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Piezo1 knockdown activates PI3K/AKT and enhances SPP1 to drive M2 macrophage polarization and reduce cardiac inflammation

Yunhan Zhang, Ying Zhang, Jiaoyan Song, Ziwen Zhao et al. • Scientific Reports (2026)

Abstract Piezo1 plays a key role in the immune response during sepsis. To date, our understanding of the role of Piezo1 in inflammatory diseases has mostly been limited to influencing vasomotor function and regulating inflammatory infiltrat...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-025-34794-7

Cofilin-1, LIMK1 and SSH1 are differentially expressed in locally advanced colorectal cancer and according to consensus molecular subtypes

Annie Cristhine Moraes Sousa-Squiavinato, Renata Ivo Vasconcelos, Adriana Sartorio Gehren, Priscila Valverde Fernandes et al. • Cancer Cell International (2021)

Abstract Background Colorectal cancer (CRC) is among the deadliest cancers, wherein early dissemination of tumor cells, and consequently, metastasis formation, are the main causes of mortality and poor prognosis. Cofilin-1 (CFL-1) and its m...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12935-021-01770-w

Linkage disequilibrium in wild mice.

Cathy C Laurie, Deborah A Nickerson, Amy D Anderson, Bruce S Weir et al. • PLoS Genetics (2007)

Crosses between laboratory strains of mice provide a powerful way of detecting quantitative trait loci for complex traits related to human disease. Hundreds of these loci have been detected, but only a small number of the underlying causati...

DOAJ Open Access (DOAJ) DOI: 10.1371/journal.pgen.0030144

Interacting roles of gut microbiota and T cells in the development of autoimmune hepatitis

Qingwei Wu, Zhifa Ge, Chengyu Lv, Qifeng He • Frontiers in Immunology (2025)

Autoimmune hepatitis (AIH) is a progressive liver inflammatory disease mediated by an autoimmune response, with an increasing incidence rate. In severe cases, AIH will rapidly progress to liver cirrhosis and liver failure and even lead to d...

DOAJ Open Access (DOAJ) DOI: 10.3389/fimmu.2025.1584001

Exploring innovation landscapes: a national cross-sectional study of Swedish primary care from the viewpoint of primary care managers

Sarah Samuelson, Eva-Lisa Petersson, Cecilia Björkelund, Marcus Praetorius Björk et al. • BMC Health Services Research (2026)

Abstract Background Innovation is increasingly necessary in primary care policy, and healthcare managers play a pivotal role in translating policy ambitions into practice and shaping organisational conditions that foster innovation. The aim...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12913-026-14870-y

Technology-Supported Behavior Change—Applying Design Thinking to mHealth Application Development

Ramona Schweitzer, Stephan Schlögl, Marco Schweitzer • European Journal of Investigation in Health, Psychology and Education (2024)

Non-communicable diseases are the leading cause of global deaths. The risk of their development and progression is increased by modifiable behavioral risk factors. Yet, despite the known benefits of primary and secondary prevention, people ...

DOAJ Open Access (DOAJ) DOI: 10.3390/ejihpe14030039

Embracing AI-Based Education: Perceived Social Presence of Human Teachers and Expectations About Machine Teachers in Online Education

Jihyun Kim, Kelly Merrill Jr, Kun Xu, Deanna D. Sellnow • Human-Machine Communication Journal (2022)

Technological advancements in education have turned the idea of machines as teachers into a reality. To better understand this phenomenon, the present study explores how college students develop expectations (or anticipations) about a machi...

DOAJ Open Access (DOAJ) DOI: 10.30658/hmc.4.9

Natural language processing with transformers: a review

Georgiana Țucudean, Marian Bucos, Bogdan Drăgulescu, Cătălin Daniel Căleanu • PeerJ Computer Science (2024)

Natural language processing (NLP) tasks can be addressed with several deep learning architectures, and many different approaches have proven to be efficient. This study aims to briefly summarize the use cases for NLP tasks along with the ma...

OPENALEX cc-by DOI: https://doi.org/10.7717/peerj-cs.2222 PMC: 11322986

Quantifying Gender Bias in Large Language Models Using Information-Theoretic and Statistical Analysis

Imran Mirza, Akbar Anbar Jafari, Cagri Ozcinar, Gholamreza Anbarjafari • Information (2025)

Large language models (LLMs) have revolutionized natural language processing across diverse domains, yet they also raise critical fairness and ethical concerns, particularly regarding gender bias. In this study, we conduct a systematic, mat...

DOAJ Open Access (DOAJ) DOI: 10.3390/info16050358

Natural Language Processing Techniques for Text Classification of Biomedical Documents: A Systematic Review

Cyrille YetuYetu Kesiku, Andrea Chaves-Villota, Begonya Garcia-Zapirain • Information (2022)

The classification of biomedical literature is engaged in a number of critical issues that physicians are expected to answer. In many cases, these issues are extremely difficult. This can be conducted for jobs such as diagnosis and treatmen...

DOAJ Open Access (DOAJ) DOI: 10.3390/info13100499

On Application of Natural Language Processing in Machine Translation

Zhaorong Zong, Changchun Hong • International Conference on Mechanical, Control and Computer Engineering (ICMCCE) (2018)

Natural language processing is the core of machine translation. In the history, its development process is almost the same as machine translation, and the two complement each other. This article compares the natural language processing of s...

OPENALEX DOI: https://doi.org/10.1109/icmcce.2018.00112

Sentiment Analysis and Topic Modeling of Indonesian Public Conversation about COVID-19 Epidemics on Twitter

Muhammad Habibi, Adri Priadana, Muhammad Rifqi Ma’arif • IJID (International Journal on Informatics for Development) (2021)

The World Health Organization (WHO) declared the COVID-19 outbreak has resulted in more than six million confirmed cases and more than 371,000 deaths globally on June 1, 2020. The incident sparked a flood of scientific research to help soci...

DOAJ Open Access (DOAJ) DOI: 10.14421/ijid.2021.2400