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Academic Articles & Research Papers
Showing 20 of 1,739 academic articles
Hongqin Chen, Jian Meng, Qiao Li, Xin Luo et al. • Health and Quality of Life Outcomes
(2025)
Abstract Background The heterogeneity of patient-reported outcomes (PROs) and patient-reported outcome measures (PROMs) in published clinical studies on vaginal relaxation syndrome (VRS) hinders cross-study comparisons and integration of ev...
DOAJ
Open Access (DOAJ)
DOI: 10.1186/s12955-025-02432-5
Yanshang Wang, Xiaoping Wei • BMJ Open
(2026)
Introduction Electronic patient-reported outcome (ePROs)-based symptom monitoring benefits health-related quality of life (HRQoL) in various cancers. However, despite the high disease and economic burden of hepatocellular carcinoma (HCC) an...
DOAJ
Open Access (DOAJ)
DOI: 10.1136/bmjopen-2026-116199
Jiaohong Liu, Haohao Wang, May Lei Mei, Chloe Meng Jiang et al. • Dentistry Journal
(2026)
Dental caries, as a common chronic disease with high global prevalence, has undergone a paradigm shift from a traditional treatment-oriented model to a management approach focused on controlling caries risk factors while implementing person...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/dj14070430
Zhou C, Li X, Shen W, Huang Q et al. • Risk Management and Healthcare Policy
(2024)
Chi Zhou,1,* Xu Li,1,* Wenli Shen,2 Qunfang Huang,1 Xiaoling Lin,1 Gaofeng Zhang,3 Yin Dong3,4 1Department of Health Management, School of Public Health, Hangzhou Normal University, Hangzhou, Zhejiang, People’s Republic of China; 2D...
DOAJ
Open Access (DOAJ)
Wei Song, Xiao Yang, Liu Yang, Yan Ren et al. • BMJ Open
(2025)
Objective This study aimed to identify body mass index (BMI) growth trajectories from birth to 24 months of age and examine the independent and additive effects of four maternal metabolic risk factors, namely prepregnancy BMI, the rate of g...
DOAJ
Open Access (DOAJ)
DOI: 10.1136/bmjopen-2024-088641
Ruijie Tang, Peiqi Zhu, Ruxue Yan, Yaping Zhou et al. • Digital Health
(2025)
Objectives Urinary tract infections (UTIs) frequently affect individuals of all ages, necessitating antibiotic treatment and medical care, which can impair quality of life and cause psychological strain. Online Health Consultation (OHC) pla...
DOAJ
Open Access (DOAJ)
DOI: 10.1177/20552076251393289
ZHAO Runze, YU Haiyang, HAN Xu • Zhongguo quanke yixue
(2022)
Cuba has a three-level healthcare system, and offers free universal healthcare, of which community health services occupy a decisive position. Cuba has accumulated abundant experience in implementing public health services, primary healthca...
DOAJ
Open Access (DOAJ)
DOI: 10.12114/j.issn.1007-9572.2021.00.233
Huitao Li, Lei Fu, Xueyu Chen, Heng Xu et al. • Frontiers in Cellular and Infection Microbiology
(2022)
Intrauterine infection is linked to adverse pregnancy outcomes in pregnant women. Neonates from parturients with intrauterine infection are usually treated with antibiotics, but their gut microbiota and metabolome are seldom studied. In thi...
DOAJ
Open Access (DOAJ)
DOI: 10.3389/fcimb.2022.817832
Qian YF, Geng GL, Ren YQ, Zhang XT et al. • Risk Management and Healthcare Policy
(2021)
Yu-Fei Qian,1 Gui-Ling Geng,1 Yu-Qin Ren,2 Xin-Tong Zhang,2 Wen-Jun Sun,2 Qing Li2 1Department of School of Nursing, Nantong University Medical School, Nantong, 226001, People’s Republic of China; 2Department of Emergency, Nantong First Peo...
DOAJ
Open Access (DOAJ)
Dandan Wang, Chang Xu, Wenxiao Wang, Hui Lu et al. • Brain Sciences
(2022)
Allele 4 of the apolipoprotein E gene (APOE ε4) and hypertension are considered risk factors for Alzheimer’s Disease (AD). The detection of differences in cognitive function and brain networks between hypertensive patients who are APOE ε4 c...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/brainsci12050515
Ruichen Su, Tian Zhou • Frontiers in Aging Neuroscience
(2021)
Parkinson’s disease (PD) is a neurodegenerative disorder closely related to immunity. An important aspect of the pathogenesis of PD is the interaction between α-synuclein and a series of immune cells. Studies have shown that accumulation of...
