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Academic Articles & Research Papers
Showing 20 of 4,247 academic articles
Adam H. Tencer, Jiuyang Liu, Jing Zhu, Nathaniel T. Burkholder et al. • Scientific Reports
(2022)
Abstract The E3 ubiquitin ligase HERC2 has been linked to neurological diseases and cancer, however it remains a poorly characterized human protein. Here, we show that the ZZ domain of HERC2 (HERC2ZZ) recognizes a mimetic of the Nt-R cargo ...
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Open Access (DOAJ)
DOI: 10.1038/s41598-022-10119-w
Joseph Hibbeln, Steven Gregory, Yasmin Iles-Caven, Caroline M. Taylor et al. • Environment International
(2018)
There is a public perception that relatively low doses of mercury found in seafood are harmful to the fetal brain but little consistent evidence to support this. In earlier publications we have shown no adverse associations between maternal...
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Open Access (DOAJ)
DOI: 10.1016/j.envint.2018.03.024
Victoria Vitkova, Vesela Yordanova, Galya Staneva, Ognyan Petkov et al. • Membranes
(2021)
Simple carbohydrates are associated with the enhanced risk of cardiovascular disease and adverse changes in lipoproteins in the organism. Conversely, sugars are known to exert a stabilizing effect on biological membranes, and this effect is...
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Open Access (DOAJ)
DOI: 10.3390/membranes11110847
Stefania Martucciello, Marchesa Bilio, Sara Cioffi, Ilaria Aurigemma et al. • Journal of Cardiovascular Development and Disease
(2026)
Gene inactivation in model organisms has identified numerous genes and signaling pathways involved in mammalian cardiac outflow tract (OFT) development. Human genetics data have implicated the VEGFR3 gene in OFT development, but when and wh...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/jcdd13080399
Maria Angelova, Petko Alov, Ivanka Tsakovska, Dessislava Jereva et al. • Molecules
(2025)
Scoring functions are key elements in docking protocols as they approximate the binding affinity of a ligand (usually a small bioactive molecule) by calculating its interaction energy with a biomacromolecule (usually a protein). In this stu...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/molecules30132777
Li Rong, Haiyu Li, Zhaodong Li, Jing Ouyang et al. • Frontiers in Medicine
(2020)
Background and Objective: Chemotherapy and radiotherapy are effective treatment options for cervical cancer (CC), but their efficacy is limited by short survival rate of about 5 years particularly for advance stage CC. Bioinformatics analys...
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Open Access (DOAJ)
DOI: 10.3389/fmed.2020.608441
Balamurugan Jagadeesan, Leen Baert, Martin Wiedmann, Renato H. Orsi • Frontiers in Microbiology
(2019)
As WGS is increasingly used by food industry to characterize pathogen isolates, users are challenged by the variety of analysis approaches available, ranging from methods that require extensive bioinformatics expertise to commercial softwar...
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Open Access (DOAJ)
DOI: 10.3389/fmicb.2019.00947
Xhulio Dhori, Silvia Gioiosa, Stefania Gonfloni • Scientific Data
(2024)
Abstract Granulosa cells (GCs) play crucial roles in oocyte maturation. Through gap junctions and extracellular vesicles, they mediate the exchange of molecules such as microRNAs and messenger RNAs. Different ovarian cell types exhibit uniq...
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Open Access (DOAJ)
DOI: 10.1038/s41597-024-03715-0
Wei Sha, Timothy Bertram, Deepak Jain, Cory Brouwer et al. • Stem Cell Research & Therapy
(2022)
Abstract Background Selected renal cells (SRC) are in Phase II clinical trials as a kidney-sourced, autologous, tubular epithelial cell-enriched cell-based therapy for chronic kidney disease (CKD). In preclinical studies with rodent models ...
DOAJ
Open Access (DOAJ)
DOI: 10.1186/s13287-022-02713-6
O. A. Gromova, I. Yu. Torshin, A. G. Moiseenok • Фармакоэкономика
(2025)
Background. Neurotransmitter adenosine and B-group vitamins have neuroprotective, remyelinizing and anti-neuroinflammatory properties. Despite the studies of these molecules for decades, the molecular mechanisms of their synergistic effect ...
