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Academic Articles & Research Papers
Showing 20 of 1,732 academic articles
Pei-Lun Kuo, Ann Zenobia Moore, Frank R. Lin, Frank R. Lin et al. • Frontiers in Aging Neuroscience
(2021)
Objectives: Age-related hearing loss (ARHL) is highly prevalent among older adults, but the potential mechanisms and predictive markers for ARHL are lacking. Epigenetic age acceleration has been shown to be predictive of many age-associated...
DOAJ
Open Access (DOAJ)
DOI: 10.3389/fnagi.2021.790926
Kevin O. Murray, Sophia A. Mahoney, Ravinandan Venkatasubramanian, Douglas R. Seals et al. • Experimental Gerontology
(2023)
Age-associated cardiovascular (CV) dysfunction, namely arterial dysfunction, is a key antecedent to the development of CV disease (CVD). Arterial dysfunction with aging is characterized by impaired vascular endothelial function and stiffeni...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.exger.2023.112105
Hao Tang, Ting Qin, Zhiwen Yan, Changqing Li et al. • Frontiers in Neuroscience
(2026)
ObjectiveDioctyl terephthalate (DOTP), a widely used plasticizer in food packaging and environmental materials, has raised concerns regarding its potential impact on human health. This study aims to investigate the neurotoxicity-related mec...
DOAJ
Open Access (DOAJ)
DOI: 10.3389/fnins.2026.1783807
Gloria Metzner, Lukas Maximilian Horstmeier, Jürgen Bengel, Eva Maria Bitzer et al. • BMC Geriatrics
(2023)
Abstract Background In the aging population of Western societies, an increasing number of older adults have multiple chronic diseases. As multifaceted health problems imply the involvement of several healthcare professionals, multimorbid ol...
DOAJ
Open Access (DOAJ)
DOI: 10.1186/s12877-023-03797-2
Addisu Getie, Melaku Bimerew, Mihretie Gedfew, Baye Tsegaye Amlak et al. • Archives of Gerontology and Geriatrics Plus
(2025)
Introduction: Cognitive impairment is a medical condition caused by neurodegeneration, marked by a gradual decline in neurological, motor, psychological, and cognitive domain functions, as well as daily activities. It primarily affects indi...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.aggp.2025.100171
Francesco Valeri, Malena dos Santos Guilherme, Fuqian He, Nicolai M. Stoye et al. • Microorganisms
(2021)
Alzheimer’s disease is a progressive neurodegenerative disorder affecting around 30 million patients worldwide. The predominant sporadic variant remains enigmatic as the underlying cause has still not been identified. Since efficient therap...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/microorganisms9122548
Ralitsa Robeva, Georgi Kirilov, Dobromir Tanev, Analia Tomova et al. • Balkan Medical Journal
(2013)
Background: The neuroendocrine system is known to influence immunity, but the precise interactions between different hormones and autoimmune disorders remain obscure.
Aims: The present study aimed to investigate the role of daily serum ...
DOAJ
Open Access (DOAJ)
DOI: 10.5152/balkanmedj.2013.8064
Shiau-Fu Hsieh, Kuo-Liong Chien, Chu-Hao Weng, Yi-Ping Chiang • International Journal of Gerontology
(2017)
Background: The predictors for failure of home discharge after post-acute inpatient stroke rehabilitation need investigation.
Methods: With this retrospective case-control study conducted in a stroke rehabilitation unit in one tertiary hosp...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.ijge.2017.07.005
Xiang Tang, Guoqing Liu, Li Lin, Nong Xiao et al. • BMC Medical Genomics
(2023)
Abstract Background Neurodevelopmental disorder with absent language and variable seizures (NEDALVS, # 618707) are characterized by delayed speech and motor development, ocular abnormalities, and seizures. NEDAVLS is an autosomal dominant d...
DOAJ
Open Access (DOAJ)
DOI: 10.1186/s12920-023-01630-8
Liping Sun, Yang Yu, Beifang Niu, Beifang Niu et al. • Frontiers in Genetics
(2020)
The amount of erythrocyte-derived microRNAs (miRNAs) represents the majority of miRNAs expressed in whole blood. miR-451, miR-144, and miR-486, which are abundant in red blood cells (RBCs), are involved in the process of erythropoiesis and ...
