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Combined Letrozole and Growth Hormone Therapy in Late-Pubertal Males with Advanced Bone Age and Open Knee Physes

Hui Zhang, Pengxiang Zhou, Yunpu Cui, Xuemei Wang et al. • Children (2026)

Background/Objectives: The therapeutic window for growth hormone (GH) therapy in late-pubertal males with advanced bone age (BA ≥ 15 years) is generally considered closed. Yet, open knee physes may indicate residual growth potential. This s...

DOAJ Open Access (DOAJ) DOI: 10.3390/children13081077

Polyoxometalates in Medicine

Jeffrey T. Rhule, Craig L. Hill, Deborah A. Judd, Raymond F. Schinazi • Chemical Reviews (1998)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPolyoxometalates in MedicineJeffrey T. Rhule, Craig L. Hill, Deborah A. Judd, and Raymond F. SchinaziView Author Information Department of Chemistry, Emory University, Atlanta, Georgia 30322 Veter...

OPENALEX DOI: https://doi.org/10.1021/cr960396q

Toll-like receptor 2 coordinates induction of IL-22 in lung macrophages following organic dust-induced inflammation

Emmanuel O. Oyewole, Emmanuel O. Oyewole, Emmanuel O. Oyewole, Pinaki Mondal et al. • Frontiers in Physiology (2026)

IntroductionOrganic dust exposures, particularly in occupational settings, induce airway inflammation and contribute to the development and progression of chronic lung disease and impaired tissue regeneration. Interleukin-22 (IL-22) is a pl...

DOAJ Open Access (DOAJ) DOI: 10.3389/fphys.2026.1880821

Underweight, body image, and weight loss measures among adolescents in Saudi Arabia: is it a fad or is there more going on?

Talal M. Hijji, Hassan Saleheen, Fadia S. AlBuhairan • International Journal of Pediatrics & Adolescent Medicine (2021)

Background and Objective: Adolescence is considered to be a pivotal point in which optimum nutrition and eating habits are developed. Although tackling the obesity epidemic has been much discussed, addressing the issue of underweight and bo...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.ijpam.2020.01.002

Receptor allostery promotes context-specific Sonic Hedgehog signaling during embryonic development

Miriam E. Dillard, Christina A. Daly, Rojalin Pradhan, Shariq S. Ansari et al. • Nature Communications (2026)

Abstract Sonic Hedgehog (SHH) signaling functions in temporal- and context-dependent manners to pattern diverse tissues during embryogenesis. The signal transducer Smoothened (SMO) is induced by sterols, oxysterols, and arachidonic acid (AA...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41467-026-75918-5

Current Trends in Tolerance Induction in Cow's Milk Allergy: From Passive to Proactive Strategies

Cansin Sackesen, Derya Ufuk Altintas, Aysen Bingol, Gulbin Bingol et al. • Frontiers in Pediatrics (2019)

This review addresses the current strategies of inducing tolerance development in infant and childhood cow's milk protein allergy (CMPA). The change in prevention strategies for CMPA has been emphasized based on the lack of evidence to supp...

DOAJ Open Access (DOAJ) DOI: 10.3389/fped.2019.00372

AI-generated draft replies to patient messages: exploring effects of implementation

Charlotte M. H. H. T. Bootsma-Robroeks, Charlotte M. H. H. T. Bootsma-Robroeks, Jessica D. Workum, Jessica D. Workum et al. • Frontiers in Digital Health (2025)

IntroductionThe integration of Large Language Models (LLMs) in Electronic Health Records (EHRs) has the potential to reduce administrative burden. Validating these tools in real-world clinical settings is essential for responsible implement...

DOAJ Open Access (DOAJ) DOI: 10.3389/fdgth.2025.1588143

AI and Chatbot-Supported Interventions for Physical Activity and Obesity-Related Lifestyle Behaviors: Scoping Review With Attention to Family Involvement

Qianxia Jiang, Xiayu Summer Chen, Dev Patel, Keith Brazendale et al. • JMIR Pediatrics and Parenting (2026)

Abstract BackgroundAI-enabled chatbots and related conversational systems can facilitate human–computer interaction through natural language, personalization, and automated support. In pediatric health promotion, these tools hav...

DOAJ Open Access (DOAJ) DOI: 10.2196/98889

Image-based quantification of histological features as a function of spatial location using the Tissue Positioning SystemResearch in context

Ruichen Rong, Yonglong Wei, Lin Li, Tao Wang et al. • EBioMedicine (2023)

Summary: Background: Tissues such as the liver lobule, kidney nephron, and intestinal gland exhibit intricate patterns of zonated gene expression corresponding to distinct cell types and functions. To quantitatively understand zonation, it...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.ebiom.2023.104698