Reset
Showing 20 of 134 academic articles

Bone Diagenesis in Short Timescales: Insights from an Exploratory Proteomic Analysis

Noemi Procopio, Caley A. Mein, Sefora Starace, Andrea Bonicelli et al. • Biology (2021)

The evaluation of bone diagenetic phenomena in archaeological timescales has a long history; however, little is known about the origins of the microbes driving bone diagenesis, nor about the extent of bone diagenesis in short timeframes—suc...

DOAJ Open Access (DOAJ) DOI: 10.3390/biology10060460

miR-3113-5p, miR-223-3p, miR-133a-3p, and miR-499a-5p are sensitive biomarkers to diagnose sudden cardiac death

Fengping Yan, Yuanyuan Chen, Xing Ye, Fu Zhang et al. • Diagnostic Pathology (2021)

Abstract Background Sudden cardiac death (SCD) remains a great health threat and diagnostic challenge, especially those cases without positive autopsy findings. Molecular biomarkers have been urgently needed for the diagnosis of SCD display...

DOAJ Open Access (DOAJ) DOI: 10.1186/s13000-021-01127-x

UPLC-MS/MS Metabolomics Reveals Babao Dan’s Mechanisms in MASH Treatment with Integrating Network Pharmacology and Molecular Docking

Shijiao Zhang, Yanding Su, Ao Han, He Qi et al. • Pharmaceuticals (2025)

Background: Metabolic dysfunction-associated steatohepatitis (MASH) is a progressive disease that easily develops into cirrhosis and hepatocellular carcinoma, but its pathogenesis is not clear, and most therapeutic drugs have obvious limita...

DOAJ Open Access (DOAJ) DOI: 10.3390/ph18081111

Impact of <i>Chlorella vulgaris</i> Bioremediation and Selenium on Genotoxicity, Nephrotoxicity and Oxidative/Antioxidant Imbalance Induced by Polystyrene Nanoplastics in African Catfish (<i>Clarias gariepinus</i>)

Shimaa A. Abdelbaky, Zakaria M. Zaky, Doha Yahia, Mohamed H. Kotob et al. • Fishes (2024)

Contamination of the environment with nano- and microplastic particles exerts a threatening impact on the aquatic ecosystems and sustainable catfish aquaculture. The presence of nanoplastics has been found to have a detrimental impact on bo...

DOAJ Open Access (DOAJ) DOI: 10.3390/fishes9020076

Anti-inflammatory activity of two varieties of pumpkin seed oil in an adjuvant arthritis model in rats

S. Y. Al-Okbi, D. A. Mohamed, E. Kandil, M. A. Abo-Zeid et al. • Grasas y Aceites (2017)

The aim of the present research was to evaluate the anti-inflammatory activity of pumpkin seed oils (PSOs) of an Egyptian and European variety, in a rat model of adjuvant arthritis. Edema thickness, plasma tumor necrosis factor-α (TNF-α) an...

DOAJ Open Access (DOAJ) DOI: 10.3989/gya.0796161

TRACK-CF prospective cohort study: Understanding early cystic fibrosis lung disease

Eva Steinke, Eva Steinke, Eva Steinke, Olaf Sommerburg et al. • Frontiers in Medicine (2023)

BackgroundLung disease as major cause for morbidity in patients with cystic fibrosis (CF) starts early in life. Its large phenotypic heterogeneity is partially explained by the genotype but other contributing factors are not well delineated...

DOAJ Open Access (DOAJ) DOI: 10.3389/fmed.2022.1034290

Exploring the Intestinal Microbiota and Metabolome Profiles Associated With Feed Efficiency in Pacific Abalone (Haliotis discus hannai)

Wenchao Yu, Wenchao Yu, Yisha Lu, Yisha Lu et al. • Frontiers in Microbiology (2022)

Feed efficiency (FE) is critical to the economic and environmental benefits of aquaculture. Both the intestines and intestinal microbiota play a key role in energy acquisition and influence FE. In the current research, intestinal microbiota...

DOAJ Open Access (DOAJ) DOI: 10.3389/fmicb.2022.852460

Digital health technologies and major depressive disorder

Roger S. McIntyre, Walter Greenleaf, Grzegorz W. Bulaj, Steven T. Taylor et al. • CNS Spectrums (2023)

There is an urgent need to improve the clinical management of major depressive disorder (MDD), which has become increasingly prevalent over the past two decades. Several gaps and challenges in the awareness, detection, treatment, and monito...

OPENALEX cc-by-nc DOI: https://doi.org/10.1017/s1092852923002225

Digital biomarkers: Convergence of digital health technologies and biomarkers

Srikanth Vasudevan, Anindita Saha, Michelle E. Tarver, Bakul Patel • npj Digital Medicine (2022)

Over the last decade, increasing digitization across the healthcare continuum has revolutionized medical research, diagnostics, and therapeutics. This digitization has led to rapid advancements in the development and adoption of digital hea...

OPENALEX cc-by DOI: https://doi.org/10.1038/s41746-022-00583-z PMC: 8956713

Predictive Value of Serum Cytokeratin 19 Level for the Feasibility of Conserving Ovaries in Endometrial Cancer

Jie Xu, Jie Xu, Can Chen, Can Chen et al. • Frontiers in Medicine (2021)

Objective: To determine the predictive value of cytokeratin 19 (CK19) for evaluating the safety of ovarian preservation in patients with endometrial cancer (EC).Methods: Five hundred and seventeen EC patients hospitalized from November 2010...

