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Effects of urea, metal ions and surfactants on the binding of baicalein with bovine serum albumin

Atanu Singha Roy, Amit Kumar Dinda, Nitin Kumar Pandey, Swagata Dasgupta • Journal of Pharmaceutical Analysis (2016)

The interaction of baicalein with bovine serum albumin (BSA) was investigated with the help of spectroscopic and molecular docking studies. The binding affinity of baicalein towards BSA was estimated to be in order of 105 M−1 from fluoresce...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.jpha.2016.04.001

Efficacy, safety, and quality of life 4 years after valoctocogene roxaparvovec gene transfer for severe hemophilia A in the phase 3 GENEr8-1 trial

Andrew D. Leavitt, Johnny Mahlangu, Priyanka Raheja, Emily Symington et al. • Research and Practice in Thrombosis and Haemostasis (2024)

Background: Valoctocogene roxaparvovec, an adeno-associated virus-mediated gene therapy for severe hemophilia A, enables endogenous factor (F)VIII expression and provides bleed protection. Objectives: Determine valoctocogene roxaparvovec du...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.rpth.2024.102615

Exercise Training and Circulating Small Extracellular Vesicles: Appraisal of Methodological Approaches and Current Knowledge

Ian A. J. Darragh, Lorraine O’Driscoll, Lorraine O’Driscoll, Lorraine O’Driscoll et al. • Frontiers in Physiology (2021)

In response to acute exercise, an array of metabolites, nucleic acids, and proteins are enriched in circulation. Collectively termed “exercise factors,” these molecules represent a topical area of research given their speculated contributio...

DOAJ Open Access (DOAJ) DOI: 10.3389/fphys.2021.738333

Prodigiosin as an Algicidal Agent: Inhibition of Pigment Accumulation and Photosynthetic Efficiency of Cyanobacteria Involved in Algal Blooms

Chaobo Zhang, Chengshuai Xu, Zhenxia Zhu, Xiu Zhang et al. • Microorganisms (2025)

Eutrophication facilitates the proliferation of cyanobacteria, ultimately leading to the formation of harmful cyanobacterial blooms. Prodigiosin, known for its algicidal properties, presents significant potential for application in water po...

DOAJ Open Access (DOAJ) DOI: 10.3390/microorganisms13112569

EFFECT OF VITAMIN A ON CYCLOSPORINE NEPHROTOXICITY IN UNINEPHRECTOMIZED RATS

Hoda Mohamed, Hazar Yacoub, Heba Ameen, Dureah Sebah • Zagazig Journal of Pharmaceutical Sciences (1997)

The influence of vitamin A (1.5 mg kg-1 body weight) administration for two weeks on cyclosporine A (CsA, 25 mg kg-1 body weight) induced renal dysfunction has been investigated in uninephrectomized and sham nephrectomized rats. Single kidn...

DOAJ Open Access (DOAJ) DOI: https://doi.org/10.21608/zjps.1997.184951

Molecular Dynamics and In Vitro Studies Elucidating the Tunable Features of Reconfigurable Nanodiscs for Guiding the Optimal Design of Curcumin Formulation

Yongxiao Li, Wanting Xu, Xinpei Wang, Ruizhi Lai et al. • Bioengineering (2024)

In this study, we advance our exploration of Apolipoprotein A-I (apoA-I) peptide analogs (APAs) for their application in nanodisc (ND) assembly, focusing on the dynamic conformational characteristics and the potential for drug delivery. We ...

DOAJ Open Access (DOAJ) DOI: 10.3390/bioengineering11030245

Perspective on the Therapeutics of Anti-Snake Venom

Isabel Gómez-Betancur, Vedanjali Gogineni, Andrea Salazar-Ospina, Francisco León • Molecules (2019)

Snakebite envenomation is a life-threatening disease that was recently re-included as a neglected tropical disease (NTD), affecting millions of people in tropical and subtropical areas of the world. Improvement in the therapeutic approaches...

DOAJ Open Access (DOAJ) DOI: 10.3390/molecules24183276

Enteric Coating Enhances the Biopharmaceutical Performance of a Silica–Lipid Formulation of Abiraterone Acetate

Ali Taheri, Ruba Almasri, Anthony Wignall, Felicia Feltrin et al. • Pharmaceutics (2025)

Background/Objectives: Lipid-based formulations are widely used to enhance the oral bioavailability of poorly water-soluble drugs. However, for weakly basic drugs with higher solubility under acidic conditions, precipitation and recrystalli...

