Academic Articles & Research Papers

Epigenetic Mechanisms and Nephrotic Syndrome: A Systematic Review

A small subset of people with nephrotic syndrome (NS) have genetically driven disease. However, the disease mechanisms for the remaining majority are unknown. Epigenetic marks are reversible but stable regulators of gene expression with uti...

EFFICACY AND SAFETY OF INCLISIRAN BY BASELINE BODY MASS INDEX: A POST HOC POOLED ANALYSIS OF THE ORION-9, ORION-10 AND ORION-11 PHASE III RANDOMIZED CONTROLLED TRIALS

Therapeutic Area: ASCVD/CVD Risk Factors Background: Excessive bodyweight, often associated with dyslipidemia, may affect the pharmacology of drugs. Inclisiran, a small interfering RNA targeting PCSK9 hepatic mRNA, is an effective LDL-C low...

A Dictionary of Epidemiology.

Nurse-coordinated home-based cardiac rehabilitation for patients with heart failure: A scoping review

Objectives: This study aimed to review and summarize the studies of nurse-coordinated home-based cardiac rehabilitation for patients with heart failure. Methods: The review was performed using Arksey and O’Malley’s scoping review framework....

Nanoparticles: Taking a Unique Position in Medicine

The human nature of curiosity, wonder, and ingenuity date back to the age of humankind. In parallel with our history of civilization, interest in scientific approaches to unravel mechanisms underlying natural phenomena has been developing. ...

Herbal Medicines in African Traditional Medicine

African traditional medicine is a form of holistic health care system organized into three levels of specialty, namely divination, spiritualism, and herbalism. The traditional healer provides health care services based on culture, religious...

A novel sensor-based assessment of lower limb spasticity in children with cerebral palsy

Abstract Background To provide effective interventions for spasticity, accurate and reliable spasticity assessment is essential. For the assessment, the Modified Tardieu Scale (MTS) has been widely used owing to its simplicity and convenien...

A Deep Learning Harmonization of Multi-Vendor MRI for Robust Intervertebral Disc Segmentation

Magnetic resonance imaging (MRI) provides enhanced soft tissue contrast and high spatial resolution. However, the relationship between intensity values among soft tissues in MRI is inconsistent, even when obtained under the same conditions ...

Acoustic Cell Patterning for Structured Cell‐Laden Hydrogel Fibers/Tubules

Abstract Cell‐laden hydrogel fibers/tubules are one of the fundamentals of tissue engineering. They have been proven as a promising method for constructing biomimetic tissues, such as muscle fibers, nerve conduits, tendon and vessels, etc. ...

Stochastic brain dynamics exhibits differential regional distribution and maturation-related changes

Functional magnetic resonance imaging (fMRI) is a powerful non-invasive method for studying brain function by analyzing blood oxygenation level-dependent (BOLD) signals. These signals arise from intricate interplays of deterministic and sto...

Functional Fibers and Fabrics for Soft Robotics, Wearables, and Human–Robot Interface

Soft robotics inspired by the movement of living organisms, with excellent adaptability and accuracy for accomplishing tasks, are highly desirable for efficient operations and safe interactions with human. With the emerging wearable electro...

A Vision-Based Approach for Estimating Contact Forces: Applications to Robot-Assisted Surgery

The primary goal of this paper is to provide force feedback to the user using vision-based techniques. The approach presented in this paper can be used to provide force feedback to the surgeon for robot-assisted procedures. As proof of conc...

Characterization of Wing Kinematics by Decoupling Joint Movement in the Pigeon

Birds have remarkable flight capabilities due to their adaptive wing morphology. However, studying live birds is time-consuming and laborious, and obtaining information about the complete wingbeat cycle is difficult. To address this issue a...

Effects of gait support in patients with spinocerebellar degeneration by a wearable robot based on synchronization control

Abstract Background Spinocerebellar degeneration (SCD) mainly manifests a cerebellar ataxic gait, leading to marked postural sway and the risk of falling down. Gait support using a wearable robot is expected to be an effective solution to m...

Design and modelling of an anisotropic continuum robot end-effector for single-port access surgery suturing

Single port access surgery has brought many advantages and new challenges to the field of minimally invasive surgery. In principle, many of these challenges can be addressed through robotics. Continuum robots in particular have seen a surge...

Two decades of breakthroughs: charting the future of NeuroEngineering and Rehabilitation

Abstract The Journal of NeuroEngineering and Rehabilitation (JNER) has become a major actor for the dissemination of knowledge in the scientific community, bridging the gaps between innovative neuroengineering and rehabilitation. Major fiel...

Boosting precision crop protection towards agriculture 5.0 via machine learning and emerging technologies: A contextual review

Crop protection is a key activity for the sustainability and feasibility of agriculture in a current context of climate change, which is causing the destabilization of agricultural practices and an increase in the incidence of current or in...

Remodeling of Endothelial Cell Nucleus Exposed to Three Different Mechanical Stimuli

Cell Nuclei play a critical role in controlling gene expression and replicating DNA, and is known to deform in association with cell shape changes in response to external forces. This study dealed with morphological analysis to quantitative...

Fundamentals and Advances in Stimuli-Responsive Hydrogels and Their Applications: A Review

This review summarizes the fundamental concepts, recent advancements, and emerging trends in the field of stimuli-responsive hydrogels. While numerous reviews exist on this topic, the field continues to evolve dynamically, and certain resea...

Soft Robotics: New Perspectives for Robot Bodyware and Control

The remarkable advances of robotics in the last 50 years, which represent an incredible wealth of knowledge, are based on the fundamental assumption that robots are chains of rigid links. The use of soft materials in robotics, driven not on...