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The Downregulation of eIF3a Contributes to Vemurafenib Resistance in Melanoma by Activating ERK via PPP2R1B

Shi-Long Jiang, Shi-Long Jiang, Zhi-Bin Wang, Zhi-Bin Wang et al. • Frontiers in Pharmacology (2021)

Vemurafenib, a BRAF V600E inhibitor, provides therapeutic benefits for patients with melanoma, but the frequent emergence of drug resistance remains a challenge. An understanding of the mechanisms underlying vemurafenib resistance may gener...

DOAJ Open Access (DOAJ) DOI: 10.3389/fphar.2021.720619

Designing mobile health technology for bipolar disorder

Jakob E. Bardram, Mads M. Frost, Károly Szántó, Maria Faurholt‐Jepsen et al. • CHI Conference on Human Factors in Computing Systems (2013)

An increasing number of pervasive healthcare systems are being designed, that allow people to monitor and get feedback on their health and wellness. To address the challenges of self-management of mental illnesses, we have developed the MON...

OPENALEX DOI: https://doi.org/10.1145/2470654.2481364

Health Technologies 'In the Wild'

Stefan Rennick‐Egglestone, Sarah E. Knowles, Gill R. Toms, Penny Bee et al. • CHI Conference on Human Factors in Computing Systems (2016)

The widespread deployment of technology by professional health services will provide a substantial opportunity for studies that consider usage in naturalistic settings. Our study has documented experiences of engaging with technologies inte...

OPENALEX Open Access DOI: https://doi.org/10.1145/2858036.2858128

Purification, Characterization and Bactericidal Action of Lysozyme, Isolated from <i>Bacillus subtillis</i> BSN314: A Disintegrating Effect of Lysozyme on Gram-Positive and Gram-Negative Bacteria

Muhammad Naveed, Yadong Wang, Xian Yin, Malik Wajid Hussain Chan et al. • Molecules (2023)

In the present study, lysozyme was purified by the following multi-step methodology: salt (ammonium sulfate) precipitation, dialysis, and ultrafiltration. The lysozyme potential was measured by enzymatic activity after each purification ste...

DOAJ Open Access (DOAJ) DOI: 10.3390/molecules28031058

Disrupted Functional Connectivity of Cornu Ammonis Subregions in Amnestic Mild Cognitive Impairment: A Longitudinal Resting-State fMRI Study

Hui Li, Hui Li, Xiuqin Jia, Xiuqin Jia et al. • Frontiers in Human Neuroscience (2018)

Background: The cornu ammonis (CA), as part of the hippocampal formation, represents a primary target region of neural degeneration in amnestic mild cognitive impairment (aMCI). Previous studies have revealed subtle structural deficits of t...

DOAJ Open Access (DOAJ) DOI: 10.3389/fnhum.2018.00413

Medical, dental, and nursing students’ attitudes and knowledge towards artificial intelligence: a systematic review and meta-analysis

Hamidreza Amiri, Samira Peiravi, Seyedeh sara rezazadeh shojaee, Motahareh Rouhparvarzamin et al. • BMC Medical Education (2024)

Abstract Background Nowadays, Artificial intelligence (AI) is one of the most popular topics that can be integrated into healthcare activities. Currently, AI is used in specialized fields such as radiology, pathology, and ophthalmology. Des...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12909-024-05406-1

The Comparability of Men Who Have Sex With Men Recruited From Venue-Time-Space Sampling and Facebook: A Cohort Study

Hernandez-Romieu, Alfonso C, Sullivan, Patrick S, Sanchez, Travis H, Kelley, Colleen F et al. • JMIR Research Protocols (2014)

BackgroundRecruiting valid samples of men who have sex with men (MSM) is a key component of the US human immunodeficiency virus (HIV) surveillance and of research studies seeking to improve HIV prevention for MSM. Social media, such as Face...

