Academic Articles & Research Papers

Machine learning models and bankruptcy prediction

Co-optimization of therapeutic antibody affinity and specificity using machine learning models that generalize to novel mutational space

Optimising antibody properties such as affinity can be detrimental to other key properties. Here the authors use machine learning to simplify the identification of antibodies with co-optimal levels of affinity and specificity for a clinical...

Machine learning in chemoinformatics and drug discovery

Chemoinformatics is an established discipline focusing on extracting, processing and extrapolating meaningful data from chemical structures. With the rapid explosion of chemical 'big' data from HTS and combinatorial synthesis, machine learn...

Machine Learning Model Coupled with Graphical User Interface for Predicting Mechanical Properties of Flax Fiber

Machine learning model coupled with graphical user interface was developed to predict mechanical properties of flax fiber. The experiment was conducted using test setup which applies constant rate of loading (CRL). Flax fiber was tested und...

Development of a Data-Based Machine Learning Model for Classifying and Predicting Property Damage Caused by Fire

Large fires in factories cause severe human casualties and property damage. Thus, preparing more economical and efficient management strategies for fire prevention can significantly improve fire safety. This study deals with property damage...

A Protein‐Centric Strategy Coupled with Match‐Between‐Run Glycoproteomics Enables Discovery of Robust Site‐Specific Glycan Biomarkers for Hepatocellular Carcinoma

ABSTRACT Dysregulated protein glycosylation is a hallmark of cancer, and systematic investigation of glycosylation patterns is crucial for identifying biomarkers. However, current glycoproteomic studies are constrained by the limited quanti...

lab2clean: a novel algorithm for automated cleaning of retrospective clinical laboratory results data for secondary uses

Abstract Background The integrity of clinical research and machine learning models in healthcare heavily relies on the quality of underlying clinical laboratory data. However, the preprocessing of this data to ensure its reliability and acc...

Context Aware Evapotranspiration (ETs) for Saline Soils Reclamation

Accurate Evapotranspiration for saline soils (ETs) is important as well as challenging for the reclamation of saline soils through an effective leaching process. Evapotranspiration (ET) by FAO-56 Penman-Monteith standard method is complex, ...

Python Machine Learning

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Optimization for Machine Learning

An up-to-date account of the interplay between optimization and machine learning, accessible to students and researchers in both communities. The interplay between optimization and machine learning is one of the most important developments ...

Machine learning and deep learning

Abstract Today, intelligent systems that offer artificial intelligence capabilities often rely on machine learning. Machine learning describes the capacity of systems to learn from problem-specific training data to automate the process of a...

The voice of depression: speech features as biomarkers for major depressive disorder

Abstract Background Psychiatry faces a challenge due to the lack of objective biomarkers, as current assessments are based on subjective evaluations. Automated speech analysis shows promise in detecting symptom severity in depressed patient...

Machine learning-based diagnostic prediction of minimal change disease: model development study

Abstract Minimal change disease (MCD) is a common cause of nephrotic syndrome. Due to its rapid progression, early detection is essential; however, definitive diagnosis requires invasive kidney biopsy. This study aims to develop non-invasiv...

A feature selection and scoring scheme for dimensionality reduction in a machine learning task

Selection of important features is very vital in machine learning tasks involving high-dimensional dataset with large features. It helps in reducing the dimensionality of a dataset and improving model performance. Most of the feature select...

Selection of target-binding proteins from the information of weakly enriched phage display libraries by deep sequencing and machine learning

Despite the advances in surface-display systems for directed evolution, variants with high affinity are not always enriched due to undesirable biases that increase target-unrelated variants during biopanning. Here, our goal was to design a ...

Predicting Choroidal Nevus Transformation to Melanoma Using Machine Learning

Purpose: To develop and validate machine learning (ML) models to predict choroidal nevus transformation to melanoma based on multimodal imaging at initial presentation. Design: Retrospective multicenter study. Participants: Patients diagnos...

Leveraging Artificial Intelligence to Predict Posterior Malleolus Fracture Extension in Tibial Shaft Fractures

Research Type: Level 3 - Retrospective cohort study, Case-control study, Meta-analysis of Level 3 studies Introduction/Purpose: Occult posterior malleolar fractures (PMFs) are reported commonly in tibial shaft fractures. Presurgical identif...

Assessing climate and land use impacts on surface water yield using remote sensing and machine learning

Abstract Climate and land use changes are critical factors affecting watershed water yields, with significant implications for water resources at both local and regional levels. This study examined the combined effects of temporal and spati...

Machine learning models using longitudinal laboratory data predict survival in allogeneic stem cell recipients.

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