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Showing 20 of 2,610 academic articles

Development and usability of VRainSUD’s cognitive training virtual reality platform for substance use disorders

Tânia Caetano, Maria Salomé Pinho, Hugo Freire, Dany Mota et al. • Scientific Reports (2025)

Abstract Cognitive deficits have been shown to increase the likelihood of relapse in individuals with substance use disorders (SUD). As such, cognitive training programs are important interventions for this population. In this study, we des...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-025-00922-6

Time dynamics of symptom progression in patients with acute pancreatitis: a Dynamic Time Warping analysis

Rui Han, Xiaoyu Deng, Hebing Liu, Yujie Duan et al. • Frontiers in Medicine (2025)

BackgroundAcute pancreatitis (AP) morbidity has been increasing in recent years. Patients with AP exhibit highly variable symptom patterns over time, posting challenges to traditional analytical methods. Dynamic Time Warping (DTW) effective...

DOAJ Open Access (DOAJ) DOI: 10.3389/fmed.2025.1703268

Depressive phenotype shapes behavioral, neuroendocrine and molecular responses to repetitive transcranial magnetic stimulation in preclinical models of depression

Marta Boffa, Marta Boffa, Sara Spalletti, Sara Spalletti et al. • Frontiers in Molecular Neuroscience (2026)

IntroductionRepetitive transcranial magnetic stimulation (rTMS) is an established non-invasive treatment for treatment-resistant depression (TRD), yet its neurobiological mechanisms remain only partially understood. We investigated whether ...

DOAJ Open Access (DOAJ) DOI: 10.3389/fnmol.2026.1939025

Inequities in Health Care Services Caused by the Adoption of Digital Health Technologies: Scoping Review

Rui Yao, Wenli Zhang, Richard David Evans, Guang Cao et al. • Journal of Medical Internet Research (2022)

BACKGROUND: Digital health technologies (ie, the integration of digital technology and health information) aim to increase the efficiency of health care delivery; they are rapidly adapting to health care contexts to provide improved medical...

OPENALEX cc-by DOI: https://doi.org/10.2196/34144 PMC: 8981004

Semi-rational design and modification of phosphoketolase to improve the yield of tyrosol in Saccharomyces cerevisiae

Na Song, Huili Xia, Yaoru Xie, Shuaikang Guo et al. • Synthetic and Systems Biotechnology (2025)

Tyrosol is an important component of pharmaceuticals, nutraceuticals, and cosmetics, and their biosynthetic pathways are currently a hot research topic. d-Erythrose 4-phosphate is a key precursor for the biosynthesis of tyrosol in Saccharom...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.synbio.2024.11.007

Older people and local public transit: Mobility effects of accessibility improvements in Sweden

Anders Wretstrand, Helena Svensson, Sofi Fristedt, Torbjörn Falkmer • Journal of Transport and Land Use (2009)

Several transportation factors concerning older and disabled people are under transition in Sweden at present. By the year 2010, the public transit system must be fully accessible for all passengers. The present survey studied older people,...

DOAJ Open Access (DOAJ) DOI: 10.5198/jtlu.v2i2.87

Development of an evaluation framework for health information communication technology in contemporary pharmacy practice

Ayomide Ogundipe, Tin Fei Sim, Lynne Emmerton • Exploratory Research in Clinical and Social Pharmacy (2023)

Background: Health information communication technology (ICT) has rapidly evolved in contemporary pharmacy practice worldwide. The Australian healthcare system is experiencing a paradigm shift to real-time interconnectivity for practitioner...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.rcsop.2023.100252

Add-On Selective Estrogen Receptor Modulators for Methadone Maintenance Treatment

Chieh-Liang Huang, Chieh-Liang Huang, Yao-Chang Chiang, Wei-Chun Chang et al. • Frontiers in Endocrinology (2021)

Methadone maintenance treatment (MMT) remains the cornerstone for the management of opiate abuse. However, MMT can be associated with complex factors, including complications during the tolerance phase, the inability of some patients to mai...

DOAJ Open Access (DOAJ) DOI: 10.3389/fendo.2021.638884

Health technology, quality and safety in a learning health system

Elizabeth Marie Borycki, Andre William Kushniruk • Healthcare Management Forum (2022)

Health technology quality and safety is an important issue for health informatics (i.e. digital health) professionals. Health technologies have been used to (1) collect data that can be analyzed to improve the quality and safety of healthca...