DOAJ Open Access (DOAJ) DOI: 10.2196/resprot.3342

Data for the co-expression and purification of human recombinant CaMKK2 in complex with calmodulin in Escherichia coli

Lisa Gerner, Steffi Munack, Koen Temmerman, Ann-Marie Lawrence-Dörner et al. • Data in Brief (2016)

Calcium/calmodulin-dependent kinase kinase 2 (CaMKK2) has been implicated in a range of conditions and pathologies from prostate to hepatic cancer. Here, we describe the expression in Escherichia coli and the purification protocol for the f...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.dib.2016.06.033

ACHENY: A standard Chenopodiaceae image dataset for deep learning models

Ahmad Heidary-Sharifabad, Mohsen Sardari Zarchi, Sima Emadi, Gholamreza Zarei • Data in Brief (2021)

This paper contains datasets related to the “Efficient Deep Learning Models for Categorizing Chenopodiaceae in the wild” (Heidary-Sharifabad et al., 2021). There are about 1500 species of Chenopodiaceae that are spread worldwide and often a...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.dib.2021.107478

Isolation, characterisation and antibiotic susceptibility of staphylococcal isolates with special reference to methicillin-resistant Staphylococcus aureus from the anterior nares of healthcare workers in A tertiary healthcare centre

Chaurasia Mukul, Agrawa Neha, Chourasia Ankita, Bhatnagar Monica et al. • Scripta Medica (2021)

Background: Staphylococcus aureus (S. aureus) and its resistant form methicillinresistant S. aureus (MRSA) is one of the most common nosocomial pathogens causing a wide range of infections in humans. The anterior nares are the main ecologic...

DOAJ Open Access (DOAJ) DOI: 10.5937/scriptamed52-31190

Evaluation of pragmatic oxygenation measurement as a proxy for Covid-19 severity

Maaike C. Swets, Steven Kerr, James Scott-Brown, Adam B. Brown et al. • Nature Communications (2023)

Abstract Choosing optimal outcome measures maximizes statistical power, accelerates discovery and improves reliability in early-phase trials. We devised and evaluated a modification to a pragmatic measure of oxygenation function, the $$S/F$...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41467-023-42205-6

Real-World Evaluation of AI-Driven Diabetic Retinopathy Screening in Public Health Settings: Validation and Implementation Study

Mona Duggal, Anshul Chauhan, Vishali Gupta, Ankita Kankaria et al. • JMIR Medical Informatics (2025)

Abstract BackgroundArtificial intelligence (AI) algorithms offer an effective solution to alleviate the burden of diabetic retinopathy (DR) screening in public health settings. However, there are challenges in translating diagno...

DOAJ Open Access (DOAJ) DOI: 10.2196/67529

Mapping Intellectual Structure of Health Literacy Area Based on Co-Word Analysis in Web of Science Database during the Years 1993-2017

Fatemeh Baji, Fereydoun Azadeh, Parastoo Parsaei-Mohammadi, Shoukat Parmah • مدیریت اطلاعات سلامت (2018)

Introduction: Creating an image of the conceptual structure of health literacy area, as well as the study of interdisciplinary and the relationship between its domains seems necessary. The present study examined the intellectual structure o...

DOAJ Open Access (DOAJ) DOI: 10.22122/him.v15i3.3577

Effects of chronic taurine administration on healthy pregnant rats and the consequences on the offspring: Datasets for motor tests and oxidative stress

Viridiana Vargas-Castro, Ricardo Gomez-Diaz, Victor M. Blanco-Alvarez, Constantino Tomas-Sanchez et al. • Data in Brief (2022)

We present the data for taurine (2-aminoethanesulfonic acid) treatment to healthy pregnant Sprague Dawley rats (SD). At embryonic day 15 (E15), healthy pregnant SD rats were given taurine treatment (50 mg/L drinking water) and then to their...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.dib.2022.108015

Penetration and familiarity of false belief on neuroscience among students and its modifiability

Takeshi Hatta, Taketoshi Hatta, Kazuhisa Todayama, Minoru Karasawa • Journal of Human Environmental Studies (2010)

In Study 1, the degrees of penetration and familiarity of false belief on neuroscience, especially brain imaging, among students were surveyed using a questionnaire technique. A total number of 485 students from medical school, school of nu...

DOAJ Open Access (DOAJ) DOI: 10.4189/shes.8.155

A genome-wide association study on meat consumption in a Japanese population: the Japan Multi-Institutional Collaborative Cohort study

Yasuyuki Nakamura, Akira Narita, Yoichi Sutoh, Nahomi Imaeda et al. • Journal of Nutritional Science (2021)

Recent genome-wide association studies (GWAS) on the dietary habits of the Japanese population have shown that an effect rs671 allele was inversely associated with fish consumption, whereas it was directly associated with coffee consumption...

DOAJ Open Access (DOAJ) DOI: 10.1017/jns.2021.49