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Handbook of Plant Science

NIGEL J. CHAFFEY • Annals of Botany (2008)

At a bookshelf-bending 4·5 kg, a bank-balance-denting £250, edited by a highly distinguished plant scientist, and released in the publisher's bicentenary year, you are entitled to expect something really special from this Handbook of Plant ...

OPENALEX Open Access DOI: https://doi.org/10.1093/aob/mcm330

Nanosensor Applications in Plant Science

Daniel Steven Shaw, Kevin C. Honeychurch • Biosensors (2022)

Plant science is a major research topic addressing some of the most important global challenges we face today, including energy and food security. Plant science has a role in the production of staple foods and materials, as well as roles in...

OPENALEX cc-by DOI: https://doi.org/10.3390/bios12090675 PMC: 9496508

Deciphering an AgRP-serotoninergic neural circuit in distinct control of energy metabolism from feeding

Yong Han, Guobin Xia, Dollada Srisai, Fantao Meng et al. • Nature Communications (2021)

Neuronal signaling has an important role in the regulation of energy expenditure and body weight, however, the underlying mechanisms are incompletely understood. Here, the authors report a AgRP-MC4R-serotonin expressing neuronal circuit tha...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41467-021-23846-x

The Vibrio vulnificus stressosome is an oxygen-sensor involved in regulating iron metabolism

Veronika Heinz, Wenke Jäckel, Susann Kaltwasser, Laura Cutugno et al. • Communications Biology (2022)

A cryo-electron microscopy reconstruction of a stressosome complex from a Gram-negative bacterium, Vibrio vulnificus, reveals variations in subunit composition and symmetry, which could serve to adjust the activation threshold in the respon...

DOAJ Open Access (DOAJ) DOI: 10.1038/s42003-022-03548-w

Application of a novel pH-responsive gemini surfactant for delivery of curcumin molecules

Maral Rahimzadeh, Majid Sadeghizadeh, Farhood Najafi, Seyed Shahriar Arab et al. • Materials Research Express (2020)

During the last few decades, extensive studies have been conducted to elucidate the anti-cancer effects of curcumin. Despite promising results indicating curcumin could impede cancer cells ability thrive and proliferation, clinical applicat...

DOAJ Open Access (DOAJ) DOI: 10.1088/2053-1591/ab770f

Structural Design, Synthesis and Antioxidant, Antileishmania, Anti-Inflammatory and Anticancer Activities of a Novel Quercetin Acetylated Derivative

Saul Vislei Simões da Silva, Orlando Maia Barboza, Jéssica Teles Souza, Érica Novaes Soares et al. • Molecules (2021)

Quercetin (Q) is a bioflavonoid with biological potential; however, poor solubility in water, extensive enzymatic metabolism and a reduced bioavailability limit its biopharmacological use. The aim of this study was to perform structural mod...

DOAJ Open Access (DOAJ) DOI: 10.3390/molecules26226923

Atorvastatin suppresses high-risk colorectal adenomas via reprogramming of lipid metabolism and Inhibition of stemness

Wentong Chen, Mengxiao Ge, Shuangyi Sun, Hanxiao Zhang et al. • Scientific Reports (2025)

Abstract As critical precursors to colorectal cancer (CRC), high-risk colorectal adenomas (HR-CRAs) lack effective chemopreventive strategies beyond endoscopic resection. We previously established a standardized protocol for culturing patie...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-025-32406-y

Sex-based estimation of biological variation in plasma-free amino acid concentrations among healthy adults

Müjgan Ercan, Emiş Deniz Akbulut, Ayşen Caniklioğlu, Esra Fırat Oğuz et al. • Journal of Mass Spectrometry and Advances in the Clinical Lab (2025)

Introduction: Free amino acid (FAA) analysis plays a crucial role in diagnosing and monitoring inborn errors of metabolism, assessing nutritional status, and identifying metabolic imbalances associated with various diseases. This study aime...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.jmsacl.2025.04.010

Molecular docking and mouse modeling suggest CMKLR1 and INSR as targets for improving PCOS phenotypes by minocycline

Mahdie Kian, Elham Hosseini, Tooba Abdizadeh, Taimour Langaee et al. • EXCLI Journal : Experimental and Clinical Sciences (2022)

Polycystic ovary syndrome (PCOS) is the most common cause of women’s infertility. Some inflammatory pathways play a pivotal role in the pathogenesis of PCOS. This study aimed to investigate the possible beneficial effects of minocycline on ...

DOAJ Open Access (DOAJ) DOI: 10.17179/excli2021-4534

Review on: Women with Polycystic Ovary Syndrome

Neelam Gusain, Ashish P. Anjankar, Ranjit S. Ambad, Roshan K. Jha et al. • Journal of Pharmacy and Bioallied Sciences (2025)

One of the biggest health issues facing women in their childbearing years worldwide is polycystic ovarian syndrome, or PCOS. PCOS is a prevalent endocrine condition with well-known negative effects on metabolism, reproduction, and cardiovas...

