liang, Qingchen Fan et al. • NeuroImage: Clinical (2025)

Objective: Repetitive transcranial magnetic stimulation (rTMS) has been shown to alleviate depressive and anxiety symptoms in patients with major depressive disorder (MDD), typically by targeting the dorsolateral (DLPFC) or dorsomedial pref...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.nicl.2025.103902

On the correspondence between the transcriptomic response of a compound and its effects on its targets

Chloe Engler Hart, Daniel Ence, David Healey, Daniel Domingo-Fernández • BMC Bioinformatics (2023)

Abstract Better understanding the transcriptomic response produced by a compound perturbing its targets can shed light on the underlying biological processes regulated by the compound. However, establishing the relationship between the indu...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12859-023-05337-6

Identifying urban features for vulnerable road user safety in Europe

Marina Klanjčić, Laetitia Gauvin, Michele Tizzoni, Michael Szell • EPJ Data Science (2022)

Abstract One of the targets of the UN Sustainable Development Goals is to substantially reduce the number of global deaths and injuries from road traffic collisions. To this aim, European cities adopted various urban mobility policies, whic...

DOAJ Open Access (DOAJ) DOI: 10.1140/epjds/s13688-022-00339-5

Healthcare Management and the Humanities: An Invitation to Dialogue

Nathan M. Gerard • International Journal of Environmental Research and Public Health (2021)

Throughout the fields of medicine and organization studies, there are growing indications of the value of the humanities for enriching scholarship, education, and practice. However, the field of healthcare management has yet to consider the...

OPENALEX cc-by DOI: https://doi.org/10.3390/ijerph18136771 PMC: 8296922

Emerging mutations in envelope protein of SARS-CoV-2 and their effect on thermodynamic properties

Kejie Mou, Mohnad Abdalla, Dong Qing Wei, Muhammad Tahir Khan et al. • Informatics in Medicine Unlocked (2021)

Structural proteins of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are potential drug targets due to their role in the virus life cycle. The envelope (E) protein is one of the structural proteins; plays a critical role in v...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.imu.2021.100675

Computational Tools; Indispensable Armamentarium of Medical Biotechnology

Nutan, Swapnil Jain, K Shilpa, Akanksha Tomar et al. • Indian Journal of Science and Technology (2016)

Objective: Computational infrastructure of medical biotechnology provides insight into elements of genomics, proteomics for understanding diseases and biological systems in a more comprehensive and systematic way. The present study exclusiv...

OPENALEX cc-by DOI: https://doi.org/10.17485/ijst/2016/v9i32/100745

SIRT1 and miR-34a as Potential Plasma Biomarkers in the Acute Phase of Ischemic Stroke

Mitra Ansari, Moslem Esmati, Seyed khalil Rashidi, Shahram Rafie et al. • International Journal of Molecular and Cellular Medicine (2025)

Stroke is the major cause of disability and mortality worldwide. Identification of molecular biomarkers in the early hours after stroke is important in terms of both diagnostic and therapeutic applications. miR-34a, a highly expressed miRNA...

DOAJ Open Access (DOAJ)

Isolation, characterization, and genomic analysis of a novel phage WSPA with lytic activity against Serratia marcescens

Lijuan Li, Kunkun Li, Yu Mi, Xiumei Wu et al. • Microbiology Spectrum (2025)

ABSTRACT Serratia marcescens is an established pathogen implicated in hospital-acquired infections and is notorious for its propensity to form biofilms on medical devices, leading to persistent environmental contamination and increased infe...

DOAJ Open Access (DOAJ) DOI: 10.1128/spectrum.02716-24

Current Evidence on Gene-Based and Epigenetic Therapeutic, Diagnostic, and Prognostic Strategies in Epithelial-Derived Carcinomas: A Scoping Review

Joshua George Thomas, Mohammed Ayyub, Lovely M. Annamma, Prathibha Prasad et al. • Biomedicines (2026)

Background: Epithelial-derived carcinomas exhibit genomic instability due to genetic mutation and epigenetic dysregulation. Mechanisms such as DNA methylation, histone modifications, and noncoding RNA regulation may lead to tumor progressio...

