Academic Articles & Research Papers

Neuronal-Derived EV Biomarkers Track Cognitive Decline in Alzheimer’s Disease

The hallmarks of Alzheimer’s disease (AD) pathology are senile plaques containing amyloid-beta (Aβ) and neurofibrillary tangles containing hyperphosphorylated tau. Additional pathologies often co-exist, whereas multiple pathogenic mechanism...

Correlation between frailty and reduction in cortical thickness in patients with chronic obstructive pulmonary disease

Abstract Physical inactivity and cognitive impairment in patients with chronic obstructive pulmonary disease (COPD) can lead to frailty and poor prognoses. However, little is known regarding the association between frailty and the human bra...

Study on Association Between Lipid Profile Values and Psychiatric Disorders

Background: Cholesterol is especially abundant in nervous system, where it plays important role in different aspects of cellular structure (e.g. fluidity of cell membranes) and function (e.g. membrane). Several studies showed that there ...

The Relation between emotional eating and perceived stress among students in tertiary education in Oman: A single-center study

Objectives: Preliminary studies suggested that the high rates of stress are increasingly prevalent in students in tertiary education in the Arabian Gulf countries and that their emotional eating is often triggered by stress. Nevertheless, t...

Correction to: Evaluating a screener to quantify PTSD risk using emergency care information: a proof of concept study

An amendment to this paper has been published and can be accessed via the original article....

Decline in activities of daily living in the rarer dementias

Rarer dementias are associated with atypical symptoms and younger onset, which result in a higher burden of care. We provide a review of the global literature on longitudinal decline in activities of daily living (ADLs) in dementias that ac...

Pilot evaluation of an educational and lived experience training program on ketogenic metabolic therapy in mental health care for health care professionals

BackgroundSerious mental illness imposes a substantial burden. Pharmacologic treatments remain only partially effective and are associated with significant side effects, highlighting the need for novel treatment approaches. Ketogenic metabo...

Personal Recovery in People With a Psychotic Disorder: A Systematic Review and Meta-Analysis of Associated Factors

Background: Personal recovery (PR) is a subjective, multidimensional concept, and quantitative research using PR as an outcome is rapidly increasing. This systematic review is intended to support the design of interventions that contribute ...

Legalisation of non-medical cannabis in Canada: will supply regulations effectively serve public health?

Adolescent victimization and psychosocial well-being in a Finnish population-based sample

ABSTRACTPotentially traumatizing events are common in adolescence, and these experiences have an impact on psychopathology. Furthermore, these events cumulate for certain individuals. More knowledge about the relationship between well-being...

Transcranial direct current stimulation combined with cognitive-behavioral interventions for depressive disorders: a systematic review and meta-analysis of sham-controlled randomized trials

IntroductionDepressive disorders are a prevalent psychiatric condition; major depressive disorder (MDD) specifically affects approximately 5.7% of adults worldwide and is associated with high levels of disability and disease burden. Althoug...

Sex-Related Differences in Regional Homogeneity and Intolerance of Uncertainty in Obsessive-Compulsive Disorder: A Resting-State fMRI Study

Anzhen Wang,1,2 Shuai Zhao,1 Qihui Guo,3,4 Jinling Wu,1 Wenmei Fang,1 Shuang Zheng,1 Chunyan Zhu,2,5,6 Xiangyang Zhang1,3,41Affiliated Psychological Hospital of Anhui Medical University, Anhui Medical University, Hefei, People’s Republic of...

Thematic structure of clinically oriented prefrontal function assessment and intervention research: a keyword network analysis

Abstract Background The prefrontal cortex (PFC) has been extensively investigated in relation to higher-order cognition, emotional regulation, and behavioural control, particularly within clinically oriented studies addressing psychiatric s...

Functional MRI of Handwriting Tasks: A Study of Healthy Young Adults Interacting with a Novel Touch-Sensitive Tablet

Handwriting is a complex human activity that engages a blend of cognitive and visual motor skills. Current understanding of the neural correlates of handwriting has largely come from lesion studies of patients with impaired handwriting. Tas...

Migrant Students’ Sense of Belonging and the Covid‐19 Pandemic: Implications for Educational Inclusion

This article investigates school belonging among migrant students and how this changed during the Covid‐19 pandemic. Drawing on quantitative data gathered from 751 migrant students in secondary schools in six European countries (Belgium, De...

Trait impulsivity prospectively predicts lower methadone treatment retention: moderation by pain catastrophizing

Abstract Background Empirical evidence supports the use of methadone as the standard of care for opioid use disorder. However, low retention in methadone treatment is one of the largest impediments to treatment success. Although several psy...

Context presentation and native conversation structure in large language model responses to escalating suicide risk: a controlled multimodel evaluation

BackgroundLarge language models are increasingly used for informal mental health support, yet their safety during escalating suicide-risk conversations may depend on how prior information is presented. Native multi-turn conversations and re...

Exploring resilience among hospital workers: a Bayesian approach

Background and importanceHealthcare professionals face significant workloads, as their roles are among the most demanding and stressful. Resilience serves as a crucial factor in helping them cope with the challenges encountered in their wor...

A Case Report of Gabapentin-induced Psychotic Disorder

Gabapentin was first approved for treatment of epilepsy by FDA, but later it received more attention due to its effects on pain relief, especially neuropathic pain and post-herpetic neuralgia, and in treatment of anxiety and insomnia. The m...

Why did an effective Dutch complex psycho-social intervention for people with dementia not work in the German healthcare context? Lessons learnt from a process evaluation alongside a multicentre RCT

Background The positive effects of the Dutch Community Occupational Therapy in Dementia programme on patients' daily functioning were not found in a multicentre randomised controlled trial (RCT) in Germany.Objectives To evaluate possible ef...