OPENALEX cc-by-nc DOI: https://doi.org/10.1177/08404704221139383 PMC: 9975897

A Prospective, Randomized Trial Comparing Hydromorphone and Nalbuphine for Postcesarean Patient-Controlled Analgesia and Developing a Risk Prediction Model for Inadequate Analgesia

Zhang K, Sun J, Zhang C, Jiao B et al. • Drug Design, Development and Therapy (2025)

Kaiwen Zhang,1,* Jiaoli Sun,1,* Caixia Zhang,2 Bo Jiao,1 Wencui Zhang,1 Shangchen Yu,1 Xueqin Cao,1 Zhiqiang Zhou,1 Guanglei Zhang,1 Xianwei Zhang1 1Department of Anesthesiology and Pain Medicine,Hubei Key Laboratory of Geri...

DOAJ Open Access (DOAJ)

The Downregulation of eIF3a Contributes to Vemurafenib Resistance in Melanoma by Activating ERK via PPP2R1B

Shi-Long Jiang, Shi-Long Jiang, Zhi-Bin Wang, Zhi-Bin Wang et al. • Frontiers in Pharmacology (2021)

Vemurafenib, a BRAF V600E inhibitor, provides therapeutic benefits for patients with melanoma, but the frequent emergence of drug resistance remains a challenge. An understanding of the mechanisms underlying vemurafenib resistance may gener...

DOAJ Open Access (DOAJ) DOI: 10.3389/fphar.2021.720619

Robotic-assisted anatomic anterior cruciate ligament reconstruction: a comparative analysis of modified transtibial and anteromedial portal techniques in cadaveric knees

Ling Zhang, Jinpeng Lin, Xuan Zhao, Mingwei Liu et al. • Frontiers in Bioengineering and Biotechnology (2024)

Introduction: This study employed surgical robot to perform anatomic single-bundle reconstruction using the modified transtibial (TT) technique and anteromedial (AM) portal technique. The purpose was to directly compare tunnel and graft cha...

DOAJ Open Access (DOAJ) DOI: 10.3389/fbioe.2024.1360560

Molecular Informatics, Chemometrics, and Sensory Omics for Constructing an Umami Peptide Cluster Library Across the Entire Lager Beer Brewing Process

Yashuai Wu, Ruiyang Yin, Wenjing Tian, Wanqiu Zhao et al. • Foods (2026)

Umami taste in lager beer not only determined body fullness and the backbone of aftertaste, but also affected the controllability and interpretability of flavor expression across the entire brewing process. Based on stage-wise sampling, pep...

DOAJ Open Access (DOAJ) DOI: 10.3390/foods15040641

Formative qualitative research on the potential for digital solutions to address diabetes care gaps in Tanzania and Sri Lanka

Ishu Kataria, Kaushik Ramaiya, Omary Ubuguyu, Sumithra Krishnamurthy Reddiar et al. • BMJ Open (2024)

Objectives Diabetes care remains unavailable and unaffordable for many people. Adapting models of care to low-income and middle-income country contexts is a priority. Digital technology offers substantial potential yet must surmount health ...

DOAJ Open Access (DOAJ) DOI: 10.1136/bmjopen-2023-078845

Remote Consultations in England During COVID-19: Challenges in Data Quality, Linkage, and Research Validity

Liliana Hidalgo-Padilla, Massar Dabbous, Kristoffer Halvorsrud, Thomas Beaney et al. • Online Journal of Public Health Informatics (2025)

AbstractThe COVID-19 pandemic accelerated the adoption of remote consultations across health care, requiring rapid adjustments in service delivery. Consequently, there is an urgent need to understand the impact of remote consultations on he...

DOAJ Open Access (DOAJ) DOI: 10.2196/66672

TRANSFER LEARNING: INCEPTION-V3 BASED CUSTOM CLASSIFICATION APPROACH FOR FOOD IMAGES

Vishwanath C Burkapalli, Priyadarshini C Patil • ICTACT Journal on Image and Video Processing (2020)

Deep-learning approach has become more popular in the field of image processing. When it is concerned with health issues, there are lots of improvements in the applications of food image classification by deep learning methods. Transfer lea...

DOAJ Open Access (DOAJ) DOI: 10.21917/ijivp.2020.0321

Oh brother, where art tau? Amyloid, neurodegeneration, and cognitive decline without elevated tau

Lauren E. McCollum, Sandhitsu R. Das, Long Xie, Robin de Flores et al. • NeuroImage: Clinical (2021)

Mild cognitive impairment (MCI) can be an early manifestation of Alzheimer’s disease (AD) pathology, other pathologic entities [e.g., cerebrovascular disease, Lewy body disease, LATE (limbic-predominant age-related TDP-43 encephalopathy)], ...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.nicl.2021.102717