Academic Articles & Research Papers

Unsupervised machine learning identifies distinct ALS molecular subtypes in post-mortem motor cortex and blood expression data

Abstract Amyotrophic lateral sclerosis (ALS) displays considerable clinical and genetic heterogeneity. Machine learning approaches have previously been utilised for patient stratification in ALS as they can disentangle complex disease lands...

An automated deep learning framework for brain tumor classification using MRI imagery

Abstract The precise and timely diagnosis of brain tumors is essential for accelerating patient recovery and preserving lives. Brain tumors exhibit a variety of sizes, shapes, and visual characteristics, requiring individualized treatment s...

Radiomics and radiogenomics: extracting more information from medical images for the diagnosis and prognostic prediction of ovarian cancer

Abstract Ovarian cancer (OC) remains one of the most lethal gynecological malignancies globally. Despite the implementation of various medical imaging approaches for OC screening, achieving accurate differential diagnosis of ovarian tumors ...

Artificial intelligence in glaucoma

PURPOSE OF REVIEW: The use of computers has become increasingly relevant to medical decision-making, and artificial intelligence methods have recently demonstrated significant advances in medicine. We therefore provide an overview of curren...

A review of optimization strategies for deep and machine learning in diabetic macular edema

Diabetic macular edema (DME) is a primary contributor to visual impairment in diabetic patients, necessitating precise and prompt analysis for optimal treatment. Recent breakthroughs in deep learning (DL) and machine learning (ML) have yiel...

Predictive digital twin for optimizing patient-specific radiotherapy regimens under uncertainty in high-grade gliomas

We develop a methodology to create data-driven predictive digital twins for optimal risk-aware clinical decision-making. We illustrate the methodology as an enabler for an anticipatory personalized treatment that accounts for uncertainties ...

Prediction of homologous recombination deficiency from routine histology with attention-based multiple instance learning in nine different tumor types

Abstract Background Homologous recombination deficiency (HRD) is recognized as a pan-cancer predictive biomarker that potentially indicates who could benefit from treatment with PARP inhibitors (PARPi). Despite its clinical significance, HR...

Artificial Intelligence and Acute Stroke Imaging

Artificial intelligence technology is a rapidly expanding field with many applications in acute stroke imaging, including ischemic and hemorrhage subtypes. Early identification of acute stroke is critical for initiating prompt intervention ...

The potential for artificial intelligence in healthcare

The complexity and rise of data in healthcare means that artificial intelligence (AI) will increasingly be applied within the field. Several types of AI are already being employed by payers and providers of care, and life sciences companies...

Health Equity Journal: Special Issue Guest Editorial

The practices of contemporary clinical decision-making and care rely heavily on racial biological essentialism, which is a set of ideas originating in modern science that describes populations as comprising distinct subpopulations with uniq...

Preoperative and Prognostic Prediction of Microvascular Invasion in Hepatocellular Carcinoma: A Review Based on Artificial Intelligence

Microvascular invasion of hepatocellular carcinoma is an important factor affecting tumor recurrence after liver resection and liver transplantation. There are many ways to classify microvascular invasion, however, an international consensu...

Impact of AI-quantified fluid dynamics on visual outcomes over 5 years in patients with treatment-naïve nAMD from the FRB! registry

Abstract To investigate the impact of retinal fluid dynamics on visual outcomes in patients with treatment-naïve neovascular age-related macular degeneration (nAMD) treated in the real world over 5 years using approved AI-based fluid monito...

Artificial intelligence revolutionizing anesthesia management: advances and prospects in intelligent anesthesia technology

With the development of artificial intelligence (AI), AI-related technologies are being applied in many fields of medicine. Anesthesia is now widely used in surgery, emergency resuscitation, pain treatment and other fields. However, differe...

Sex-based differences in characteristics, management, and outcomes in heart failure with reduced ejection fraction

Heart failure with reduced ejection fraction (HFrEF) exhibits significant sex-based differences in clinical presentation, management, and outcomes. This study aimed to evaluate these differences using data from the Swedish Heart Failure Reg...

Artificial Intelligence and Personalized Medicine

Rehabilitation Wearable Boots and Offloading Methods for Diabetic Foot Ulcer Treatment: A Systematic Review.

Effect of robot-assisted gait training combined with electroacupuncture on lower limb motor function and brain network characteristics in stroke: an EEG study

Abstract Background Stroke survivors often experience residual motor dysfunction in their limbs. Additional physical rehabilitation therapies may further improve patients’ functional outcomes. By combining direct interventions targeting the...

An Ensemble Machine Learning Model for Early Prediction of Vancomycin-Induced Acute Kidney Injury in ICU Patients

Introduction: Acute Kidney Injury (AKI) is a severe complication of vancomycin treatment due to its nephrotoxic effects. However, research on predicting AKI in this high-risk group remains limited. This study presents a stacking ensemble ma...

Artificial intelligence assisted 3D in the robotic urooncology? A systematic review and narrative synthesis of current applications, challenges and future directions

Background: Artificial intelligence (AI)-assisted three-dimensional (3D) surgical platforms, integrated with augmented reality, have the potential to improve intraoperative anatomical recognition and provide surgeons with an immersive, dyna...

Advances in proton therapy technology and global clinical applications

Proton therapy, by leveraging its unique physical characteristic of the Bragg peak, enables high-precision dose delivery to the tumor target while effectively protecting surrounding normal tissues, and has become an important representative...