DOAJ
Open Access (DOAJ)
DOI: 10.3389/fgene.2020.00442
Freiberg, Florentina Joyce, Kunstmann, Erdmute, König, Thomas, Matlach, Juliane et al. • GMS Ophthalmology Cases
(2016)
Background: To present a case of conjunctival lymphangioma in a girl with tuberous sclerosis complex.Methods/results: A 4-year-old girl presented with a relapsing cystic lesion of the bulbar conjunctiva in the right eye with string-of-pear...
DOAJ
Open Access (DOAJ)
DOI: 10.3205/oc000046
Scott Mastromatteo, Angela Chen, Jiafen Gong, Fan Lin et al. • HGG Advances
(2023)
Summary: Phasing of heterozygous alleles is critical for interpretation of cis-effects of disease-relevant variation. We sequenced 477 individuals with cystic fibrosis (CF) using linked-read sequencing, which display an average phase block ...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.xhgg.2022.100156
Wenjie Wu, Rongjing Xia, Si Ma, Zenglei Hu et al. • Poultry Science
(2026)
Newcastle disease (ND) caused by Newcastle disease virus (NDV) infection is a highly contagious avian disease that causes substantial threat to the global poultry industry. Emodin (EMO), a member of the free anthraquinone compounds derived ...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.psj.2026.107180
PMC: PMC13265661
Marina M Watowich, Rachel M Petersen, Layla Brassington, Audrey M Arner et al. • PLoS Genetics
(2026)
The apolipoprotein ε4 (APOE ε4) isoform directly alters cholesterol and immune biology and is associated with an increased risk of neurodegenerative and cardiometabolic disease in industrialized settings; nevertheless, APOE ε4-which is ance...
DOAJ
Open Access (DOAJ)
DOI: 10.1371/journal.pgen.1012285
Majed Alluqmani, Abdulfatah M. Alayoubi, Jamil A. Hashmi, Jamil A. Hashmi et al. • Frontiers in Genetics
(2024)
BackgroundVariants in a gene encoding sodium voltage-gated channel alpha subunit 1 (SCN1A) are known to cause a broad clinical spectrum of epilepsy and associated features, including Dravet syndrome (MIM 607208), non-Dravet developmental an...
DOAJ
Open Access (DOAJ)
DOI: 10.3389/fgene.2024.1496683
Auriemma Lauren B, Shah Shaili, Linden Lara M, Henriksen Melissa A • Epigenetics & Chromatin
(2012)
Abstract Background The tumor suppressor menin (MEN1) is mutated in the inherited disease multiple endocrine neoplasia type I, and has several documented cellular roles, including the activation and repression of transcription effected by s...
DOAJ
Open Access (DOAJ)
DOI: 10.1186/1756-8935-5-2
Mohammed Alyahya, Taghrid Aloraini, Youseef Al-Harbi, Lamia Alsubaie et al. • Journal of Biochemical and Clinical Genetics
(2022)
Background: Physicians and geneticists face challenges in making accurate diagnoses during clinical evaluations; affecting patients and clinicians. The aim of this study was to estimate the hit rate of the non-consanguineous population. Mor...
DOAJ
Open Access (DOAJ)
DOI: 10.24911/JBCGenetics/183-1664872492
Chun LUO, Yuyang HU, Bo SHU • Notulae Botanicae Horti Agrobotanici Cluj-Napoca
(2022)
Crown rot is one of the most destructive diseases of cultivated strawberry. The DOF family transcription factors, which involved in biotic stress, has not been studied in responding to strawberry crown rot. In this study, the DOFs of Fragar...
DOAJ
Open Access (DOAJ)
DOI: 10.15835/nbha50112640
Yuehua Yang, Fangkui Wang, Jialin Jiang, Ling Jiang • Agronomy
(2023)
Soil drench treatment using Paenibacillus polymyxa strain KN-03 was applied to citrus plants infected with Candidatus Liberibacter asiaticus (CLas). The infection status was assessed using PCR and a real-time quantitative PCR detection syst...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/agronomy13122958
Fengping Yan, Yuanyuan Chen, Xing Ye, Fu Zhang et al. • Diagnostic Pathology
(2021)
Abstract Background Sudden cardiac death (SCD) remains a great health threat and diagnostic challenge, especially those cases without positive autopsy findings. Molecular biomarkers have been urgently needed for the diagnosis of SCD display...
DOAJ
Open Access (DOAJ)
DOI: 10.1186/s13000-021-01127-x