Academic Articles & Research Papers

A novel and accelerated method for integrated alignment and variant calling from short and long reads

BackgroundIntegrating short- and long-read sequencing technologies has become a promising approach for achieving accurate and comprehensive genomic analysis. Although short-read sequencing (Illumina, etc.) offers high base accuracy and cost...

Structural relationships within medical informatics

Medical informatics is the application of information science and information technology to the theoretical and practical problems of biomedical research, clinical practice, and medical education. Although it is broadly interdisciplinary, i...

A Focus on Simulation in Medical Informatics

This special issue of JAMIA addresses simulation, a methodology that holds great promise for the advancement of information technology in health care. Simulation has been termed a third domain, complementing both natural language and mathem...

The History and New Trends of Medical Informatics

ABSTRACT The breakthrough of the computer and information technologies in all the segments of the society, led to the needs for the computer and information technologies. The knowledge of information technology is now part of general litera...

Effects of individualized rTMS on functional connectivity related to the default mode network and frontal-parietal network in major depressive disorder: exploratory analysis of a randomized controlled trial

Objective: Repetitive transcranial magnetic stimulation (rTMS) has been shown to alleviate depressive and anxiety symptoms in patients with major depressive disorder (MDD), typically by targeting the dorsolateral (DLPFC) or dorsomedial pref...

Requirements for Vitiligo Registry Design in Iran: A Qualitative Content Analysis Study

Background: Vitiligo is a prevalent skin disorder that has significant biological and social consequences for the affected individuals. Therefore, appropriate measures should be taken to diagnose this disease and treat patients, and powerfu...

Data on biosynthesis of BPAF glucuronide, enzyme kinetics of BPAF glucuronidation, and molecular modeling

Bisphenol AF (BPAF) is in the body mainly metabolized to the corresponding bisphenol AF glucuronide (BPAF-G). While BPAF-G is not commercially available, enzyme-assisted synthesis of BPAF-G using the human recombinant enzyme UGT2A1, purific...

MBPD: A multiple bacterial pathogen detection pipeline for One Health practices

Abstract Bacterial pathogens are one of the major threats to biosafety and environmental health, and advanced assessment is a prerequisite to combating bacterial pathogens. Currently, 16S rRNA gene sequencing is efficient in the open‐view d...

The Questions of Medical Informatics

Each science is identified with the questions it raises with respect to its object of study. This paper discussed the formulation of the basic questions of medical informatics. From a historical point of view, it first dealt with the proble...

An updated database of human maximum skin fluxes and epidermal permeability coefficients for drugs, xenobiotics, and other solutes applied as aqueous solutions

The dataset represented in this article is referred to by the review article entitled “Topical drug delivery: history, percutaneous absorption, and product development” (MS Roberts et al., 2021) [1]. The dataset contains maximal flux (Jmax)...

Toward Home‐Based Telerehabilitation for Cerebral Palsy Patients: A Qualitative Study on Feasibility, Barriers and Facilitators

ABSTRACT Background and Aim Telerehabilitation has emerged as a promising solution to address accessibility, cost‐effectiveness, and continuity of care for patients requiring long‐term rehabilitation, like cerebral palsy (CP) patients. This...

Correction: Five-year dementia prediction and decision support system based on real-world data

Development and production of an oligonucleotide MuscleChip: use for validation of ambiguous ESTs

Abstract Background We describe the development, validation, and use of a highly redundant 120,000 oligonucleotide microarray (MuscleChip) containing 4,601 probe sets representing 1,150 known genes expressed in muscle and 2,075 EST clusters...

Data on farmers’ perception and acceptance of sustainability standards

The presented data informs about a comprehensive online survey on the perception and acceptance of farm sustainability standards amongst German farmers. We conducted the online interviews, with a total of 598 adequately answered questionnai...

HRI-confusion: A multimodal dataset for modelling and detecting user confusion in situated human-robot interaction

The dataset was collected from 28 participants (17 female, 9 male, and 1 non-binary) for a study aimed at modelling and detecting user social behaviours with different confusion states in task-oriented situated human-robot interaction (HRI)...

Data describing the poor outcome associated with a breast cancer diagnosis in the post-weaning period

Postpartum breast cancer (PPBC) - which according to new data, can extend to 5–10 years after the birth - are estimated to represent 35–55% of all cases of breast cancer in women younger than 45 years. Increasing clinical evidence indicates...

Contribution of EFMI to development of medical informatics. European Federation for Medical Informatics.

The European Federation for Medical Informatics has been established in 1976. At the MIE 96 it has celebrated the 20th anniversary of its existence. During these 20 years the number of number of national societies who became a member has be...

The Cornerstones of Medical Informatics

The changes in the health care system over the next decade are goint to make the last 20 years seem like good old days of relative stability. We will continue to see new drugs, new devices, and new techniques; however, the true megachanges ...

Effects of environmentally relevant ibuprofen and valproic acid exposure on zebrafish behavior

Active pharmaceutical ingredients (APIs) are increasingly entering aquatic environments due to human and veterinary use, wastewater discharges, and inadequate waste containment, raising significant concerns for both ecosystems and human hea...

Case-based medical informatics

BACKGROUND: The "applied" nature distinguishes applied sciences from theoretical sciences. To emphasize this distinction, we begin with a general, meta-level overview of the scientific endeavor. We introduce the knowledge spectrum and four ...