Academic Articles & Research Papers

Web-based versus simulation-based refresher training in newborn life support

Background: Regular training for healthcare professionals in newborn life support is life-saving. Web-based refresher has the potential to be non-inferior to simulation-based refresher training. Methods: The multicenter non-inferiority rand...

Comparison of the effectiveness of an oral combination of thiamine, pyridoxine, and cyanocobalamin with parenteral cyanocobalamin in adolescents with nutritional vitamin B12 deficiency

Aims: Nutritional vitamin B12 deficiency remains a significant public health issue. This study aimed to compare the efficacy of an oral combination of thiamine, pyridoxine, cyanocobalamin, and parenteral cyanocobalamin treatment among adole...

Medical Informatics and Pediatrics-Reply

We, too, are pleased by the contributions that theArchiveshas made to the medical informatics literature. It is noteworthy that from a historical perspective, the American Journal of Diseases of Children had a reputation for publishing land...

Early Retinal Microvascular Alterations in Young Type 1 Diabetic Patients without Clinical Retinopathy

The purpose of this study is to identify and quantify preclinical changes with the help of optical coherence tomography angiography (OCTA) within the retinal microcirculation of young type 1 diabetes (T1D) patients without clinical signs of...

Brain perfusion imaging in neonates

Abnormal variations of the neonatal brain perfusion can result in long-term neurodevelopmental consequences and cerebral perfusion imaging can play an important role in diagnostic and therapeutic decision-making. To identify at-risk situati...

Medical Informatics and Pediatrics

Decision support is an important area of medical informatics research. Computer-based decision-support tools facilitate diagnosis and the management of patients after a diagnosis has been established. Diagnostic decision-support tools, such...

Medical Informatics and Pediatrics

We were very pleased to see the article Medical Informatics and Pediatrics: Decision-Support System in the December 1995 issue. 1 TheArchivesis taking the lead in providing a series of academic articles on informatics topics for the pediatr...

MEDICAL INFORMATICS

Medical informatics, according to two US researchers, "is emerging as a distinct academic entity." More cynically one could say that the academic world has realised that grants are to be had, jobs created, and money made from building datab...

Sex-specific frontal-striatal connectivity differences among adolescents with externalizing disorders

Background: Sex-specific neurobiological underpinnings of impulsivity in youth with externalizing disorders have not been well studied. The only report of functional connectivity (FC) findings in this area demonstrated sex differences in fr...

Publisher Correction: Endophenotype effect sizes support variant pathogenicity in monogenic disease susceptibility genes

Prenatal to postnatal trajectory of brain growth in complex congenital heart disease

Altered brain development is a common feature of the neurological sequelae of complex congenital heart disease (CHD). These alterations include abnormalities in brain size and growth that begin prenatally and persist postnatally. However, t...

¿Cómo es la cirugía cardiaca neonatal en un centro terciario en México?

Resumen: Introducción y objetivos: México posee instituciones públicas y privadas para atender a 120 millones de habitantes. Nuestro hospital pediátrico es una institución pública del Instituto Mexicano del Seguro Social. Presentamos nuest...

Assessing the health impacts of parenthood on people with cystic fibrosis: the HOPeCF prospective cohort protocol

Introduction People with cystic fibrosis (CF) are living longer and healthier lives with a growing number considering and pursuing parenthood. The decision of whether to become a parent is complex for people with CF, and CF is a major facto...

Antibody response after pneumococcal vaccination in a large cohort of Italian children and adolescents with Down syndrome

Introduction: Pneumococcal vaccination has significantly decreased the burden of invasive pneumococcal disease in the general population, however studies on effectiveness in Down syndrome (DS) are heterogeneous. In this cross-sectional stud...

Allele-specific polymerase chain reaction can determine the diplotype of NUDT15 variants in patients with childhood acute lymphoblastic Leukemia

Abstract Mercaptopurine intolerance is an adverse effect of mercaptopurine administration in pediatric patients with acute lymphoblastic leukemia (ALL). NUDT15 variants have emerged as major determinants of mercaptopurine intolerance, espec...

Virulence Genes Profile of Multidrug Resistant Pseudomonas aeruginosa Isolated from Iranian Children with UTIs

Virulent and resistant strains Pseudomonas aeruginosa (P. aeruginosa) is one of the most important cause of UTIs in pediatrics. The present study was carried to investigate the frequency of virulence factors in the multi-drug resistant stra...

PRODUCTION OF L-TRYPTOPHAN BY MUTANTS OF CORYNEBACTERIUM GLUTAMICUM

L-Tryptophan, is one of the amino acids, also is one of the 9 essential amino acids of human which cannot be synthesized internally by him, microbial production is the main method for obtaining tryptophan for commercial uses. Typical microo...

Digital Transition and Mental Health in School Settings: Does Handwriting Still Matter? A Multidisciplinary Perspective

Background/Objectives: The digital transition in school settings is reshaping children’s learning, writing practices, and mental health trajectories. This narrative review examines whether handwriting still matters in contemporary hybrid ed...

Continuous positive airway pressure for children with undifferentiated respiratory distress in Ghana: an open-label, cluster, crossover trial

Background: In low-income and middle-income countries, invasive mechanical ventilation is often not available for children at risk of death from respiratory failure. We aimed to determine if continuous positive airway pressure (CPAP), a for...

Knowledge, attitude, and practices of pediatricians about children’s oral health

BACKGROUND: Many pediatric oral diseases are preventable if physicians recognize and encourage preventive care and refer patients to dentists whenever necessary. Parents usually visit pediatricians for routine care during the first few year...