DOAJ Open Access (DOAJ) DOI: 10.3390/biomedicines14102234

KRAS G12V neoantigen specific T cell receptor for adoptive T cell therapy against tumors

Dan Lu, Yuan Chen, Min Jiang, Jie Wang et al. • Nature Communications (2023)

Abstract KRAS mutations are broadly recognized as promising targets for tumor therapy. T cell receptors (TCRs) can specifically recognize KRAS mutant neoantigens presented by human lymphocyte antigen (HLA) and mediate T cell responses to el...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41467-023-42010-1

Integrated crop-livestock-forest systems: a path to improved agro-economic performance in the Brazilian Amazon and Cerrado

Julio Cesar dos Reis, Mariana Yumi Takahashi Kamoi, Tarik Marques do Prado Tanure, Maisa Isabela Rodrigues et al. • Frontiers in Sustainable Food Systems (2025)

Diversified sustainable agricultural systems, such as integrated crop-livestock-forest systems (ICLFs), offer substantial potential for enhancing food production to meet the increasing global demand for agricultural goods while, simultaneou...

DOAJ Open Access (DOAJ) DOI: 10.3389/fsufs.2025.1518747

A New Golden Age? Proposal for an Innovative Global Health Funding Mechanism for Middle‐Income Countries

Claire Chaumont, Jenny Hsi, Christine Bohne, Sana Mostaghim et al. • Global Challenges (2017)

Abstract Despite economic growth and increased global commitment to health financing in the past decades, the health needs of some of the world's most vulnerable people remain overlooked. In particular, middle‐income countries (MICs) often ...

DOAJ Open Access (DOAJ) DOI: 10.1002/gch2.201700015

Lipid remodeling enhances heat tolerance in rose via α-linolenic acid and jasmonate accumulation

Jian Li, He-Nan Bao, Ke-Yu Li, Zhi Wen et al. • Industrial Crops and Products (2026)

The rose, often referred to as the queen of flowers, is one of the four primary cut flowers; however, its growth is susceptible to high-temperature stress. Furthermore, with the advent of global warming, extreme high temperatures are becomi...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.indcrop.2026.122958

Asteroseismology of the Nearby K Dwarf σ Draconis Using the Keck Planet Finder and TESS

Marc Hon, Daniel Huber, Yaguang Li, Travis S. Metcalfe et al. • The Astrophysical Journal (2024)

Asteroseismology of dwarf stars cooler than the Sun is very challenging owing to the low amplitudes and rapid timescales of oscillations. Here we present the asteroseismic detection of solar-like oscillations at 4-minute timescales ( ${\nu ...

DOAJ Open Access (DOAJ) DOI: 10.3847/1538-4357/ad76a9

Seroprevalence and risk factors of porcine cysticercosis in Mpwapwa district, eastern-Central Tanzania

Justine Daudi Maganira, Noel Mark Makwinya, Beda John Mwang'onde • Parasite Epidemiology and Control (2025)

Porcine cysticercosis, caused by the larval stage of Taenia species, poses significant health and economic challenges in low and lower-middle-income regions. This study assessed the seroprevalence and risk factors associated with the transm...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.parepi.2025.e00445

Epigenetic Mechanisms and Nephrotic Syndrome: A Systematic Review

Samantha Hayward, Kevon Parmesar, Gavin I. Welsh, Matthew Suderman et al. • Biomedicines (2023)

A small subset of people with nephrotic syndrome (NS) have genetically driven disease. However, the disease mechanisms for the remaining majority are unknown. Epigenetic marks are reversible but stable regulators of gene expression with uti...

DOAJ Open Access (DOAJ) DOI: 10.3390/biomedicines11020514