Academic Articles & Research Papers

Using deep learning to predict tyrosinase inhibitors for treating hyperpigmentation disorders

Background In recent years, skin health has garnered widespread attention, with hyperpigmentation disorders caused by excessive melanin deposition emerging as a particularly prominent concern. Tyrosinase, as the rate-limiting enzyme in the ...

V-Shape Lumbar Bridge: postural reduction combined with percutaneous vertebroplasty for the treatment of osteoporotic compression fractures.

Automated segmentation of brain metastases in T1-weighted contrast-enhanced MR images pre and post stereotactic radiosurgery

Abstract Background and purpose Accurate segmentation of brain metastases on Magnetic Resonance Imaging (MRI) is tedious and time-consuming for radiologists that could be optimized with deep learning (DL). Previous studies assessed several ...

Complications and Management of Deep Anterior Lamellar Keratoplasty

Objectives: To report the intraoperative and postoperative follow-up complications and management of these in deep anterior lamellar keratoplasty (DALK) surgery. Materials and Methods: Two hundred eighty-four eyes of 252 patients followed...

The Microbiome Composition of a Man's Penis Predicts Incident Bacterial Vaginosis in His Female Sex Partner With High Accuracy

Background: We determined the predictive accuracy of penile bacteria for incident BV in female sex partners. In this prospective cohort, we enrolled Kenyan men aged 18–35 and their female sex partners aged 16 and older. We assessed BV at ba...

A Cardiovascular Disease Prediction Model Based on Routine Physical Examination Indicators Using Machine Learning Methods: A Cohort Study

BackgroundCardiovascular diseases (CVD) are currently the leading cause of premature death worldwide. Model-based early detection of high-risk populations for CVD is the key to CVD prevention. Thus, this research aimed to use machine learni...

Machine Learning Methods in the Environmental Sciences

Machine learning methods originated from artificial intelligence and are now used in various fields in environmental sciences today. This is the first single-authored textbook providing a unified treatment of machine learning methods and th...

Robust optical metasurface heterostructures for prevention and treatment of peri-implantitis.

A machine-learning approach for predicting the effect of carnitine supplementation on body weight in patients with polycystic ovary syndrome

The present study aimed to explore the effect of carnitine supplementation on body weight in patients with polycystic ovary syndrome (PCOS) and predict an appropriate dosage schedule using a machine-learning approach. Data were obtained fro...

CViewer: a Java-based statistical framework for integration of shotgun metagenomics with other omics datasets

Abstract Background Shotgun metagenomics for microbial community survey recovers enormous amount of information for microbial genomes that include their abundances, taxonomic, and phylogenetic information, as well as their genomic makeup, t...

A review of the application of machine learning in water quality evaluation

With the rapid increase in the volume of data on the aquatic environment, machine learning has become an important tool for data analysis, classification, and prediction. Unlike traditional models used in water-related research, data-driven...

Deciphering Exhaled Aerosol Fingerprints for Early Diagnosis and Personalized Therapeutics of Obstructive Respiratory Diseases in Small Airways

Respiratory diseases often show no apparent symptoms at their early stages and are usually diagnosed when permanent damages have been made to the lungs. A major site of lung pathogenesis is the small airways, which make it highly challengin...

Automated cell type annotation and exploration of single-cell signaling dynamics using mass cytometry

Summary: Mass cytometry by time-of-flight (CyTOF) is an emerging technology allowing for in-depth characterization of cellular heterogeneity in cancer and other diseases. Unfortunately, high-dimensional analyses of CyTOF data remain quite d...

Machine learning in pain research

1. Introduction Pain and pain chronification are incompletely understood and unresolved medical problems that continue to have a high prevalence.14 It has been accepted that pain is a complex phenomenon.2,32,72 Contemporary methods of compu...

Identification of immune-associated biomarkers of diabetes nephropathy tubulointerstitial injury based on machine learning: a bioinformatics multi-chip integrated analysis

Abstract Background Diabetic nephropathy (DN) is a major microvascular complication of diabetes and has become the leading cause of end-stage renal disease worldwide. A considerable number of DN patients have experienced irreversible end-st...

Dynamic Monitoring of Thyroid-Stimulating Hormone Receptor Antibody and Extraocular Muscle Thickness: A Clinical Risk Stratification Model for Recurrence Risk Post-Glucocorticoid Therapy in TED Patients

Yaling Li, Xiuhong Yang, Shuli Hu Department of Intensive Care Unit, Wuhan No. 1 Hospital, Wuhan, 430022, People’s Republic of ChinaCorrespondence: Shuli Hu, Department of Intensive Care Unit, Wuhan No. 1 Hospital, No. 215 Zhongshan Avenue,...

A First Course in Machine Learning

"A First Course in Machine Learning by Simon Rogers and Mark Girolami is the best introductory book for ML currently available. It combines rigor and precision with accessibility, starts from a detailed explanation of the basic foundations ...

Machine Learning and the Future of Cardiovascular Care

The role of physicians has always been to synthesize the data available to them to identify diagnostic patterns that guide treatment and follow response. Today, increasingly sophisticated machine learning algorithms may grow to support clin...

Machine Learning Approaches for Clinical Psychology and Psychiatry

Machine learning approaches for clinical psychology and psychiatry explicitly focus on learning statistical functions from multidimensional data sets to make generalizable predictions about individuals. The goal of this review is to provide...

Prediction of Drug Targets for Specific Diseases Leveraging Gene Perturbation Data: A Machine Learning Approach

Identification of the correct targets is a key element for successful drug development. However, there are limited approaches for predicting drug targets for specific diseases using omics data, and few have leveraged expression profiles fro...