Academic Articles & Research Papers

The development of health technology assessment in Brazil

OBJECTIVES: The aim of this study was to describe the developing health technology assessment (HTA) activities in Brazil, both historically and in the present day. METHODS: This report is a descriptive analysis based on personal experiences...

Association between Higher Blood Pressure and Risk of Diabetes Mellitus in Middle-Aged and Elderly Chinese Adults

BackgroundTo examine the prospective association between higher blood pressure (BP) and risk of type 2 diabetes mellitus (T2DM) in middle-aged and elderly Chinese adults.MethodsA total of 9,642 middle-aged and elderly Chinese adults (≥45 ye...

Semi-enclosed experimental system for coal spontaneous combustion for determining regional distribution of high-temperature zone of coal fire

Abstract Temperature variation and gas generation at different depths and positions in the coal combustion process were studied to determine the propagation and evolution of high temperature regions in the process of coal spontaneous combus...

Healthy lifestyle attenuates the clonal hematopoiesis-associated coronary artery disease risk

Lifestyle factors and clonal hematopoiesis of indeterminate potential (CHIP) both contribute to the risk of developing coronary artery disease (CAD), but whether a healthy lifestyle could attenuate CHIP-related CAD risk is unknown. A total ...

Spatiotemporal analysis of hospitalizations, mortality and access to intravenous thrombolysis for ischemic stroke in Southern Brazil

Abstract Background Globally, stroke is a leading cause of mortality and disability, affecting approximately 15 million people annually. This study aimed to analyze hospitalizations, deaths, and thrombolysis for ischemic stroke in Southern ...

Digital health technology and diabetes management

Diabetes care is largely dependent on patient self-management and empowerment, given that patients with diabetes must make numerous daily decisions as to what to eat, when to exercise, and determine their insulin dose and timing if required...

Pathway analysis of the impact of family function and self-efficacy on depression and anxiety in patients undergoing in vitro fertilization-embryo transfer

Abstract Background Patients undergoing assisted reproductive technology (ART) experience significant psychological distress due to infertility, with depression and anxiety being the most common manifestations. This study investigates the i...

Research on older people's health information search behavior based on risk perception in social networks—A case study in China during COVID-19

ObjectiveCOVID-19 has caused great loss of human life and livelihoods. The dissemination of health information in online social networks increased during the pandemic's quarantine. Older people are the most vulnerable group in sudden public...

Health Technology Assessment

Multimodal Physical Therapy Management of Dysmenorrhea With Coexisting Mechanical Low Back Pain and Early Degenerative Lumbar Spondylosis: A Case Report

ABSTRACT A 21‐year‐old woman with dysmenorrhea, mechanical low back pain, early lumbar spondylosis, heavy menstrual bleeding, and anemia received 4 weeks of multimodal physiotherapy. Pain and function improved, but heavy bleeding created di...

European network for Health Technology Assessment, EUnetHTA: Planning, development, and implementation of a sustainable European network for Health Technology Assessment

OBJECTIVES: The European network on Health Technology Assessment (EUnetHTA) aimed to produce tangible and practical results to be used in the various phases of health technology assessment and to establish a framework and processes to suppo...

LADS: a powerful vaccine platform for cancer immunotherapy and prevention

Abstract Background The intracellular bacterium Listeria monocytogenes is an attractive vector for cancer immunotherapy as it can effectively deliver tumor antigens to antigen-presenting cells, leading to a robust antitumor response. Result...

Design and Optimization of Trastuzumab-Functionalized Nanolipid Carriers for Targeted Capecitabine Delivery: Anti-Cancer Effectiveness Evaluation in MCF-7 and SKBR3 Cells

Shubhashree Das,1 Bhabani Sankar Satapathy,2 Gurudutta Pattnaik,1 Sovan Pattanaik,3 Yahya Alhamhoom,4 Mohamed Rahamathulla,4 Mohammed Muqtader Ahmed,5 Ismail Pasha6 1Department of Pharmaceutics, School of Pharmacy and Life Sciences, Centuri...

Cross-national validation of the MHQoL: psychometric evaluation and open-source tools for assessing mental health quality of life

Objectives To validate the cross-national psychometric properties of the Mental Health Quality of Life questionnaire (MHQoL) and to develop an open-source toolbox for its scoring, transformation and presentation.Design Secondary analysis of...

Improving Diabetes Management With Mobile Health Technology

Mapping the acute trajectory of sport-related concussion outcomes across symptoms, cognition, and blood biomarkers

Sport-related concussion (SRC) and its potential neurological sequela represent an emerging global health concern, requiring improved recovery management and strategies for return-to-play (RTP) to enhance brain health in athletes. Given the...

Health technology assessment in Canada

Canada's health system is a unique combination of public financing and private provision. With the significant government role in financing health services, health technology assessment (HTA) has found a ready audience as a form of policy r...

Serum amyloid beta 42 levels correlated with metabolic syndrome and its components

IntroductionBeta-amyloid accumulation in the brain appears to be a key initiating event in Alzheimer’s disease (AD), and factors associated with increased deposition of beta-amyloid are of great interest. Enhanced deposition of amyloid-β pe...

Change in lifestyle with health technology

To preserve excellent health and prevent chronic diseases, one must adopt a healthy lifestyle. Yet, altering one's way of life can be difficult, particularly without the necessary resources and assistance. Luckily, new opportunities to enco...

Development of health technology assessment

Health technology refers to the special knowledge used in health care and medical services and health technology assessment is to assess the efficacy, safety, economics and social consequences of health technology. Under the coordination of...