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Showing 20 of 398 academic articles

Progressive suppression of regulated cell death defines terminal macrophage states in liver cirrhosis

Kepu Zheng, Leiyang Dai, Yanghui Wen, Haitao Jiang et al. • Annals of Medicine (2026)

Background Macrophages are central regulators of liver immunity and fibrosis; Recent single-cell studies have characterized macrophage heterogeneity in cirrhosis; however, how regulated cell death programs shape their functional transitions...

DOAJ Open Access (DOAJ) DOI: 10.1080/07853890.2026.2690717

A Comparative Analysis of the Chloroplast Genomes of Four Polygonum Medicinal Plants

Shuai Guo, Shuai Guo, Xuejiao Liao, Xuejiao Liao et al. • Frontiers in Genetics (2022)

Polygonum is a generalized genus of the Polygonaceae family that includes various herbaceous plants. In order to provide aid in understanding the evolutionary and phylogenetic relationship in Polygonum at the chloroplast (cp) genome-scale l...

DOAJ Open Access (DOAJ) DOI: 10.3389/fgene.2022.764534

Effectiveness of Ultrasound Imaging in Assessing the Palpation Skills of Rotating Physicians

Peizhen Huang, Bin Zheng, Shan Liu, Lin Xu et al. • Frontiers in Genetics (2022)

As an important means of physical examination, palpation is usually limited to the physical examination before surgery and used as an auxiliary method for disease diagnosis in the field of surgery. In practice, palpation is also used in eve...

DOAJ Open Access (DOAJ) DOI: 10.3389/fgene.2022.894716

The Alberta Congenital Anomalies Surveillance System: a 40-year review with prevalence and trends for selected congenital anomalies, 1997–2019

R. Brian Lowry, Tanya Bedard, Xin Grevers, Susan Crawford et al. • Health Promotion and Chronic Disease Prevention in Canada (2023)

IntroductionCurrent published long-term provincial or territorial congenital anomaly data are lacking for Canada. We report on prevalence (per 1000 total births) and trends in 1997–2019, in Alberta, Canada, for selected congenital anomalies...

DOAJ Open Access (DOAJ) DOI: 10.24095/hpcdp.43.1.04

How can we promote gender and sex equality in orthopaedics and traumatology surgery? Research avenues perspectives

Agathe Yvinou, Romain Alain • Journal of Orthopaedic Surgery and Research (2025)

Abstract Gender and sex disparities persist in orthopaedic and traumatology surgery, making it one of the least diverse medical specialties worldwide. Despite growing women representation in medical education, women continue to be significa...

DOAJ Open Access (DOAJ) DOI: 10.1186/s13018-025-06170-8

Clinical Impact of Patient-Specific 3D Models in Neonatal Surgery: A Case-Based Review of Applications and Future Directions

Oscar Girón-Vallejo, Bernardo Garcia-Nuñez, Isidoro Narbona-Arias, Alexander Siles-Hinojosa et al. • Children (2025)

Three-dimensional (3D) modeling and printing technologies are increasingly used in pediatric surgery, offering improved anatomical visualization, surgical planning, and personalized approaches to complex conditions. Compared to standard ima...

DOAJ Open Access (DOAJ) DOI: 10.3390/children12091202

CAFs activated by YAP1 upregulate cancer matrix stiffness to mediate hepatocellular carcinoma progression

Wei Yan, Guo-hui Xiao, Li-juan Wang, Yan Zhou et al. • Journal of Translational Medicine (2025)

Abstract Background The stiffness of the matrix is closely related to the progression of hepatocellular carcinoma (HCC). Although direct targeting of stromal rigidity in HCC remains a clinical challenge, cancer-associated fibroblasts (CAFs)...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12967-025-06325-5

Patient-Reported Continued Benefits in Patients Treated with Pexidartinib for Tenosynovial Giant Cell Tumor Based on a Real-World Study in the United States

Margaret Wooddell PhD, MBA, Dong Dai PhD, Feng Lin PhD, Irene Pan MS et al. • Foot & Ankle Orthopaedics (2024)

Category: Other Introduction/Purpose: Tenosynovial giant cell tumors (TGCT) are neoplastic, inflammatory lesions that arise within the synovium and can be locally aggressive. Patients with TGCT frequently experience pain and joint swelling,...

DOAJ Open Access (DOAJ) DOI: 10.1177/2473011424S00422

Evaluation of Impedance and Reactance in the Intensive Treatment of Lymphoedema

Jose Maria Pereira De Godoy, Henrique Jose Pereira De Godoy, Maria De Fatima Guerreiro Godoy • Journal of Clinical and Diagnostic Research (2019)

Introduction: Lymphoedema is a progressive, chronic, clinical sign of an abnormal accumulation of macromolecules in the interstitial space that causes a buildup of fluids. Aim: To evaluate specific data of bioimpedance such as impedance and...

DOAJ Open Access (DOAJ) DOI: 10.7860/JCDR/2019/40158.12806

Fear of Falling After Total Knee Replacement: A Saudi Experience

Turki Aljuhani, Jayachandran Vetrayan, Mohammed A. Alfayez, Saleh A. Alshehri et al. • Clinics and Practice (2025)

Background: Fear of falling (FOF) is a significant concern among older adults, especially after total knee arthroplasty (TKA). FOF can limit daily activities, reduce quality of life, and hinder recovery. This study aimed to investigate the ...

DOAJ Open Access (DOAJ) DOI: 10.3390/clinpract15080146