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Computational Tools; Indispensable Armamentarium of Medical Biotechnology

Nutan, Swapnil Jain, K Shilpa, Akanksha Tomar et al. • Indian Journal of Science and Technology (2016)

Objective: Computational infrastructure of medical biotechnology provides insight into elements of genomics, proteomics for understanding diseases and biological systems in a more comprehensive and systematic way. The present study exclusiv...

OPENALEX cc-by DOI: https://doi.org/10.17485/ijst/2016/v9i32/100745

Convergent Adaptation in the Dominant Global Hospital Clone ST239 of Methicillin-Resistant <named-content content-type="genus-species">Staphylococcus aureus</named-content>

Sarah L. Baines, Kathryn E. Holt, Mark B. Schultz, Torsten Seemann et al. • mBio (2015)

ABSTRACT Infections caused by highly successful clones of hospital-associated methicillin-resistant Staphylococcus aureus (HA-MRSA) are a major public health burden. The globally dominant sequence type 239 (ST239) HA-MRSA clone has persiste...

DOAJ Open Access (DOAJ) DOI: 10.1128/mBio.00080-15

Reimbursement Legislations and Decision Making for Orphan Drugs in Central and Eastern European Countries

Krzysztof Piotr Malinowski, Paweł Kawalec, Wojciech Trąbka, Marcin Czech et al. • Frontiers in Pharmacology (2019)

BackgroundReimbursement policies influence access of patients to orphan drugs in the European countries.ObjectivesTo provide a comprehensive description of orphan drug reimbursement policies and to assess reimbursement decision-making proce...

DOAJ Open Access (DOAJ) DOI: 10.3389/fphar.2019.00487

Investigating the genetic makeup of the major histocompatibility complex (MHC) in the United Arab Emirates population through next-generation sequencing

Nour al dain Marzouka, Halima Alnaqbi, Amira Al-Aamri, Guan Tay et al. • Scientific Reports (2024)

Abstract The Human leukocyte antigen (HLA) molecules are central to immune response and have associations with the phenotypes of various diseases and induced drug toxicity. Further, the role of HLA molecules in presenting antigens significa...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-024-53986-1

International Journal of Medical Biotechnology & Genetics

Saket RD, Kol S, Tripathi AK, Singh SP et al. • International Journal of Medical Biotechnology & Genetics (2022)

International Journal of Medical Biotechnology & Genetics (IJMBG) ISSN: 2379-1020 is a comprehensive, peer reviewed journal devoted to Medical Biotechnology and Genetics. publishes original research, latest developments, review papers, scie...

OPENALEX cc-by DOI: https://doi.org/10.19070/2379-1020

Unveiling the immunomodulatory dance: endothelial cells’ function and their role in non-small cell lung cancer

Sophia Daum, Lilith Decristoforo, Mira Mousa, Stefan Salcher et al. • Molecular Cancer (2025)

Abstract The dynamic interactions between tumor endothelial cells (TECs) and the immune microenvironment play a critical role in the progression of non-small cell lung cancer (NSCLC). In general, endothelial cells exhibit diverse immunomodu...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12943-024-02221-6

The M235T polymorphism in the angiotensinogen gene is not a major risk factor for diabetic nephropathy; a meta-analysis

Bhuneshwar Sahu, Shashikant Swarnakar, Henu Kumar Verma, Thavanati Parvathi Kumara Reddy et al. • Journal of Preventive Epidemiology (2022)

Introduction: Diabetic nephropathy (DN) is the leading cause of chronic kidney disease in diabetes patients. The angiotensin AGT M235T gene polymorphism, which is linked to the renin-angiotensin-aldosterone system (RAAS), has been extensive...

DOAJ Open Access (DOAJ) DOI: 10.34172/jpe.2022.15

A recent update on development, synthesis methods, properties and application of natural products derived carbon dots

Soumitra Sahana, Anupam Gautam, Rajveer Singh, Shivani Chandel • Natural Products and Bioprospecting (2023)

Abstract Natural resources are practically infinitely abundant in nature, which stimulates scientists to create new materials with inventive uses and minimal environmental impact. Due to the various benefits of natural carbon dots (NCDs) fr...

DOAJ Open Access (DOAJ) DOI: 10.1007/s13659-023-00415-x

Quantum Computing for Molecular Biology**

Alberto Baiardi, Matthias Christandl, Markus Reiher • ChemBioChem (2023)

Molecular biology and biochemistry interpret microscopic processes in the living world in terms of molecular structures and their interactions, which are quantum mechanical by their very nature. Whereas the theoretical foundations of these ...

OPENALEX other-oa DOI: https://doi.org/10.1002/cbic.202300120

The prospects of quantum computing in computational molecular biology

Carlos Outeiral, Martin Strahm, Jiye Shi, Garrett M. Morris et al. • Wiley Interdisciplinary Reviews Computational Molecular Science (2020)

Abstract Quantum computers can in principle solve certain problems exponentially more quickly than their classical counterparts. We have not yet reached the advent of useful quantum computation, but when we do, it will affect nearly all sci...

OPENALEX cc-by DOI: https://doi.org/10.1002/wcms.1481

A neural network approach to ordinal regression

Jianlin Cheng, Zheng Wang, Gianluca Pollastri • International Joint Conference on Neural Networks (IJCNN) (2008)

Ordinal regression is an important type of learning, which has properties of both classification and regression. Here we describe an effective approach to adapt a traditional neural network to learn ordinal categories. Our approach is a gen...

OPENALEX Open Access DOI: https://doi.org/10.1109/ijcnn.2008.4633963

Neural Networks and Computing

Tommy W. S. Chow, Siu‐Yeung Cho • Series in electrical and computer engineering (2007)

This book covers neural networks with special emphasis on advanced learning methodologies and applications. It includes practical issues of weight initializations, stalling of learning, and escape from a local minima, which have not been co...

OPENALEX DOI: https://doi.org/10.1142/p487

Graphs in molecular biology

Wolfgang K. Huber, Vincent J. Carey, Long Li, Seth Falcon et al. • BMC Bioinformatics (2007)

Graph theoretical concepts are useful for the description and analysis of interactions and relationships in biological systems. We give a brief introduction into some of the concepts and their areas of application in molecular biology. We d...

OPENALEX cc-by DOI: https://doi.org/10.1186/1471-2105-8-s6-s8 PMC: 1995545

Synthetic biology open language (SBOL) version 3.1.0

Buecherl Lukas, Mitchell Thomas, Scott-Brown James, Vaidyanathan Prashant et al. • Journal of Integrative Bioinformatics (2023)

Synthetic biology builds upon genetics, molecular biology, and metabolic engineering by applying engineering principles to the design of biological systems. When designing a synthetic system, synthetic biologists need to exchange informatio...

DOAJ Open Access (DOAJ) DOI: 10.1515/jib-2022-0058