Academic Articles & Research Papers

A Protein‐Centric Strategy Coupled with Match‐Between‐Run Glycoproteomics Enables Discovery of Robust Site‐Specific Glycan Biomarkers for Hepatocellular Carcinoma

ABSTRACT Dysregulated protein glycosylation is a hallmark of cancer, and systematic investigation of glycosylation patterns is crucial for identifying biomarkers. However, current glycoproteomic studies are constrained by the limited quanti...

Towards instance-wise calibration: local amortized diagnostics and reshaping of conditional densities (LADaR)

Key science questions, such as galaxy distance estimation and weather forecasting, often require knowing the full predictive distribution of a target variable Y given complex inputs X . Despite recent advances in machine learning and physic...

Bioinformatics the machine learning approach

In this book Pierre Baldi and Soren Brunak present the key machine learning approaches and apply them to the computational problems encountered in the analysis of biological data. The book is aimed both at biologists and biochemists who nee...

Machine learning phases of matter

Machine learning and the physical sciences

In October 2018 an APS Physics Next Workshop on Machine Learning was held in Riverhead, NY. This article reviews and summarizes the proceedings of this very broad, emerging field.This needs to be a placard in the left-hand column, with a cu...

Inferring Markovian quantum master equations of few-body observables in interacting spin chains

Full information about a many-body quantum system is usually out-of-reach due to the exponential growth—with the size of the system—of the number of parameters needed to encode its state. Nonetheless, in order to understand the complex phen...

Artificial intelligence

This chapter explores the extensive potential of artificial intelligence (AI), which has been recognized and harnessed by computer scientists, including physics and life sciences. It analyses how AI is applied to those areas of chemistry th...

An information theoretic limit to data amplification

In recent years generative artificial intelligence has been used to create data to support scientific analysis. For example, generative adversarial networks (GANs) have been trained using Monte Carlo simulated input and then used to generat...

Artificial intelligence

In a departure from usual practice, the Science Research Council has published a 'paper symposium' on artificial intelligence (AI), to stimulate discussion within the British science community before making a decision on the extent and allo...

Evidence for Dynamical Filtering: High Binary Fraction, Hard-binary Excess, and Unresolved Triples in the Surviving Core of NGC 6791

We present a deep photometric analysis of the main-sequence (MS) population in the old, metal-rich open cluster (OC) NGC 6791 using Gaia Data Release 3 data. After correcting for differential reddening, we use the Bayesian model comparison ...

Artificial intelligence: A powerful paradigm for scientific research

Artificial intelligence (AI) coupled with promising machine learning (ML) techniques well known from computer science is broadly affecting many aspects of various fields including science and technology, industry, and even our day-to-day li...

A Generative Super‐Resolution Model for Enhancing Tropical Cyclone Wind Field Intensity and Resolution

Abstract Extreme winds associated with tropical cyclones (TCs) can cause significant loss of life and economic damage globally, highlighting the need for accurate, high‐resolution modeling and forecasting for wind. However, due to their coa...

Binaural Beat Stimulation Enhances Cognitive Function in Alzheimer’s Disease via Temporal Lobe Activation: An sLORETA Study

Background: The global prevalence of Alzheimer’s disease (AD) has reached 55.2 million. AD is characterized by progressive deterioration in cognition and working memory (WM), which are essential for attention, reasoning, and learning. These...

A physics-informed spatiotemporal graph neural network for photovoltaic power forecasting and micro-anomaly localization

Accurate power forecasting and precise fault diagnosis are critical for the reliable operation of large-scale photovoltaic systems. However, existing data-driven models often fail to capture complex spatiotemporal dependencies and lack phys...

Predictive digital twin for optimizing patient-specific radiotherapy regimens under uncertainty in high-grade gliomas

We develop a methodology to create data-driven predictive digital twins for optimal risk-aware clinical decision-making. We illustrate the methodology as an enabler for an anticipatory personalized treatment that accounts for uncertainties ...

Examination of medical students’ opinions on multimedia learning materials according to social cues: focusing on sound principles

Purpose Although interest in various forms of learning media is increasing due to the coronavirus disease 2019 (COVID-19) pandemic there is relatively little research on influencing student motivation by intervening in cognitive processing....

On scientific understanding with artificial intelligence

Molecular biology and integrated strategies for activating cryptic biosynthetic gene clusters toward next-generation antibiotic discovery

Antimicrobial resistance (AMR) has been identified as one of the 21st century’s severest global public health crises. AMR led to an estimated 4.95 million deaths in 2019 and will claim 10 million lives a year by 2050 in the absence of targe...

Association between myosteatosis and impaired glucose metabolism: A deep learning whole‐body magnetic resonance imaging population phenotyping approach

Abstract Background There is increasing evidence that myosteatosis, which is currently not assessed in clinical routine, plays an important role in risk estimation in individuals with impaired glucose metabolism, as it is associated with th...

Artificial Intelligence: A Modern Approach

Humankind has given itself the scientific name homo sapiens--man the wise--because our mental capacities are so important to our everyday lives and our sense of self. The field of artificial intelligence, or AI, attempts to understand intel...