Academic Articles & Research Papers

Evaluating Genomic Testing in Pediatric Inborn Errors of Immunity: An Optimal Model of Care.

Clinical Aspects of Immunology.

Volume 1: anatomical basis of the immune system architecture of immunity induction and regulation of immune responses. Volume 2: advances in technology immunological intervention allergy connective tissue disease immunodeficiency. Volume 3:...

Ultrahypofractionated radiotherapy better preserves B- and T-cell immunity than conventional fractionated radiotherapy in prostate cancer.

The Advances of Single-Cell RNA-Seq in Kidney Immunology

Kidney diseases are highly prevalent and treatment is costly. Immune cells play important roles in kidney diseases; however, it has been challenging to investigate the contribution of each cell type in kidney pathophysiology. Recently, the ...

How <i>Phytophthora</i> Effectors Disrupt Post-Translational Regulation in Plant Immunity: Canonical and Non-Canonical Mechanisms

Plant–pathogen interactions are shaped by dynamic regulatory processes that control immune signaling. Among these, post-translational modifications (PTMs) play central roles in modulating protein activity, stability, and interaction network...

First-Trimester Hematologic Inflammatory Markers and Pregnancy Loss in Women With Unexplained Recurrent Pregnancy Loss: A Retrospective Study of Associations and Discrimination.

Dizziness, Scanning Speech, and Transient Hyperreflexia as Atypical Initial Manifestations of Antiganglioside Q1b-Negative Miller Fisher Syndrome: A Case Report and Literature Review.

ScRNA-Seq Reveals Jiangfu Zhixie Formula Alleviates IBS-D by Inhibiting Macrophage M1 Polarization through HIF-1α-Glycolysis Axis.

Ethnic Differences in Clinical Manifestations of Behçet's Disease: A Retrospective Cohort Study of Turkic and Non-Turkic Patients.

Interacting roles of gut microbiota and T cells in the development of autoimmune hepatitis

Autoimmune hepatitis (AIH) is a progressive liver inflammatory disease mediated by an autoimmune response, with an increasing incidence rate. In severe cases, AIH will rapidly progress to liver cirrhosis and liver failure and even lead to d...

Mechanistic Insights Into How Acupuncture Modulates Host Immunity via the Gut Microbiota-Macrophage Axis.

A Sex-Specific Platelet Switch Controls Anti-Tumor Immunity in Glioblastoma.

Deep learning improves antimicrobial peptide recognition

Motivation: Bacterial resistance to antibiotics is a growing concern. Antimicrobial peptides (AMPs), natural components of innate immunity, are popular targets for developing new drugs. Machine learning methods are now commonly adopted by w...

MalariaSED: a deep learning framework to decipher the regulatory contributions of noncoding variants in malaria parasites

Abstract Malaria remains one of the deadliest infectious diseases. Transcriptional regulation effects of noncoding variants in this unusual genome of malaria parasites remain elusive. We developed a sequence-based, ab initio deep learning f...

Immunogenic cell death-related macrophage gene model for prognostic prediction in glioblastoma

Abstract Glioblastoma (GBM) is an extremely aggressive and diverse type of brain tumor that is associated with a poor prognosis. Immunogenic cell death (ICD) is a particular form of cellular demise that is closely linked to antineoplastic i...

Identification of immune-associated biomarkers of diabetes nephropathy tubulointerstitial injury based on machine learning: a bioinformatics multi-chip integrated analysis

Abstract Background Diabetic nephropathy (DN) is a major microvascular complication of diabetes and has become the leading cause of end-stage renal disease worldwide. A considerable number of DN patients have experienced irreversible end-st...

Knowledge-transfer learning for prediction of matrix metalloprotease substrate-cleavage sites

Abstract Matrix Metalloproteases (MMPs) are an important family of proteases that play crucial roles in key cellular and disease processes. Therefore, MMPs constitute important targets for drug design, development and delivery. Advanced pro...

Apoplast multi-omics profiling during fungal infection uncovers new players of basal and early induced immunity in Arabidopsis thaliana.

Identification and Validation of Hub Genes Associated With Periodontitis and Systemic Lupus Erythematosus.

The Combined Value of the Prognostic Nutritional Index and Pan-Immune-Inflammation Value in Predicting Neoadjuvant Chemotherapy and Survival in Locally Advanced Colon Cancer: A Retrospective Study.