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Academic Articles & Research Papers
Showing 20 of 192 academic articles
Linping Hui, Siyang Zhang, Muli Wudu, Hongjiu Ren et al. • Thoracic Cancer
(2019)
Background Studies have shown that E3 ubiquitin ligase CBLL1 plays multiple roles in development and tumorigenesis. CBLL1 is over‐expressed in colon cancer and associated with cancer cell proliferation. While, the overexpression of CBLL1 in...
DOAJ
Open Access (DOAJ)
DOI: 10.1111/1759-7714.13097
Yuxiong Lu, Junichi Maruyama, Keiko Kuwata, Hiroyuki Fukuda et al. • Biochemistry and Biophysics Reports
(2018)
Doublecortin-like kinase 1 (DCLK1) is a serine/threonine-kinase with two doublecortin (DCX) domains. DCLK1 is associated with microtubules via DCX domains and regulates microtubule polymerization. DCLK1 is known to be expressed in cancer st...
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Open Access (DOAJ)
DOI: 10.1016/j.bbrep.2018.10.014
Lucas Rodrigues Moraes, Pedro Leme Silva, Denise Battaglini, Patricia Rieken Macedo Rocco • Medicina
(2026)
Acute respiratory distress syndrome (ARDS) is a heterogeneous inflammatory lung injury marked by increased alveolar–capillary permeability, reduced respiratory system compliance, and impaired gas exchange. Despite advances in supportive car...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/medicina62020420
Hoda Zarkoob, Anna Allué-Guardia, Yu-Chi Chen, Andreu Garcia-Vilanova et al. • Communications Biology
(2022)
Human alveolar and tracheobronchial epithelial air liquid interface (ALI) tissues are used as models to examine cellular responses to SARS-CoV-2 and influenza A virus infections and as antiviral drug screening assay platforms....
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Open Access (DOAJ)
DOI: 10.1038/s42003-022-03753-7
Saul Vislei Simões da Silva, Orlando Maia Barboza, Jéssica Teles Souza, Érica Novaes Soares et al. • Molecules
(2021)
Quercetin (Q) is a bioflavonoid with biological potential; however, poor solubility in water, extensive enzymatic metabolism and a reduced bioavailability limit its biopharmacological use. The aim of this study was to perform structural mod...
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Open Access (DOAJ)
DOI: 10.3390/molecules26226923
Yan Dora Zhang, Amber N. Hurson, Haoyu Zhang, Parichoy Pal Choudhury et al. • Nature Communications
(2020)
In cancer many gene variants may contribute to disease etiology, but the impact of a given gene variant may have varied effect size. Here, the authors analyse summary statistics of genome-wide association studies from fourteen cancers, and ...
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Open Access (DOAJ)
DOI: 10.1038/s41467-020-16483-3
Olivia Brabant, Yuliya V. Karpievitch, Yuliya V. Karpievitch, Alphons Gwatimba et al. • Frontiers in Veterinary Science
(2024)
Respiratory disease in cattle is a significant global concern, yet current diagnostic methods are limited, and there is a lack of crush-side tests for detecting active disease. To address this gap, we propose utilizing electrical impedance ...
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Open Access (DOAJ)
DOI: 10.3389/fvets.2023.1275013
Luyao Hao, Luyao Hao, Fengmiao Zhao, Fengmiao Zhao et al. • Frontiers in Veterinary Science
(2025)
In recent years, bovine viral diarrhea virus (BVDV) has been associated with increased respiratory and gastrointestinal diseases in cattle. Comprehensive monitoring and investigations into the virus's pathological features are crucial for d...
DOAJ
Open Access (DOAJ)
DOI: 10.3389/fvets.2025.1554986
Wei Liao, PhD, Meredith Ray, PhD, Carrie Fehnel, BBA, Jordan Goss, MA et al. • JTO Clinical and Research Reports
(2024)
Introduction: Low-dose computed tomography screening (LDCT) and lung nodule programs (LNP) promote early lung cancer detection, improve survival; Multidisciplinary Care Programs (MDC) promote guideline-concordant care. The impact of such pr...
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Open Access (DOAJ)
DOI: 10.1016/j.jtocrr.2023.100629
Rebecca Black, BApSc, Speech Pathologist(SP), Duy Duong Nguyen, MD PhD, Anna Miles, PhD, Daniel Novakovic, MBBS, FRACS, MPH et al. • JHLT Open
(2025)
Background: Oropharyngeal dysphagia and laryngeal dysfunction are complications of lung and heart transplantation. However, there is a lack of understanding around pre-operative function and an absence of standardized assessment protocols. ...