DOAJ Open Access (DOAJ) DOI: 10.4103/jpbs.jpbs_1995_24

Long-Term Prognosis and Systemic Impact of Acromegaly: Analyses Utilizing Korean National Health Insurance Data

Sangmo Hong, Kyungdo Han, Cheol-Young Park • Endocrinology and Metabolism (2025)

Acromegaly is a rare endocrine disorder caused by excessive growth hormone secretion. Its low prevalence poses challenges in studying its long-term prognosis and systemic effects. To address this research gap, we conducted five studies usin...

DOAJ Open Access (DOAJ) DOI: 10.3803/EnM.2024.2285

Factors Affecting High Body Weight Variability

Kyungdo Han, Mee Kyoung Kim • Journal of Obesity & Metabolic Syndrome (2023)

Background : High body weight variability (BWV) is associated with many metabolic and cardiovascular diseases in adults. The study was designed to explore the baseline characteristics associated with high BWV. Methods : Using a nationally r...

DOAJ Open Access (DOAJ) DOI: 10.7570/jomes22063

Fatty Liver & Diabetes Statistics in Korea: Nationwide Data 2009 to 2017

Eugene Han, Kyung-Do Han, Yong-ho Lee, Kyung-Soo Kim et al. • Diabetes & Metabolism Journal (2023)

Background This study investigated the changes of fatty liver disease prevalence in general Korean population. Methods This study analyzed data from the Korean National Health Insurance Service from 2009 to 2017 that included individuals ag...

DOAJ Open Access (DOAJ) DOI: 10.4093/dmj.2022.0444

Cumulative Exposure to High γ-Glutamyl Transferase Level and Risk of Diabetes: A Nationwide Population-Based Study

Ji-Yeon Park, Kyungdo Han, Hun-Sung Kim, Jae-Hyoung Cho et al. • Endocrinology and Metabolism (2022)

Background Elevated γ-glutamyl transferase (γ-GTP) level is associated with metabolic syndrome, impaired glucose tolerance, and insulin resistance, which are risk factors for type 2 diabetes. We aimed to investigate the association of cumul...

DOAJ Open Access (DOAJ) DOI: 10.3803/EnM.2022.1416

Melatonin Regulates Lipid Metabolism in Porcine Cumulus–Oocyte Complexes via the Melatonin Receptor 2

Jun-Xue Jin, Jing-Tao Sun, Chao-Qian Jiang, Hong-Di Cui et al. • Antioxidants (2022)

Previous studies suggest that the inclusion of melatonin (MTn) in in vitro maturation protocols improves the developmental competence of oocytes by scavenging reactive oxygen species (ROS). However, the molecular mechanisms integrating mela...

DOAJ Open Access (DOAJ) DOI: 10.3390/antiox11040687

Implications of climate change on freshwater ecosystems and their biodiversity

Divya Nimma, Okram Ricky Devi, Bibek Laishram, Janjhyam Venkata Naga Ramesh et al. • Desalination and Water Treatment (2025)

Global warming is a phenomenon whereby the planet's exposure to the sun's radiation worsens from the high emission of gasses believed to trap heat within the atmosphere. Carbon dioxide (CO2) is the leading greenhouse gas majorly responsible...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.dwt.2024.100889

Sleep behaviours and associated habits and the progression of pre-diabetes to type 2 diabetes mellitus in adults: A systematic review and meta-analysis

Samiul A Mostafa, Sandra Campos Mena, Christina Antza, George Balanos et al. • Diabetes & Vascular Disease Research (2022)

Introduction Certain sleep behaviours increase risk of type 2 diabetes mellitus (T2DM) in the general population, but whether they contribute to the progression from pre-diabetes to T2DM is uncertain. We conducted a systematic review to ass...

DOAJ Open Access (DOAJ) DOI: 10.1177/14791641221088824

Brassinosteroid-lipid membrane interaction under low and high temperature stress in model systems

Elżbieta Rudolphi-Szydło, Barbara Dyba, Anna Janeczko, Dariusz Latowski et al. • BMC Plant Biology (2022)

Abstract Background In earlier studies [1], we indicated that applying brassinosteroids (BRs) to lipids that had been isolated from plants altered the physicochemical properties of the monolayers. A continuation of these dependencies using ...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12870-022-03619-4

In vitro effects of European and Latin-American medicinal plants in CYP3A4 gene expression, glutathione levels, and P-glycoprotein activity

Andre Luis Dias Araujo Mazzari, Mariella Guimarães Lacerda, Flora Aparecida Milton, Flora Aparecida Milton et al. • Frontiers in Pharmacology (2022)

Many medicinal plants species from European -such as Artemisia absinthium, Equisetum arvense, Lamium album, Malva sylvestris, Morus nigra, Passiflora incarnata, Frangula purshiana, and Salix alba- as well as Latin American traditions -such ...

DOAJ Open Access (DOAJ) DOI: 10.3389/fphar.2022.826395