DOAJ Open Access (DOAJ) DOI: 10.3390/pharmaceutics17101289

Comparison of Vitamin B1 (Thiamin hydrochloride) Level in Brown Rice (Oryza nivara S.D.Sharma & Shastry) and Cooked Brown Rice by Alkalimetry Methods

Emerita Dyah Ayu Purwita Sari, Hendra Budiman, Anita Agustina Styawan, Choiril Hana Mustofa • Journal of Food and Pharmaceutical Sciences (2025)

Brown rice (Oryza nivara S.D.Sharma & Shastry) is a rice variety that belongs to the Graminae family. Brown rice contains vitamins A, B, C, Zn and B complex. Vitamin B1 is one type of vitamin that is not stable. Its stability is influenced ...

DOAJ Open Access (DOAJ) DOI: 10.22146/jfps.17037

Modified Riceberry rice extract suppresses melanogenesis-associated cell differentiation through tyrosinase-mediated MITF downregulation on B16 cells and in vivo zebrafish embryos

Teerapat Rodboon, Sasithorn Sirilun, Seiji Okada, Ryusho Kariya et al. • Research in Pharmaceutical Sciences (2020)

Background and purpose: Excessive melanin production caused by overactive tyrosinase (TYR) enzyme results in several dermatological problems. The TYR inhibitor, derived from metabolite changes during fermentation, has been well recognized f...

DOAJ Open Access (DOAJ) DOI: 10.4103/1735-5362.297852

Palladium-Catalyzed Stereoselective Construction of 1,3-Stereocenters Displaying Axial and Central Chirality via Asymmetric Alkylations

Aiqi Xue, Xingfu Wei, Yue Huang, Jingping Qu et al. • Molecules (2023)

The concurrent construction of 1,3-stereocenters remains a challenge. Herein, we report the development of stereoselective union of a point chiral center with allenyl axial chirality in 1,3-position by Pd-catalyzed asymmetric allenylic alky...

DOAJ Open Access (DOAJ) DOI: 10.3390/molecules28072927

Surface-Modified Nanocellulose for Application in Biomedical Engineering and Nanomedicine: A Review

Tortorella S, Vetri Buratti V, Maturi M, Sambri L et al. • International Journal of Nanomedicine (2020)

Silvia Tortorella, Veronica Vetri Buratti, Mirko Maturi, Letizia Sambri, Mauro Comes Franchini, Erica Locatelli Department of Industrial Chemistry “Toso Montanari”, Alma Mater Studiorum – University of Bologna, Bologna 401...

DOAJ Open Access (DOAJ)

Characterization of low-nitrogen quantum diamond for pulsed magnetometry applications

Jiashen Tang, Jiashen Tang, Connor A. Roncaioli, Andrew M. Edmonds et al. • Frontiers in Quantum Science and Technology (2025)

Ensembles of nitrogen-vacancy (NV) centers in diamond are versatile quantum sensors with broad applications in the physical and life sciences. The concentration of neutral substitutional nitrogen ([Ns0]) strongly influences NV electronic sp...

DOAJ Open Access (DOAJ) DOI: 10.3389/frqst.2025.1701548

Developing an Interferogram-Based Module with Machine Learning for Maintaining Leveling of Glass Substrates

Syuan-Cheng Chang, Chung-Ping Chang, Yung-Cheng Wang, Chi-Chieh Chu • Machines (2023)

In this research, we propose a method that utilizes machine learning to maintain the parallelism of the resonant cavity in a Fabry–Perot interferometer designed specifically for glass substrates. Based on the optical principle and theory, w...

DOAJ Open Access (DOAJ) DOI: 10.3390/machines11060668

Controlled Plasmonic Coupling in Silver Nanoplate Dimers for Enhanced Plasmonic Sensing

Lucrezia Catanzaro, Marcello Condorelli, Mario Pulvirenti, Luisa D’urso et al. • Nanomaterials (2026)

Noble metal nanostructures provide versatile platforms for light manipulation through localized surface plasmon resonances (LSPRs). Among them, triangular silver nanoplates (AgNPTs) exhibit strong field-enhancement and spectral tunability, ...

DOAJ Open Access (DOAJ) DOI: 10.3390/nano16080486