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Open Access (DOAJ)
DOI: 10.1016/j.jhlto.2025.100261
Lingling Tang, Jinjin Liu, Linyun Zhu, Qingge Chen et al. • Frontiers in Pharmacology
(2018)
Lung squamous cell carcinoma (LSCC) is a common histological lung cancer subtype, but unlike lung adenocarcinoma, limited therapeutic options are available for treatment. Curcumin, a natural compound, may have anticancer effects in various ...
DOAJ
Open Access (DOAJ)
DOI: 10.3389/fphar.2018.00060
Bongani Sannyboy Lukhele, Kokoette Bassey, Bwalya Angel Witika • Current Issues in Molecular Biology
(2023)
Medicinal plants have been utilized to treat a variety of conditions on account of the bioactive properties that they contain. Most bioactive constituents from plants are of limited effectiveness, due to poor solubility, limited permeabilit...
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Open Access (DOAJ)
DOI: 10.3390/cimb45120624
Elena Alexander, Kam W. Leong • Frontiers in Nanotechnology
(2025)
IntroductionNanomaterials are extensively utilized in applications ranging from electronics to biomedical therapies; however, their widespread use has prompted concerns about potential toxicity in humans. Understanding the biodistribution a...
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Open Access (DOAJ)
DOI: 10.3389/fnano.2025.1512622
Matthew Lynch, Sophie Manoy, Peter D. Sly, Claire E. Wainwright et al. • EBioMedicine
(2025)
Summary: Background: Ataxia-telangiectasia (A-T) is a rare multisystem disease characterised by neurodegenerative cerebellar ataxia, lung disease, immune deficiency, high cancer risk, and mitochondrial dysfunction. A-T cells demonstrate de...
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Open Access (DOAJ)
DOI: 10.1016/j.ebiom.2025.105840
Heabin Kim, Hyun-Taek Kim, Seung-Hyun Jung, Jong Won Han et al. • Marine Drugs
(2023)
The discovery of new highly effective anticancer drugs with few side effects is a challenge for drug development research. Natural or synthetic anticancer peptides (ACPs) represent a new generation of anticancer agents with high selectivity...
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Open Access (DOAJ)
DOI: 10.3390/md21120607
M. S. Clark, J. I. Hoffman, L. S. Peck, L. Bargelloni et al. • Nature Communications
(2023)
Abstract Polar ecosystems are experiencing amongst the most rapid rates of regional warming on Earth. Here, we discuss ‘omics’ approaches to investigate polar biodiversity, including the current state of the art, future perspectives and rec...
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Open Access (DOAJ)
DOI: 10.1038/s41467-023-43209-y
H. Mathys • Geographica Helvetica
No abstract available....
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Open Access (DOAJ)
DOI: 10.5194/gh-39-80-1984
Lilla Bűdi, Dániel Hammer, Rita Varga, Veronika Müller et al. • Pathology and Oncology Research
(2025)
ObjectivesSpingosine-1-phosphate (S1P) and ceramides are bioactive sphingolipids that influence cancer cell fate. Anti-ceramide antibodies might inhibit the effects of ceramide. The aim of this study was to assess the potential role of circ...
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Open Access (DOAJ)
DOI: 10.3389/pore.2024.1611929
Sarah Damanti, Francesca Rosini, Daniela Mari, Maura Marcucci • European Journal of Case Reports in Internal Medicine
(2015)
We report a case of acute facial oedema in an elderly hospitalized patient which was initially misdiagnosed as angioedema secondary to antibiotics in a patient with an allergic diathesis.
We describe the differential aetiologies and then t...
DOAJ
Open Access (DOAJ)
DOI: 10.12890/2015_000281
Eva Steinke, Eva Steinke, Eva Steinke, Olaf Sommerburg et al. • Frontiers in Medicine
(2023)
BackgroundLung disease as major cause for morbidity in patients with cystic fibrosis (CF) starts early in life. Its large phenotypic heterogeneity is partially explained by the genotype but other contributing factors are not well delineated...
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Open Access (DOAJ)
DOI: 10.3389/fmed.2022.1034290