Academic Articles & Research Papers

Digital prevention of depression for farmers? A qualitative study on participants' experiences regarding determinants of acceptance and satisfaction with a tailored guided internet intervention program

Introduction: Farmers, forest workers and gardeners have a higher risk of developing depression compared to other occupational populations. As part of the German pilot project “With us in balance”, the potential of six guided internet- and ...

Progress and Perspective of CRISPR‐Cas9 Technology in Translational Medicine

Abstract Translational medicine aims to improve human health by exploring potential treatment methods developed during basic scientific research and applying them to the treatment of patients in clinical settings. The advanced perceptions o...

Adopting AI Enhances Humanitarian Operations While Demanding Critical Trade-Offs

Artificial intelligence (AI) is increasingly impacting the cooperation sector, transforming how humanitarians are operating in the field. AI tools now allow for improved health diagnostics and quality services. In conflict areas, organizati...

Wellbeing intervention for chronic kidney disease (WICKD): a randomised controlled trial study protocol

Abstract Background Incidence of end stage kidney disease (ESKD) for Indigenous Australians is especially high in remote and very remote areas of Australia (18 and 20 times the rate of comparable non-Indigenous people). Relocating away from...

Essential requirement of complex number for oscillatory phenomenon in intracellular trafficking process

Intracellular protein trafficking processes consisting of three intracellular states are described by three differential equations. To solve the equations, a quadratic equation is required, and its roots are generally real or complex. The p...

The Family Wellness Program: a bench to bedside translation of behavioral and social science research into a clinical program for intimate partners of warfighters following traumatic brain injury

This report details a bench to bedside translation of behavioral and social science research into a clinical program as a result of a collaboration between two United States Defense Health Agency Centers of Excellence for warfighter traumat...

A “P5” Approach to Healthcare and Health Technology

Abstract The challenges represented by chronic conditions worldwide are related to disease management and patient engagement. Healthcare should open not only to new tools and resources but also to innovative approaches. This contribution de...

Advanced Digital Health Technologies for COVID-19 and Future Emergencies

Background: Coronavirus disease 2019 (COVID-19) has led to a national health care emergency in the United States and exposed resource shortages, particularly of health care providers trained to provide critical or intensive care. This artic...

Epidermal Growth Factor Induces Vasoconstriction Through the Phosphatidylinositol 3-Kinase-Mediated Mitogen-Activated Protein Kinase Pathway in Hypertensive Rats

Abstract.: We investigated whether increased contractile responsiveness to epidermal growth factor (EGF) is associated with altered activation of mitogen-activated protein kinase (MAPK) in the aortic smooth muscle of deoxycorticosterone ace...

Effectiveness of a tele-rehabilitation intervention to improve performance and reduce morbidity for people post hip fracture - study protocol for a randomized controlled trial

Abstract Background Most surviving hip-fracture patients experience reduced mobility and lose some of their functional ability, which increases the risk of complications and rehospitalization. Post-discharge transitional programs to reduce ...

Neurological Manifestations of SARS-CoV-2 Infection: Protocol for a Sub-analysis of the COVID-19 Critical Care Consortium Observational Study

IntroductionNeurological manifestations and complications in coronavirus disease-2019 (COVID-19) patients are frequent. Prior studies suggested a possible association between neurological complications and fatal outcome, as well as the exis...

Fractional exhaled nitric oxide as a potential biomarker for radiation pneumonitis in patients with non-small cell lung cancer: A pilot study

Introduction: The aim of the study was to investigate repetitive fractional exhaled nitric oxide (FeNO) measurements during high-dose radiation therapy (HDRT) and to evaluate the use of FeNO to predict symptomatic radiation pneumonitis (RP)...

An adaptive cruise control system for autonomous vehicles using PRDC–CoROA-based hybrid optimization

Abstract An adaptive cruise control (ACC) system has a key role to play in enhancing the safety and stability of autonomous vehicles, along with ensuring improved ride quality through proper management of vehicle velocity and distance betwe...

Digital health technologies and major depressive disorder

There is an urgent need to improve the clinical management of major depressive disorder (MDD), which has become increasingly prevalent over the past two decades. Several gaps and challenges in the awareness, detection, treatment, and monito...

Defining the future of health technology: biomechatronics.

Future progress in healthcare and medicine depends on today's investment in research, development, and education. We cannot leave such urgent issues to determine themselves, but rather must actively collaborate to ensure a stable healthcare...

Health Technology Assessment. Methodologies for Developing Countries

Evaluative research in area of health technology assessment (HTA) and training of researchers in medicine schools of public health and training programs in health management should be promoted. The focus when evaluating health technology in...

Mobile Health Technology to Improve Care for Patients With Atrial Fibrillation

Feasibility study for interactive reporting of network meta-analysis: experiences from the development of the MetaInsight COVID-19 app for stakeholder exploration, re-analysis and sensitivity analysis from living systematic reviews

Abstract Background Network meta-analysis (NMA) has been increasingly adopted worldwide by Cochrane reviews, guideline developers and decision-making bodies to identify optimal treatment choices. However, NMA results are often produced stat...

Social norms, misperceptions, and mosquito net use: a population-based, cross-sectional study in rural Uganda

Abstract Background Mosquito net use is an essential part of malaria prevention. Although previous research has shown that many people sleep under a mosquito net in endemic areas, it is unknown whether people underestimate how common it is ...

Treatment of Gluteal Tendinopathy: A Systematic Review and Stage-Adjusted Treatment Recommendation

Background: Gluteal tendinopathy is the most common lower limb tendinopathy. It presents with varying severity but may cause debilitating lateral hip pain. Purpose: To review the therapeutic options for different stages of gluteal tendinopa...