DOAJ
Open Access (DOAJ)
DOI: 10.3389/fnagi.2021.769506
Fei Wang, Fei Wang, Min Fei, Min Fei et al. • Frontiers in Neuroscience
(2022)
BackgroundConstipation and dementia have similar epidemiological characteristics. Changes in intestinal flora and characteristics of the brain-gut axis play roles in the pathogeneses of the two diseases, suggesting that there may be a close...
DOAJ
Open Access (DOAJ)
DOI: 10.3389/fnins.2021.821654
Sijie Li, Sijie Li, Changhong Ren, Changhong Ren et al. • Frontiers in Genetics
(2020)
Hypoxic/ischemic preconditioning (HPC/IPC) is an innate neuroprotective mechanism in which a number of endogenous molecules are known to be involved. Tuberous sclerosis complex 1 (TSC1), also known as hamartin, is thought to be one such mol...
DOAJ
Open Access (DOAJ)
DOI: 10.3389/fgene.2020.582368
Chuan Wang, Qian Wang, Guangming Xu, Guangming Xu et al. • Frontiers in Molecular Neuroscience
(2024)
Prolonged or repeated exposure to stress elevates the risk of various psychological diseases, many of which are characterized by central nervous system dysfunction. Recent studies have demonstrated that circular RNAs (circRNAs) are highly a...
DOAJ
Open Access (DOAJ)
DOI: 10.3389/fnmol.2024.1381098
Qinyang Yu, Qinyang Yu, Wangyang Liu, Wangyang Liu et al. • Frontiers in Cellular Neuroscience
(2021)
Stroke is one of the leading causes of death and disability worldwide. However, there is a lack of effective medications to speed up the recovery process. Ischemic stroke, as the result of cerebral infarction or cerebral artery narrowing, i...
DOAJ
Open Access (DOAJ)
DOI: 10.3389/fncel.2021.757670
Zhong-Qi Bu, Hai-Yang Yu, Jue Wang, Xin He et al. • ASN Neuro
(2021)
Ischemic stroke is one of the main causes of high morbidity, mortality, and disability worldwide; however, the treatment methods are limited and do not always achieve satisfactory results. The pathogenesis of ischemic stroke is complex, def...
DOAJ
Open Access (DOAJ)
DOI: 10.1177/17590914211037505
Su Y, Bi T, Gong G, Jiang Q et al. • Psychology Research and Behavior Management
(2019)
Yanhua Su,1 Taiyong Bi,1 Gaolang Gong,2,3 Qiu Jiang,4,5 Hong Chen4,5 1Center for Mental Health Research in School of Management, Zunyi Medical University, Zunyi 563000, People’s Republic of China; 2State Key Laboratory of Cognitive Ne...
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Open Access (DOAJ)
Muhammad Umair, Muhammad Younus, Sarfraz Shafiq, Anam Nayab et al. • Frontiers in Genetics
(2022)
Spondylocostal dysostosis is a genetic defect associated with severe rib and vertebrae malformations. In recent years, extensive clinical and molecular diagnosis advancements enabled us to identify disease-causing variants in different gene...
DOAJ
Open Access (DOAJ)
DOI: 10.3389/fgene.2022.996364
Kunpeng Liu, Haitao Gong, Binbin Jiao, Zhenshan Ding et al. • Advanced NanoBiomed Research
(2024)
This study aims to evaluate the therapeutic potential of cationic liposomal neostigmine bromide (NB), a novel drug delivery system, for the treatment of detrusor underactivity. By comparing the characteristics of NB‐liposomes (NLP), NB‐β‐cy...
DOAJ
Open Access (DOAJ)
DOI: 10.1002/anbr.202300109
Zelin Tian, Chen Xu, Peijun Yang, Zhibin Lin et al. • Frontiers in Immunology
(2022)
Hepatocellular carcinoma(HCC) is the sixth most common cancer in the world and is usually caused by viral hepatitis (HBV and HCV), alcoholic, and non-alcoholic fatty liver disease(NAFLD). Viral hepatitis accounts for 80% of HCC cases worldw...
DOAJ
Open Access (DOAJ)
DOI: 10.3389/fimmu.2022.984728