Reset
Showing 20 of 172 academic articles

The Utilization of Plant-Material-Loaded Vesicular Drug Delivery Systems in the Management of Pulmonary Diseases

Bongani Sannyboy Lukhele, Kokoette Bassey, Bwalya Angel Witika • Current Issues in Molecular Biology (2023)

Medicinal plants have been utilized to treat a variety of conditions on account of the bioactive properties that they contain. Most bioactive constituents from plants are of limited effectiveness, due to poor solubility, limited permeabilit...

DOAJ Open Access (DOAJ) DOI: 10.3390/cimb45120624

Exercise Training and Circulating Small Extracellular Vesicles: Appraisal of Methodological Approaches and Current Knowledge

Ian A. J. Darragh, Lorraine O’Driscoll, Lorraine O’Driscoll, Lorraine O’Driscoll et al. • Frontiers in Physiology (2021)

In response to acute exercise, an array of metabolites, nucleic acids, and proteins are enriched in circulation. Collectively termed “exercise factors,” these molecules represent a topical area of research given their speculated contributio...

DOAJ Open Access (DOAJ) DOI: 10.3389/fphys.2021.738333

Caracterização dos medicamentos descartados no ponto de coleta em uma universidade do nordeste brasileiro

Sharon Paoli Bias Ramos, Gabriel Rodrigues Martins de Freitas, Silvana Teresa Lacerda Jales • Jornal de Assistência Farmacêutica e Farmacoeconomia (2025)

Objetivo: analisar o perfil pós-consumo dos medicamentos descartados pela comunidade universitária no coletor disponibilizado no Centro de Ciências da Saúde da Universidade Federal da Paraíba. Métodos: O projeto de extensão Descarta CIM ins...

DOAJ Open Access (DOAJ) DOI: 10.22563/2525-7323.2025.v10.e00255

Vitamin E does not prevent Western diet-induced NASH progression and increases metabolic flux dysregulation in mice

Clinton M. Hasenour, Arion J. Kennedy, Tomasz Bednarski, Irina A. Trenary et al. • Journal of Lipid Research (2020)

Fatty liver involves ectopic lipid accumulation and dysregulated hepatic oxidative metabolism, which can progress to a state of elevated inflammation and fibrosis referred to as nonalcoholic steatohepatitis (NASH). The factors that control ...

DOAJ Open Access (DOAJ) DOI: 10.1194/jlr.RA119000183

Comparative effects of organic and inorganic fertilizers on photosynthetic pigments, oxidative metabolism, and yield in cotton (Gossypium hirsutum L.) under semi-arid field conditions

Cevher İlhan Cevheri, Nimet Kilinçoğlu, Vedat Beyyavas, Erdal Sakin et al. • BMC Plant Biology (2026)

Abstract This study was conducted under field conditions at Harran University’s Osmanbey Campus. Experimental plots were established using a randomized block design. Parameters such as chlorophyll a and b, carotenoids, total soluble protein...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12870-026-09295-y

Integrated Analysis of Liver Transcriptome, miRNA, and Proteome of Chinese Indigenous Breed Ningxiang Pig in Three Developmental Stages Uncovers Significant miRNA–mRNA–Protein Networks in Lipid Metabolism

Biao Li, Jinzeng Yang, Yan Gong, Yu Xiao et al. • Frontiers in Genetics (2021)

Liver is an important metabolic organ of mammals. During each transitional period of life, liver metabolism is programmed by a complex molecular regulatory system for multiple physiological functions, many pathways of which are regulated by...

DOAJ Open Access (DOAJ) DOI: 10.3389/fgene.2021.709521

Potassium mobilization and plant growth promotion by soil bacteria isolated from different agroclimatic zones of Odisha, India

Aiswarya PANDA, Ankita DASH, Bibhuti Bhusan MISHRA • Acta Agriculturae Slovenica (2021)

Potassium is essential for plant metabolism; improves immunity to stress and increase crop productivity. Soil contains insoluble form of potassium, which is unavailable for plant absorption. Potash mobilizing bacteria (KMB) solubilise compl...

DOAJ Open Access (DOAJ) DOI: 10.14720/aas.2021.117.3.1794

Metabolic modeling-based drug repurposing in Glioblastoma

Claudio Tomi-Andrino, Alina Pandele, Klaus Winzer, John King et al. • Scientific Reports (2022)

Abstract The manifestation of intra- and inter-tumor heterogeneity hinders the development of ubiquitous cancer treatments, thus requiring a tailored therapy for each cancer type. Specifically, the reprogramming of cellular metabolism has b...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-022-14721-w

Adipocyte Hyperplasia Facilitated Adipose Tissue Expansion to Alleviate Hepatopancreas Injury in Nile Tilapia (Oreochromis niloticus) Fed High-Fat Diet

Senyue Tan, Jiamin Wei, Ailan Diao, Douglas R. Tocher et al. • Aquaculture Nutrition (2025)

Previous studies showed that interplay between liver and adipose tissue was important for animals to adapt to high-fat diets (HFDs). While the mechanisms of adaptation to HFD are not fully understood in fish, we hypothesize that interaction...

DOAJ Open Access (DOAJ) DOI: 10.1155/anu/1260555

Transcriptomes Suggest That Pinniped and Cetacean Brains Have a High Capacity for Aerobic Metabolism While Reducing Energy-Intensive Processes Such as Synaptic Transmission

Cornelia Geßner, Alena Krüger, Lars P. Folkow, Wilfrid Fehrle et al. • Frontiers in Molecular Neuroscience (2022)

The mammalian brain is characterized by high energy expenditure and small energy reserves, making it dependent on continuous vascular oxygen and nutritional supply. The brain is therefore extremely vulnerable to hypoxia. While neurons of mo...