DOAJ Open Access (DOAJ) DOI: 10.3389/fmed.2021.670109

Plasma Non-Enzymatic Antioxidant Capacity (NEAC) in Relation to Dietary NEAC, Nutrient Antioxidants and Inflammation-Related Biomarkers

Cayetano Javier Carrión-García, Eduardo Jesús Guerra-Hernández, Belén García-Villanova, Mauro Serafini et al. • Antioxidants (2020)

(1) Background: Little is known about the interlinkages between dietary and plasma non-enzymatic antioxidant capacity (D-NEAC and P-NEAC, respectively) and the body’s antioxidant and inflammation response. Our aim was to explore these assoc...

DOAJ Open Access (DOAJ) DOI: 10.3390/antiox9040301

Mapping the acute trajectory of sport-related concussion outcomes across symptoms, cognition, and blood biomarkers

SoYoung Ahn, Michael Prock, Ji-won Seo, Sanghyuk Han et al. • Sports Medicine and Health Science (2026)

Sport-related concussion (SRC) and its potential neurological sequela represent an emerging global health concern, requiring improved recovery management and strategies for return-to-play (RTP) to enhance brain health in athletes. Given the...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.smhs.2025.07.003

Advances in High Throughput Proteomics Profiling in Establishing Potential Biomarkers for Gastrointestinal Cancer

Md Zahirul Islam Khan, Shing Yau Tam, Helen Ka Wai Law • Cells (2022)

Gastrointestinal cancers (GICs) remain the most diagnosed cancers and accounted for the highest cancer-related death globally. The prognosis and treatment outcomes of many GICs are poor because most of the cases are diagnosed in advanced me...

DOAJ Open Access (DOAJ) DOI: 10.3390/cells11060973

Oh brother, where art tau? Amyloid, neurodegeneration, and cognitive decline without elevated tau

Lauren E. McCollum, Sandhitsu R. Das, Long Xie, Robin de Flores et al. • NeuroImage: Clinical (2021)

Mild cognitive impairment (MCI) can be an early manifestation of Alzheimer’s disease (AD) pathology, other pathologic entities [e.g., cerebrovascular disease, Lewy body disease, LATE (limbic-predominant age-related TDP-43 encephalopathy)], ...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.nicl.2021.102717

Early Retinal Microvascular Alterations in Young Type 1 Diabetic Patients without Clinical Retinopathy

Alexandra Oltea Dan, Alin Ștefănescu-Dima, Andrei Teodor Bălășoiu, Ileana Puiu et al. • Diagnostics (2023)

The purpose of this study is to identify and quantify preclinical changes with the help of optical coherence tomography angiography (OCTA) within the retinal microcirculation of young type 1 diabetes (T1D) patients without clinical signs of...

DOAJ Open Access (DOAJ) DOI: 10.3390/diagnostics13091648

From Connectivity to Controllability: Unraveling the Brain Biomarkers of Major Depressive Disorder

Chunyu Pan, Ying Ma, Lifei Wang, Yan Zhang et al. • Brain Sciences (2024)

Major Depressive Disorder (MDD) is a significant neurological condition associated with aberrations in brain functional networks. Traditional studies have predominantly analyzed these from a network topology perspective. However, given the ...

DOAJ Open Access (DOAJ) DOI: 10.3390/brainsci14050509

Grey matter volume associations with personality functioning in a clinical cohort of female youths

Madelyn Thomson, Marialuisa Cavelti, Ines Mürner-Lavanchy, Silvano Sele et al. • NeuroImage: Clinical (2026)

Borderline Personality Disorder (BPD) is a severe mental illness, although its neurobiological underpinnings remain largely unknown. Structural Magnetic Resonance Imaging (sMRI) in adolescents can offer insights into potential biomarkers to...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.nicl.2026.103988

Computational Tools; Indispensable Armamentarium of Medical Biotechnology

Nutan, Swapnil Jain, K Shilpa, Akanksha Tomar et al. • Indian Journal of Science and Technology (2016)

Objective: Computational infrastructure of medical biotechnology provides insight into elements of genomics, proteomics for understanding diseases and biological systems in a more comprehensive and systematic way. The present study exclusiv...

OPENALEX cc-by DOI: https://doi.org/10.17485/ijst/2016/v9i32/100745

SIRT1 and miR-34a as Potential Plasma Biomarkers in the Acute Phase of Ischemic Stroke

Mitra Ansari, Moslem Esmati, Seyed khalil Rashidi, Shahram Rafie et al. • International Journal of Molecular and Cellular Medicine (2025)

Stroke is the major cause of disability and mortality worldwide. Identification of molecular biomarkers in the early hours after stroke is important in terms of both diagnostic and therapeutic applications. miR-34a, a highly expressed miRNA...

DOAJ Open Access (DOAJ)

International Journal of Medical Biotechnology & Genetics

Saket RD, Kol S, Tripathi AK, Singh SP et al. • International Journal of Medical Biotechnology & Genetics (2022)

International Journal of Medical Biotechnology & Genetics (IJMBG) ISSN: 2379-1020 is a comprehensive, peer reviewed journal devoted to Medical Biotechnology and Genetics. publishes original research, latest developments, review papers, scie...

OPENALEX cc-by DOI: https://doi.org/10.19070/2379-1020