Academic Articles & Research Papers

The Role of Mast Cells and Their Potential as a Therapeutic Target For Neuroinflammation

Sarah Adriana Scuderi,1 Rossella Basilotta,2 Laura Cucinotta,2 Alessio Ardizzone,3 Emanuela Esposito21Genetics and Pharmacogenetics Unit, ‘Gaetano Martino’ University Hospital, Messina, Italy; 2Department of Chemical, Biological, Pharmaceut...

Avocado Oil Nanoemulsion Ameliorates STZ-Induced Diabetic Brain Dysfunction through PI3K/AKT/mTOR-Related Gene Modulation and Attenuation of Apoptosis.

Targeting Inflammation With Nanosized Drug Delivery Platforms in Cardiovascular Diseases: Immune Cell Modulation in Atherosclerosis

Atherosclerosis (AS) is a disorder of large and medium-sized arteries; it consists in the formation of lipid-rich plaques in the intima and inner media, whose pathophysiology is mostly driven by inflammation. Currently available interventio...

Gd-Mediated Spin-State Modulation of Co Sites Enhances Oxygen Electrocatalysis in Zn-Air Battery.

EP300 inhibition alleviates acute-on-chronic liver failure through modulation of scar-associated macrophages.

Exposure of Microglia to Interleukin-4 Represses NF-κB-Dependent Transcription of Toll-Like Receptor-Induced Cytokines

Interleukin (IL)-4 is a cytokine that affects both adaptive and innate immune responses. In the central nervous system, microglia express IL-4 receptors and it has been described that IL-4-exposed microglia acquire anti-inflammatory propert...

Ovarian cancer treatment and natural killer cell-based immunotherapy

BackgroundOvarian cancer (OC) is one of the malignant tumors that poses a serious threat to women’s health. Natural killer (NK) cells are an integral part of the immune system and have the ability to kill tumor cells directly or participate...

The Role of Cardiovascular Function in Endogenous Pain Modulation.

Microenvironment‐adaptive nanodecoy synergizes bacterial eradication, inflammation alleviation, and immunomodulation in promoting biofilm‐associated diabetic chronic wound healing cascade

Abstract The presence of bacterial biofilms and the occurrence of excessive inflammatory response greatly imped the healing process of chronic wounds in diabetic patients. However, effective strategies to simultaneously address these issues...

Advanced DFE, MLD, and RDE Equalization Techniques for Enhanced 5G mm-Wave A-RoF Performance at 60 GHz

This article presents the decision feedback equalizer (DFE), the maximum likelihood detection (MLD), and the radius-directed equalization (RDE) algorithms designed in MATLAB-R2018a to equalize the received signal in a dispersive optical lin...

Flexoelectricity Modulated Electron Transport of 2D Indium Oxide

Abstract The phenomenon of flexoelectricity, wherein mechanical deformation induces alterations in the electron configuration of metal oxides, has emerged as a promising avenue for regulating electron transport. Leveraging this mechanism, s...

Zonula occludens-1 at the ischemic blood–brain barrier: mechanisms of disruption, functional significance, and experimental modulation.

Diminished Auditory Responses during NREM Sleep Correlate with the Hierarchy of Language Processing.

Natural sleep provides a powerful model system for studying the neuronal correlates of awareness and state changes in the human brain. To quantitatively map the nature of sleep-induced modulations in sensory responses we presented participa...

Ultrasound neural interface enabling acute spinal cord monitoring and blood flow modulation.

Study of Efficiency Fractal Optical Modulator for insulator material by testing modulation transfer function

Chopper is an important component in optical system. It represents a device, which changes the angle between the coordinate and vision lines of the target for the electrical signal. The chopper modulates the optical signal by a frequency de...

HDAC3 inhibition alleviates neuroinflammation and white matter injury after subarachnoid hemorrhage through modulation of BDNF/TrkB/NF-κB signaling.

Computational Hyperspectral Camera Design Based on Co-Modulation of Diffractive Optical Element and Superposition Fabry-Perot Filter Array

Encoded computational hyperspectral cameras, propelled by advances in compressed sensing theory, making both miniaturization and real-time hyperspectral imaging feasible. Spectral-encoded or spatial-encoded hyperspectral imaging strategy ha...

A Reinforcement Learning based Adaptive and Efficient RWA in All Optical Networks

【Objective】Recent research efforts on Routing and Wavelength Assignment (RWA) for all optical networks are focused on Deep Reinforcement Learning (DRL) based algorithms. The DRL based RWA algorithms are mostly rely on the K Shortest Paths (...

Epigenetic dysregulation of high-grade gliomas: from heterogeneity to brain network modulation.

Machine learning in pain research

1. Introduction Pain and pain chronification are incompletely understood and unresolved medical problems that continue to have a high prevalence.14 It has been accepted that pain is a complex phenomenon.2,32,72 Contemporary methods of compu...