DOAJ Open Access (DOAJ) DOI: 10.3389/fnmol.2022.877349

Hacia una economía sostenible : dilemas del ecologismo actual

Joan Martínez Alier • Letras Verdes: Revista Latinoamericana de Estudios Socioambientales (2013)

Este texto fue leído en Barcelona el 14 de diciembre del 2010 al capítulo catalán del Club de Roma. Analiza las tendencias demográficas, la creciente producción de dióxido de carbono y la pérdida de biodiversidad en el mundo. Critica el opt...

DOAJ Open Access (DOAJ) DOI: 10.17141/letrasverdes.9.2011.900

Using Wearable Devices to Examine the Associations of Sedentary Behavior with Perceived and Performance Fatigability Among Older Adults: The Study of Muscle, Mobility and Aging (SOMMA)

Reagan E. Garcia, Anne B. Newman, Eileen Johnson, Yujia Susanna Qiao et al. • Sensors (2025)

Fatigability, a phenotype of poor energy regulation, is associated with lower physical activity in older adults, but independent associations with sedentary behavior are unknown. We examined whether sedentary behavior was associated with fa...

DOAJ Open Access (DOAJ) DOI: 10.3390/s25092722

<i>Sechium edule</i> var. <i>nigrum spinosum</i> (Chayote) Increases the mRNA Expression of Genes Encoding Sirtuins in Older Adults with Type 2 Diabetes Mellitus

Graciela Gavia-García, David Hernández-Álvarez, Taide Laurita Arista-Ugalde, Itzen Aguiñiga-Sánchez et al. • Molecules (2026)

Consumption of Sechium edule var. nigrum spinosum has antioxidant and hypoglycemic effects. Regarding the former, certain signaling pathways that influence these effects have already been proposed; however, the underlying molecular mechanis...

DOAJ Open Access (DOAJ) DOI: 10.3390/molecules31071182

Nature of Paleozoic Basement of the Catalan Coastal Ranges (Spain) and Tectonic Setting of the Priorat DOQ Wine Terroir: Evidence from Volcanic and Sedimentary Rocks

Pavel Kepezhinskas, Nikolai Berdnikov, Nikita Kepezhinskas, Natalia Konovalova et al. • Geosciences (2023)

The Paleozoic volcano-sedimentary rocks within the structural basement of the horst-and-graben system of the Catalan Coastal Ranges (CCR) are composed of black shale, volcaniclastic sediments, lava flows, sills and lithocrystalloclastic tuf...

DOAJ Open Access (DOAJ) DOI: 10.3390/geosciences13020031

Chromosome-level genome assembly and population genomics analysis of Camellia rubituberculata provide insights into adaptation to karst habitats

Chao Yan, Ming-tai An, Ming Tang, Xin-xiang Bai et al. • Plant Diversity (2026)

Karst flora confined to isolated ‘habitat islands’ evolve specialized adaptations and unique traits, serving as ideal models for investigating adaptive evolution and species diversification mechanisms. Camellia rubituberculata, endemic to t...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.pld.2025.09.004

Alterations in the gut microbiota and its metabolites contribute to metabolic maladaptation in dairy cows during the development of hyperketonemia

Zhengzhong Luo, Zhenlong Du, Yixin Huang, Tao Zhou et al. • mSystems (2024)

ABSTRACTMetabolic maladaptation in dairy cows after calving can lead to long-term elevation of ketones, such as β-hydroxybutyrate (BHB), representing the condition known as hyperketonemia, which greatly influences the health and production ...

DOAJ Open Access (DOAJ) DOI: 10.1128/msystems.00023-24

Methyl Jasmonate and Zinc Sulfate Induce Secondary Metabolism and Phenolic Acid Biosynthesis in Barley Seedlings

Xin Tian, Renjiao Zhang, Zhengfei Yang, Weiming Fang • Plants (2024)

This study aimed to reveal the impact of MeJA and ZnSO4 treatments on the physiological metabolism of barley seedlings and the content of phenolic acid. The results showed that MeJA (100 μM) and ZnSO4 (4 mM) treatments effectively increased...

DOAJ Open Access (DOAJ) DOI: 10.3390/plants13111512

ChsA, a Class Ⅱ Chitin Synthase, Contributes to Asexual Conidiation, Mycelial Morphology, Cell Wall Integrity, and the Production of Enzymes and Organic Acids in <i>Aspergillus niger</i>

Yunqi Zhu, Tong Liu, Yingsi Wang, Guojun Chen et al. • Journal of Fungi (2023)

Chitin synthases (CHSs) are vital enzymes for the synthesis of chitin and play important and differential roles in fungal development, cell wall integrity, environmental adaptation, virulence, and metabolism in fungi. However, except for Ch...

DOAJ Open Access (DOAJ) DOI: 10.3390/jof9080801

Exploring the Intestinal Microbiota and Metabolome Profiles Associated With Feed Efficiency in Pacific Abalone (Haliotis discus hannai)

Wenchao Yu, Wenchao Yu, Yisha Lu, Yisha Lu et al. • Frontiers in Microbiology (2022)

Feed efficiency (FE) is critical to the economic and environmental benefits of aquaculture. Both the intestines and intestinal microbiota play a key role in energy acquisition and influence FE. In the current research, intestinal microbiota...

DOAJ Open Access (DOAJ) DOI: 10.3389/fmicb.2022.852460