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Open Access (DOAJ)
DOI: 10.17749/2070-4909/farmakoekonomika.2024.285
Shih-Ho Wang, Chin-Hu Wu, Chin-Chuan Tsai, Tai-Yu Chen et al. • Current Issues in Molecular Biology
(2022)
Taraxacum officinale (dandelion) is often used in traditional Chinese medicine for the treatment of cancer; however, the downstream regulatory genes and signaling pathways mediating its effects on breast cancer remain unclear. The present s...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/cimb44050142
Sven Warris, Elio Schijlen, Henri van de Geest, Rahulsimham Vegesna et al. • BMC Genomics
(2018)
Abstract Background Next-generation sequencing requires sufficient DNA to be available. If limited, whole-genome amplification is applied to generate additional amounts of DNA. Such amplification often results in many chimeric DNA fragments...
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Open Access (DOAJ)
DOI: 10.1186/s12864-018-5164-1
Brianna Dufek, Daniel T Meehan, Duane Delimont, Kevin Wilhelm et al. • PLoS ONE
(2020)
Previous work demonstrates that the hearing loss in Alport mice is caused by defects in the stria vascularis. As the animals age, progressive thickening of strial capillary basement membranes (SCBMs) occurs associated with elevated levels o...
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Open Access (DOAJ)
DOI: 10.1371/journal.pone.0237907
Jing Yang, Pengfei Li, Pengfei Li, Pengfei Li et al. • Frontiers in Immunology
(2022)
ObjectiveExtranodal natural killer/T cell lymphoma (NKTCL) is an aggressive EBV-related lymphoma, originating from NK cells or T cells. Previous study demonstrated that CD56 negative NKTCL should be recognized as a distinct subtype. In this...
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Open Access (DOAJ)
DOI: 10.3389/fimmu.2022.829366
Cheng J, Huang Y • Journal of Inflammation Research
(2026)
Jian Cheng, Yangfeng Huang Department of Traditional Chinese Medicine, Sichuan Provincial People’s Hospital, School of Medicine,University of Electronic Science and Technology of China, Chengdu, Sichuan, People’s Republic of ChinaCorrespond...
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Open Access (DOAJ)
Wentong Chen, Mengxiao Ge, Shuangyi Sun, Hanxiao Zhang et al. • Scientific Reports
(2025)
Abstract As critical precursors to colorectal cancer (CRC), high-risk colorectal adenomas (HR-CRAs) lack effective chemopreventive strategies beyond endoscopic resection. We previously established a standardized protocol for culturing patie...
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Open Access (DOAJ)
DOI: 10.1038/s41598-025-32406-y
Zhengyi Zhu, Glen A. Satten, Caroline Mitchell, Yi-Juan Hu • Microbiome
(2021)
Abstract Background Matched-set data arise frequently in microbiome studies. For example, we may collect pre- and post-treatment samples from a set of individuals, or use important confounding variables to match data from case participants ...
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Open Access (DOAJ)
DOI: 10.1186/s40168-021-01034-9
Lin J, Xue Y, Su W, Zhang Z et al. • International Journal of COPD
(2022)
Jie Lin,1,2,* Yanlong Xue,1,2,* Wenyan Su,1,2,* Zan Zhang,1,2 Qiu Wei,1,2 Tianxia Huang1,2 1Department of Respiratory and Critical Care, The Fifth Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, 530022, Peop...
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Open Access (DOAJ)
Qiang Wang, Qiang Wang, Yujun Ji, Torkel B. Brismar et al. • Frontiers in Surgery
(2021)
Background: To evaluate the feasibility and efficacy of sequential portal vein embolization (PVE) and radiofrequency ablation (RFA) (PVE+RFA) as a minimally invasive variant for associating liver partition and portal vein ligation for stage...
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Open Access (DOAJ)
DOI: 10.3389/fsurg.2021.741352
Müjgan Ercan, Emiş Deniz Akbulut, Ayşen Caniklioğlu, Esra Fırat Oğuz et al. • Journal of Mass Spectrometry and Advances in the Clinical Lab
(2025)
Introduction: Free amino acid (FAA) analysis plays a crucial role in diagnosing and monitoring inborn errors of metabolism, assessing nutritional status, and identifying metabolic imbalances associated with various diseases. This study aime...
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Open Access (DOAJ)
DOI: 10.1016/j.jmsacl.2025.04.010