Reset
Showing 20 of 1,863 academic articles

Impact of a Mobile App (LoAD Calc) on the Calculation of Maximum Safe Doses of Local Anesthetics: Protocol for a Randomized Controlled Trial

Pietro Elias Fubini, Georges Louis Savoldelli, Tal Sara Beckmann, Caroline Flora Samer et al. • JMIR Research Protocols (2024)

BackgroundLocal anesthetics (LAs) are regularly used to alleviate pain during medical or surgical procedures. Their use is generally considered safe, but exceeding the maximum recommended doses can lead to LA systemic toxicity, a rare but p...

DOAJ Open Access (DOAJ) DOI: 10.2196/53679

Early Retinal Microvascular Alterations in Young Type 1 Diabetic Patients without Clinical Retinopathy

Alexandra Oltea Dan, Alin Ștefănescu-Dima, Andrei Teodor Bălășoiu, Ileana Puiu et al. • Diagnostics (2023)

The purpose of this study is to identify and quantify preclinical changes with the help of optical coherence tomography angiography (OCTA) within the retinal microcirculation of young type 1 diabetes (T1D) patients without clinical signs of...

DOAJ Open Access (DOAJ) DOI: 10.3390/diagnostics13091648

Dataset on Women's empowerment, land and donor-driven agricultural interventions in Eastern Zambia

Progress H. Nyanga, Bridget Bwalya Umar, Douty Chibamba, Wilma S. Nchito • Data in Brief (2020)

A survey was conducted with 235 randomly selected households to investigate women's empowerment, land and donor-driven agricultural interventions in Eastern Zambia [1] for aid programmes with (Norwegian) and without (Chinese) women empowerm...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.dib.2020.106113

From Connectivity to Controllability: Unraveling the Brain Biomarkers of Major Depressive Disorder

Chunyu Pan, Ying Ma, Lifei Wang, Yan Zhang et al. • Brain Sciences (2024)

Major Depressive Disorder (MDD) is a significant neurological condition associated with aberrations in brain functional networks. Traditional studies have predominantly analyzed these from a network topology perspective. However, given the ...

DOAJ Open Access (DOAJ) DOI: 10.3390/brainsci14050509

A genome-wide association study on meat consumption in a Japanese population: the Japan Multi-Institutional Collaborative Cohort study

Yasuyuki Nakamura, Akira Narita, Yoichi Sutoh, Nahomi Imaeda et al. • Journal of Nutritional Science (2021)

Recent genome-wide association studies (GWAS) on the dietary habits of the Japanese population have shown that an effect rs671 allele was inversely associated with fish consumption, whereas it was directly associated with coffee consumption...

DOAJ Open Access (DOAJ) DOI: 10.1017/jns.2021.49

Modulation of frontal gamma oscillations improves working memory in schizophrenia

Fiza Singh, I-Wei Shu, Sheng-Hsiou Hsu, Peter Link et al. • NeuroImage: Clinical (2020)

Schizophrenia is a debilitating mental disorder that is associated with cognitive deficits. Impairments in cognition occur early in the course of illness and are associated with poor functional outcome, but have been difficult to treat with...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.nicl.2020.102339

The Association of Social Determinants of Health Screening With Developmental and Social-Emotional Outcomes in Children Enrolled in Head Start

Elizabeth K. Farkouh, Loren L. Toussaint, Brian A. Lynch • Journal of Primary Care & Community Health (2025)

Introduction/Objectives: Social determinants of health (SDOH) have the potential to differentially impact child developmental outcomes. This study examined whether scores on the Environmental Screening Questionnaire (ESQ), a newly developed...

DOAJ Open Access (DOAJ) DOI: 10.1177/21501319251384525

A Focus on Simulation in Medical Informatics

James G. Anderson • Journal of the American Medical Informatics Association (2002)

This special issue of JAMIA addresses simulation, a methodology that holds great promise for the advancement of information technology in health care. Simulation has been termed a third domain, complementing both natural language and mathem...

