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Showing 20 of 2,610 academic articles

Health technology assessment for digital health Technologies in India: a framework for action

Denny John, Abhirup Dutta Majumdar, Rakesh N Pillai, Sajda Khatoon et al. • International Journal of Technology Assessment in Health Care (2024)

OBJECTIVES: The aim of this study is to understand the path for establishing digital health technologies-health technology assessment (DHT-HTA) in India. METHODS: A rapid review of HTA and DHT frameworks on PubMed (MEDLINE) and Google Schol...

OPENALEX cc-by DOI: https://doi.org/10.1017/s0266462324000345 PMC: 11703630

Development of WEFIT Screening Tool for Assessing Pre-exercise Fitness Level for Older Adults in Peninsular Malaysia

Divya Vanoh, Arimi Fitri Mat Ludin, Suzana Shahar, Shahrul Azman Mohd Noah et al. • Journal of Health Research (2022)

Background: Pre-exercise screening is important to identify the fitness level of older adults prior to performing exercise. This study aimed to develop a screening tool for identifying older adults with poor physical fitness prior to exerci...

DOAJ Open Access (DOAJ) DOI: 10.56808/2586-940x.1006

Healthy lifestyle attenuates the clonal hematopoiesis-associated coronary artery disease risk

Yuxin Yang, Xuxiang Shen, Keyong Huang, Hongwei Liu et al. • Fundamental Research (2026)

Lifestyle factors and clonal hematopoiesis of indeterminate potential (CHIP) both contribute to the risk of developing coronary artery disease (CAD), but whether a healthy lifestyle could attenuate CHIP-related CAD risk is unknown. A total ...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.fmre.2025.09.012

Developing a nomogram to predict recurrent intussusception after pneumatic reduction of primary intussusception in children

Jie Liu, Danping Zeng, Zhihui Jiang, Wenli Xiu et al. • BMC Surgery (2024)

Abstract Backgroud Intussusception is a common acute abdominal disease in children, often leading to acute ileus in infants and young children. Objective This study aimed to develop and validate a nomogram for predicting recurrent intussusc...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12893-024-02578-x

Investigating the role of human frontal eye field in the pupil light reflex modulation by saccade planning and working memory

Tzu-Yu Hsu, Tzu-Yu Hsu, Hsin-Yi Wang, Hsin-Yi Wang et al. • Frontiers in Human Neuroscience (2022)

The pupil constricts in response to an increase in global luminance level, commonly referred to as the pupil light reflex. Recent research has shown that these reflex responses are modulated by high-level cognition. There is larger pupil co...

DOAJ Open Access (DOAJ) DOI: 10.3389/fnhum.2022.1044893

HEALTH TECHNOLOGY ASSESSMENT IN GERMANY

Matthias Perleth, Reinhard Busse • International Journal of Technology Assessment in Health Care (2000)

The objectives of this paper are to describe the status and development of health technology regulation with regard to coverage decisions and utilization, and to analyze the current situation of health technology assessment (HTA) in Germany...

OPENALEX DOI: https://doi.org/10.1017/s0266462300101072

Digital biomarkers: Convergence of digital health technologies and biomarkers

Srikanth Vasudevan, Anindita Saha, Michelle E. Tarver, Bakul Patel • npj Digital Medicine (2022)

Over the last decade, increasing digitization across the healthcare continuum has revolutionized medical research, diagnostics, and therapeutics. This digitization has led to rapid advancements in the development and adoption of digital hea...

OPENALEX cc-by DOI: https://doi.org/10.1038/s41746-022-00583-z PMC: 8956713

Health technology assessment in Finland

Marjukka Mākelä, Risto Paavo Roine • International Journal of Technology Assessment in Health Care (2009)

Since the 1990s, health policy makers in Finland have been supportive of evidence-based medicine and approaches to implement its results. The Finnish Office for Health Technology Assessment (Finohta) has grown from a small start in 1995 to ...

OPENALEX Open Access DOI: https://doi.org/10.1017/s0266462309090497

Pathway analysis of the impact of family function and self-efficacy on depression and anxiety in patients undergoing in vitro fertilization-embryo transfer

Fangliang Zou, Yi Fang, Yanshan Lin, Zikai Feng et al. • BMC Psychology (2024)

Abstract Background Patients undergoing assisted reproductive technology (ART) experience significant psychological distress due to infertility, with depression and anxiety being the most common manifestations. This study investigates the i...

