Academic Articles & Research Papers

Impact of preoperative insomnia on poor postoperative pain control after elective spine surgery and the modified Calgary postoperative pain after spine surgery (MCAPPS) score

Background: Approximately 30% to 64% of patients experience inadequate pain control following spine surgery. The Calgary postoperative pain after spine surgery (CAPPS) score was developed to identify this subset of patients. The impact of p...

Oxford Textbook of Public Health

SECTION 1: THE DEVELOPMENT OF THE DISCIPLINE OF PUBLIC HEALTH 1.1 The scope and concerns of public health 1.2 The history and development of public health in high-income countries 1.3 The history and development of public health in low- and...

Understanding Nigeria’s antibiotic resistance crisis among neonates and its future implications

Abstract A well-documented mounting public health crisis is the antibiotic crisis, which is most significantly felt in low-resource countries like Nigeria. This article sheds light on the rising level of antibiotic resistance in newborns in...

A History of Public Health

Since publication in 1958, George Rosen's classic book has been regarded as the essential international history of public health. Describing the development of public health in classical Greece, imperial Rome, England, Europe, the United St...

Dynamic alterations in stool microbiota composition following faecal transplantation in patients with inflammatory bowel disease.

Tailoring the active site for the oxygen evolution reaction on a Pt electrode

Electrocatalytic oxygen evolution is a key reaction for water splitting, but the detailed atomic structures of single-crystal electrodes under cycling conditions are still not fully understood. Here, the authors study the oxygen evolution a...

Spatiotemporal co-regulation of IL2 and TCR receptors reveals early antigen-driven synaptic synergy in human CD8(+) T cells.

From Isolation to Application: Utilising Phage‐Antibiotic Synergy in Murine Bacteremia Model to Combat Multidrug‐Resistant Enterococcus faecalis

ABSTRACT Enterococcus species, natural inhabitants of the human gut, have become major causes of life‐threatening bloodstream infections (BSIs) and the third most frequent cause of hospital‐acquired bacteremia. The rise of high‐level gentam...

Clinical characteristics of and risk factors for secondary bloodstream infection after pneumonia among patients infected with methicillin-resistant Staphylococcus aureus

Purpose: To investigate the clinical features and risk factors for methicillin-resistant Staphylococcus aureus (MRSA) pneumonia (MP) with secondary MRSA bloodstream infections (MRSA-BSI) (termed MP-BSI) compared with MP alone and to study t...

The LEGACy study: a European and Latin American consortium to identify risk factors and molecular phenotypes in gastric cancer to improve prevention strategies and personalized clinical decision making globally

Abstract Background Gastric Cancer (GC) is the fourth most deadly cancer worldwide. Enhanced understanding of its key epidemiological and molecular drivers is urgently needed to lower the incidence and improve outcomes. Furthermore, tumor b...

Pulsed Low-dose-rate Radiotherapy Remodels the Tumor Immune Microenvironment and is Associated With Crosstalk Between SPP1⁺ tumor-associated macrophages and GZMK⁺ CD8⁺ T cells.

DNA methylation patterns of circadian and ultradian genes are altered in the peripheral blood of patients with hidradenitis suppurativa

BackgroundHidradenitis suppurativa (HS) is a chronic inflammatory skin condition that affects hair follicles in areas with apocrine sweat glands, such as the underarms, groin, and buttocks. The pathogenesis of HS is not fully understood, bu...

Lung cancer tumor immune microenvironment: analyzing immune escape mechanisms and exploring emerging therapeutic targets

Lung cancer is the most common malignant tumor in the world. Presently, there are still problems, including a high recurrence rate, resistance, and serious toxic side effects, even if conventional treatments like chemotherapy, radiotherapy,...

Biological Potential of <i>Tsuga canadensis</i>: A Study on Seed, Cone Essential Oils, and Seed Lipophilic Extract

This study investigates the essential oil (EO) isolated from the seeds and cones of Canadian hemlock (Tsuga canadensis), highlighting notable differences in their chemical composition and biological activities. The seed EO was uniquely domi...

Basic and Clinical Immunology.

This text and review has been updated and revised since the last edition in 1974. The normal immunologic function and disease processes are presented clearly. New features include emphasis on normal immunologic function and disease processe...

Ultrahypofractionated radiotherapy better preserves B- and T-cell immunity than conventional fractionated radiotherapy in prostate cancer.

Dose-dependent spatiotemporal comparison of cell-assisted lipotransfer between stromal vascular fraction and adipose-derived stromal cells.

Characterization of Primate Antibody Responses to Administered Murine Monoclonal Immunoglobulin

Murine monoclonal antibodies (MAb) are currently being assessed for their utility as tools in cancer management. Anti-murine immunoglobulin responses have been observed in many patients receiving monoclonal antibody treatment. In this study...

Saccharomyces boulardii RC009 as an alternative to prophylactic antibiotics: effects on broiler chickens, performance, and gut microbiome

This study evaluates the effects of supplementing broiler chicken feed with the probiotic Saccharomyces cerevisiae var. boulardii RC009 as a sustainable alternative to prophylactic antibiotics. The focus was on productive performance, gut m...

Draft genome sequences of two hypermucoviscous carbapenem-resistant ST25 Klebsiella pneumoniae strains causing respiratory and systemic infections

ABSTRACT: Objectives: The emergence and spread of hypermucoviscous KPC-2-producing Klebsiella pneumoniae strains belonging to the sequence type 25 (ST25) clone was reported recently in Northwest Argentina as a leading cause of nosocomial in...