Academic Articles & Research Papers

Pattern Recognition with Artificial Intelligence in Space Experiments

The application of advanced Artificial Intelligence (AI) techniques in astroparticle experiments represents a major advancement in both data analysis and experimental design. As space missions become increasingly complex, integrating AI too...

Lightweight Anonymous Group Authentication and Quantum-Cloud Key Distribution Based on PUF for Classical Network Environments

With the rapid development of quantum computing, in response to its disruptive threats to traditional cryptosystems and the urgent demand for lightweight and highly scalable secure group communication among resource-constrained devices in l...

Distinct Shifts in Microbiota Composition during Drosophila Aging Impair Intestinal Function and Drive Mortality

Alterations in the composition of the intestinal microbiota have been correlated with aging and measures of frailty in the elderly. However, the relationships between microbial dynamics, age-related changes in intestinal physiology, and org...

Molecular monitoring of insecticide resistance in major disease vectors in Armenia

Abstract Background Armenia is considered particularly vulnerable to life-threatening vector-borne diseases (VBDs) including malaria, West Nile virus disease and leishmaniasis. However, information relevant for the control of the vectors of...

Challenges in myeloperoxidase quantification: the inadequacies of current colorimetric approaches

The human lung microbiome progressively diminishes in the distal alveolar regions

Abstract Extensive investigations with sequencing methods demonstrate a large and diverse microbiome even in profound areas of the lung. However, there is still substantial lack of cultivation-based evidence and of the viability of the resi...

Low Pathogenic Avian Influenza H9N2 Viruses in Morocco: Antigenic and Molecular Evolution from 2021 to 2023

Avian influenza viruses pose significant threats to both the poultry industry and public health worldwide. Among them, the H9N2 subtype has gained substantial attention due to its high prevalence, especially in Asia, the Middle East, and Af...

Health and Cellular Impacts of Air Pollutants: From Cytoprotection to Cytotoxicity

Air pollution as one of the ravages of our modern societies is primarily linked to urban centers, industrial activities, or road traffic. These atmospheric pollutants have been incriminated in deleterious health effects by numerous epidemio...

MOLECULAR BIOLOGY OF THE MYCOBACTERIA

The molecular biology of the mycobacteria is poised at the threshold of making major contributions to the understanding of the biochemistry and pathogenic mechanisms involved in mycobacterial infections.The application of molecular biology ...

Toll-like receptor 2 coordinates induction of IL-22 in lung macrophages following organic dust-induced inflammation

IntroductionOrganic dust exposures, particularly in occupational settings, induce airway inflammation and contribute to the development and progression of chronic lung disease and impaired tissue regeneration. Interleukin-22 (IL-22) is a pl...

S1 Subunit of Spike Protein from a Current Highly Virulent Porcine Epidemic Diarrhea Virus Is an Important Determinant of Virulence in Piglets

Base on the sequence of S genes, which encode spike proteins, we previously identified three different types (North American, S INDEL, and S large-DEL types) of porcine epidemic diarrhea virus (PEDV) that have re-emerged in Japan since 2013...

Glycosylation of Epigallocatechin Gallate by Engineered Glycoside Hydrolases from <i>Talaromyces amestolkiae</i>: Potential Antiproliferative and Neuroprotective Effect of These Molecules

Glycoside hydrolases (GHs) are enzymes that hydrolyze glycosidic bonds, but some of them can also catalyze the synthesis of glycosides by transglycosylation. However, the yields of this reaction are generally low since the glycosides formed...

Protocol to induce de novo lipid droplets in Saccharomyces cerevisiae

Summary: The mechanisms underlying lipid droplet (LD) biogenesis in the endoplasmic reticulum are not completely understood. Here, we present a protocol for inducing de novo LDs containing either triacylglycerol (TAG) or sterol esters (SE) ...

Molecular Biology and Biotechnology

One of the exciting aspects of being involved in the field of molecular biology is the ever-accelerating rate of progress, both in the development of new methodologies and the practical applications of these methodologies. This popular text...

The evolution of molecular biology into systems biology

Computational Molecular Biology

In one of the first major texts in the emerging field of computational molecular biology, Pavel Pevzner covers a broad range of algorithmic and combinatorial topics and shows how they are connected to molecular biology and to biotechnology....

Targeting Inflammation With Nanosized Drug Delivery Platforms in Cardiovascular Diseases: Immune Cell Modulation in Atherosclerosis

Atherosclerosis (AS) is a disorder of large and medium-sized arteries; it consists in the formation of lipid-rich plaques in the intima and inner media, whose pathophysiology is mostly driven by inflammation. Currently available interventio...

Nanotechnology and biosensors

Engineered Chiral Probiotics Ameliorate MASH via Gut-Liver Axis.

Design Considerations for a Distributed Low-Cost Air Quality Sensing System for Urban Environments in Low-Resource Settings

With rapid urbanization, hazardous environmental exposures such as air, noise, plastic, soil and water pollution have emerged as a major threat to urban health. Recent studies show that 9 out of 10 people worldwide breathe contaminated air ...