Academic Articles & Research Papers

A Benzimidazole-Based N-Heterocyclic Carbene Derivative Exhibits Potent Antiproliferative and Apoptotic Effects against Colorectal Cancer

Background and Objectives: Colorectal cancer (CRC) remains a major global health issue. Although chemotherapy is the first-line treatment, its effectiveness is limited due to drug resistance developed in CRC. To overcome resistance and impr...

Effects on Dopaminergic Neurons Are Secondary in COX-Deficient Locomotor Dysfunction in Drosophila

Summary: Dopaminergic (DA) neurons have been implicated as key targets in neurological disorders, notably those involving locomotor impairment, and are considered to be highly vulnerable to mitochondrial dysfunction, a common feature of suc...

Genome-wide association analysis uncovers rice blast resistance alleles of Ptr and Pia

Abstract A critical step to maximize the usefulness of genome-wide association studies (GWAS) in plant breeding is the identification and validation of candidate genes underlying genetic associations. This is of particular importance in dis...

Preparation and evaluation of mushroom (Lentinus edodes) and mealworm (Tenebrio molitor) as dog food attractant

Chicken liver is a main protein source to prepare attractant for dog food. However, animal proteins are costly. Seeking high quality and low-cost protein sources has been a goal for the industry. Mushroom Lentinus edodes (L. edodes) and Mea...

MBPD: A multiple bacterial pathogen detection pipeline for One Health practices

Abstract Bacterial pathogens are one of the major threats to biosafety and environmental health, and advanced assessment is a prerequisite to combating bacterial pathogens. Currently, 16S rRNA gene sequencing is efficient in the open‐view d...

Publisher Correction: Endophenotype effect sizes support variant pathogenicity in monogenic disease susceptibility genes

Advances in microneedle-based drug delivery system for metabolic diseases: structural considerations, design strategies, and future perspectives

Abstract As the prevalence of metabolic diseases such as diabetes and obesity continue to rise, the search for more effective and convenient treatments has become a crucial issue in medical research. Microneedles (MNs), as an innovative dru...

Antibacterial and antioxidant effects of Punicalagin extracts from Punica granatum peels

The growing recognition of the health-promoting potential of compounds derived from natural sources, particularly those exhibiting antimicrobial and antioxidant activities, has resulted in a surge of research publications dedicated to explo...

Maternal dietary fiber intake during pregnancy and child development: the Japan Environment and Children's Study

BackgroundAnimal studies have shown that maternal low-fiber diets during pregnancy may impair brain development and function in offspring, but this has not been validated by epidemiological studies. The aim of this study was to investigate ...

Editorial: Institutional adaptation and transformation for climate resilience

Pakistan’s water resource management: Ensuring water security for sustainable development

Pakistan is blessed with abundant water resources but facing a critical water shortage due to a lack of storage facilities, poor water governance, and the adverse impacts of climate change. The burgeoning population at present 225 million, ...

Landscape patterns and their spatial associations with ecosystem service balance: Insights from a rapidly urbanizing coastal region of southeastern China

Abstract: Assessing ecosystem service (ES) balance and exploring critical drivers are crucial for landscape management. However, a lack of understanding of the determinants of the ecosystem service supply–demand budget, their spillover effe...

THE IMPACT OF ENVIRONMENTAL COST LEADERSHIP STRATEGY FOR ACHIEVING SUSTAINABLE DEVELOPMENT

The significance of environmental cost leadership strategies emerges as being an approach and a method for resolving the environment's problem within the Arabian aviation companies and how they affect the economics of air transportation in ...

Carbon neutralization frontier tracking

This systematic study on the international research trends in carbon neutrality underscores its critical role in combating global warming and advancing sustainable development. By leveraging the “Web of Science Core Collection” databases an...

A Sea Ice Entrapment Event in the Southern Chukchi Sea: Analysis and Prediction

Abstract Amplified Arctic warming is reducing sea ice cover, which is driving an increase in geopolitical interest in the region as it offers the possibility of reducing shipping times between Asia, Europe, and eastern North America, at the...

Geospatial for Good: Empowering Citizens for Sustainable Urban and Rural Futures

Geospatial technologies are rapidly emerging as pivotal tools for advancing sustainable urban and rural development through citizen empowerment in India and worldwide. This study systematically reviews peer-reviewed and grey literature to e...

Water conservation in arid and semi-arid basins exhibits a nonlinear effect on water quality improvement

Study region: The Weihe River Basin (WRB), a typical arid and semi-arid basin in China. Study focus: Water conservation regulates hydrological processes and pollutant transport, yet the response mechanisms of water quality to water conserva...

Housekeeping gene expression variability in differentiating and non-differentiating 3T3-L1 cells

ABSTRACTNormalization is a crucial step in gene expression analysis to avoid misinterpretation. Reverse transcription-quantitative polymerase chain reaction was used to measure the expression of 10 candidate housekeeping genes in non-differ...

Wastewater mining for circular potassium fertilisers: A critical scoping review of technologies, product formulations, and up-scaling challenges.

Photochemical Interactions of Nitrate Photolysis and Photosensitization of BBOA: Enhanced HONO Production and the Formation of Nitrophenols.