DOAJ Open Access (DOAJ) DOI: 10.1186/s40359-024-02246-y

A 1-minute blood test detects decreased immune function and increased clinical risk in COVID-19 patients

Chirajyoti Deb, Allan N. Salinas, Tianyu Zheng, Aurea Middleton et al. • Scientific Reports (2021)

Abstract Upon infection with SARS-CoV-2, the virus that causes COVID-19, most people will develop no or mild symptoms. However, a small percentage of the population will become severely ill, and some will succumb to death. The clinical seve...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-021-02863-2

Predictive Value of Serum Cytokeratin 19 Level for the Feasibility of Conserving Ovaries in Endometrial Cancer

Jie Xu, Jie Xu, Can Chen, Can Chen et al. • Frontiers in Medicine (2021)

Objective: To determine the predictive value of cytokeratin 19 (CK19) for evaluating the safety of ovarian preservation in patients with endometrial cancer (EC).Methods: Five hundred and seventeen EC patients hospitalized from November 2010...

DOAJ Open Access (DOAJ) DOI: 10.3389/fmed.2021.670109

Melanopsin and Cone Photoreceptor Inputs to the Afferent Pupil Light Response

Andrew J. Zele, Andrew J. Zele, Prakash Adhikari, Prakash Adhikari et al. • Frontiers in Neurology (2019)

Background: Retinal photoreceptors provide the main stage in the mammalian eye for regulating the retinal illumination through changes in pupil diameter, with a small population of melanopsin-expressing intrinsically photosensitive retinal ...

DOAJ Open Access (DOAJ) DOI: 10.3389/fneur.2019.00529

Semaphorin 3A causes immune suppression by inducing cytoskeletal paralysis in tumour-specific CD8+ T cells

Mike B. Barnkob, Yale S. Michaels, Violaine André, Philip S. Macklin et al. • Nature Communications (2024)

Abstract Semaphorin-3A (SEMA3A) functions as a chemorepulsive signal during development and can affect T cells by altering their filamentous actin (F-actin) cytoskeleton. The exact extent of these effects on tumour-specific T cells are not ...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41467-024-47424-z

Operating pesticide use reduction within the boundary of food security in peri-urban settings

Yuquan W. Zhang, Bruce A. McCarl, Zhengwei Cao, Qiang Li et al. • Fundamental Research (2022)

Pesticide use in peri-urban areas affects the urban environment and public health, and reducing the use may present food security issues for urban dwellers. In this study, we explore how a municipality-adopted goal of a 20% reduction in pes...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.fmre.2022.04.003

Mangifera Indica leaf extracts promote hair growth via activation of Wnt signaling pathway in human dermal papilla cells

Haesoo Jung, Da-Min Jung, Sang-Soo Lee, Eun-Mi Kim et al. • Animal Cells and Systems (2022)

The crosstalk between androgens and Wnt signaling pathways is critical in the hair growth cycle. Therefore, natural products that target these two pathways for the inhibition of hair loss are sought after. In this study, we investigated the...

DOAJ Open Access (DOAJ) DOI: 10.1080/19768354.2022.2085790

Health technology in perspective

Tae‐Il Kim • Journal of Periodontal & Implant Science (2015)

The ongoing development of information and communication technology (ICT) is taking the healthcare industry to the next level. It allows an independent healthcare system by which anyone can easily obtain tne real-time measurement of individ...

OPENALEX cc-by-nc DOI: https://doi.org/10.5051/jpis.2015.45.1.1 PMC: 4341201

Are Key Principles for improved health technology assessment supported and used by health technology assessment organizations?

The International Working Group for HTA Advancement, Peter J. Neumann, Michael Drummond, Bengt Jönsson et al. • International Journal of Technology Assessment in Health Care (2010)

Previously, our group-the International Working Group for HTA Advancement-proposed a set of fifteen Key Principles that could be applied to health technology assessment (HTA) programs in different jurisdictions and across a range of organiz...

OPENALEX DOI: https://doi.org/10.1017/s0266462309990833

Serum amyloid beta 42 levels correlated with metabolic syndrome and its components

Kecheng Li, Kecheng Li, Xiaoli Zhou, Xiaoli Zhou et al. • Frontiers in Endocrinology (2024)

IntroductionBeta-amyloid accumulation in the brain appears to be a key initiating event in Alzheimer’s disease (AD), and factors associated with increased deposition of beta-amyloid are of great interest. Enhanced deposition of amyloid-β pe...

DOAJ Open Access (DOAJ) DOI: 10.3389/fendo.2024.1278477

Male Infertility and Its Correlates in Chuadanga District of Bangladesh

Sazin Islam, Md. Shariful Islam, Sharmin Akter, A. M. Mujahidul Islam et al. • American Journal of Men's Health (2025)

Male infertility is an escalating global health concern, yet it remains under-researched in Bangladesh. The factors contributing to this issue have not been thoroughly studied. This study aims to identify the factors associated with male in...

DOAJ Open Access (DOAJ) DOI: 10.1177/15579883251372452