Reset
Showing 20 of 1,929 academic articles

Investigating the genetic makeup of the major histocompatibility complex (MHC) in the United Arab Emirates population through next-generation sequencing

Nour al dain Marzouka, Halima Alnaqbi, Amira Al-Aamri, Guan Tay et al. • Scientific Reports (2024)

Abstract The Human leukocyte antigen (HLA) molecules are central to immune response and have associations with the phenotypes of various diseases and induced drug toxicity. Further, the role of HLA molecules in presenting antigens significa...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-024-53986-1

Flexibility-powered Pickering emulsion enhances mucus permeability to alleviate ulcerative colitis

Jiali Lv, Chen Cheng, Xinran Liu, Jinhua Song et al. • Journal of Nanobiotechnology (2025)

Abstract The physicochemical properties of oral drug delivery carriers significantly influence their interactions with the intestinal barrier, which, in turn, affect their in vivo fate and therapeutic efficacy. As a delivery system with a h...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12951-025-03829-6

A Novel Prognostic Scoring Model for Myelodysplastic Syndrome Patients With SF3B1 Mutation

Liya Ma, Bin Liang, Huixian Hu, Wenli Yang et al. • Frontiers in Oncology (2022)

The outcomes of myelodysplastic syndrome (MDS) patients with SF3B1 mutation, despite identified as a favorable prognostic biomarker, are variable. To comprehend the heterogeneity in clinical characteristics and outcomes, we reviewed 140 MDS...

DOAJ Open Access (DOAJ) DOI: 10.3389/fonc.2022.905490

Dynamic monitoring of circulating tumor DNA reveals outcomes and genomic alterations in patients with relapsed or refractory large B-cell lymphoma undergoing CAR T-cell therapy

Wei Liu, Yan Xu, Yi Wang, Lugui Qiu et al. • Journal for ImmunoTherapy of Cancer (2024)

Background Over 50% of patients with relapsed or refractory large B-cell lymphoma (r/r LBCL) receiving CD19-targeted chimeric antigen receptor (CAR19) T-cell therapy fail to achieve durable remission. Early identification of relapse or prog...

DOAJ Open Access (DOAJ) DOI: 10.1136/jitc-2023-008450

PRODUCTION OF L-TRYPTOPHAN BY MUTANTS OF CORYNEBACTERIUM GLUTAMICUM

Hamies Mohamed, Ghada El Nady, A. Ali, A. Abdel-Razik et al. • Arab Universities Journal of Agricultural Sciences (2018)

L-Tryptophan, is one of the amino acids, also is one of the 9 essential amino acids of human which cannot be synthesized internally by him, microbial production is the main method for obtaining tryptophan for commercial uses. Typical microo...

DOAJ Open Access (DOAJ) DOI: 10.21608/ajs.2018.28383

Regulatory requirements for the registration of generic medicines and format of drug dossiers: procedures in Sri Lanka in comparison with selected regulatory authorities

D. Thambavita, P. Galappatthy, R. L. Jayakody • Journal of Pharmaceutical Policy and Practice (2018)

Background The regulatory requirements for approval of generic medicines and the format of compiling drug dossiers vary among regulatory authorities. The variation is particularly wide between High-income countries (HIC) and lower and middl...

DOAJ Open Access (DOAJ) DOI: 10.1186/s40545-018-0141-2

‘Incense is the one that keeps the air fresh’: indoor air quality perceptions and attitudes towards health risk

Ashley Williams, Kayla Schulte, Diana Varaden • BMC Public Health (2024)

Abstract Background Air pollution is of significant environmental and public health concern globally. While much research has historically focused on outdoor air pollution, indoor air pollution has been relatively under-explored despite its...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12889-024-20635-1

The impact of the student-supervisor relationship on graduate student mental health: An integrative review

Huma Khalid, Sandra Della Porta • Social Sciences and Humanities Open (2026)

In recent years, the mental health of graduate students has become a prominent concern in higher education, with many students experiencing elevated levels of stress, anxiety, depression, burnout, and psychological distress. These challenge...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.ssaho.2026.103794