OPENALEX Open Access DOI: https://doi.org/10.1197/jamia.m1167 PMC: 346642

Effects of individualized rTMS on functional connectivity related to the default mode network and frontal-parietal network in major depressive disorder: exploratory analysis of a randomized controlled trial

Jing Jin, Yun Wang, Sixiang Liang, Qingchen Fan et al. • NeuroImage: Clinical (2025)

Objective: Repetitive transcranial magnetic stimulation (rTMS) has been shown to alleviate depressive and anxiety symptoms in patients with major depressive disorder (MDD), typically by targeting the dorsolateral (DLPFC) or dorsomedial pref...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.nicl.2025.103902

Central vein sign: A diagnostic biomarker in multiple sclerosis (CAVS-MS) study protocol for a prospective multicenter trial

D. Ontaneda, P. Sati, P. Raza, M. Kilbane et al. • NeuroImage: Clinical (2021)

The specificity and implementation of current MRI-based diagnostic criteria for multiple sclerosis (MS) are imperfect. Approximately 1 in 5 of individuals diagnosed with MS are eventually determined not to have the disease, with overrelianc...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.nicl.2021.102834

Evaluating an LLM-assisted workflow for clinical documentation: A pilot randomized controlled trial on time and quality.

Tomohiro Takayama, Keina Sado, Kenji Suda, Hiroshi Tamura et al. • PLOS Digital Health (2026)

Large language models (LLMs) have been investigated for clinical documentation, with concerns about hallucinations and factual errors. Clinician review and revision of LLM-generated drafts are considered essential; however, the impact of su...

DOAJ Open Access (DOAJ) DOI: 10.1371/journal.pdig.0001799

Requirements for Vitiligo Registry Design in Iran: A Qualitative Content Analysis Study

Zahra Arabkermani, Roxana Sharifian, Peivand Bastani, Azadeh Bashiri et al. • Journal of Health Sciences and Surveillance System (2025)

Background: Vitiligo is a prevalent skin disorder that has significant biological and social consequences for the affected individuals. Therefore, appropriate measures should be taken to diagnose this disease and treat patients, and powerfu...

DOAJ Open Access (DOAJ) DOI: 10.30476/jhsss.2024.101583.1884

The Effectiveness of Digital Therapeutics Intervention in Oral Anticoagulation Management: A Systematic Review and Meta-analysis

Jiayue Guo, MPH, Lili You, PhD, Lu Liu, MPH, Xitong Jiao, MPH et al. • Mayo Clinic Proceedings: Digital Health (2026)

Objective: To summarize the key intervention characteristics and evaluate the effectiveness and safety of digital therapeutics (DTx) in patients receiving oral anticoagulation, with effectiveness evaluated using time in therapeutic range (T...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.mcpdig.2026.100336

Combining Digital Cognitive Behavioral Therapy With Mindfulness Training for Binge Eating Disorder: Protocol for a Feasibility Trial

Margaret Sala, Corey Roos, Dante Ascarrunz, Casey M Stern et al. • JMIR Research Protocols (2026)

BackgroundCognitive behavioral therapy (CBT) is the most effective treatment for binge eating disorder (BED) but is limited by modest efficacy and low reach of in-person delivery. Combining mindfulness training with CBT could enhance effica...

DOAJ Open Access (DOAJ) DOI: 10.2196/91761

Grand Challenges in Medical Informatics?

Andrew Friede • Journal of the American Medical Informatics Association (1995)

Andrew Friede, MD, MPH; Grand Challenges in Medical Informatics?, Journal of the American Medical Informatics Association, Volume 2, Issue 2, 1 March 1995, Page...

OPENALEX Open Access DOI: https://doi.org/10.1136/jamia.1995.95261906 PMC: 116246

Is a prostate cancer screening anxiety measure invariant across two different samples of age-appropriate men?

Linder Suzanne K, Swank Paul R, Vernon Sally W, Morgan Robert O et al. • BMC Medical Informatics and Decision Making (2012)

Abstract Background In order to explore the influence of anxiety on decision–making processes, valid anxiety measures are needed. We evaluated a prostate cancer screening (PCS) anxiety scale that measures anxiety related to the prostate–spe...

DOAJ Open Access (DOAJ) DOI: 10.1186/1472-6947-12-52

Secondary research use of personal medical data: patient attitudes towards data donation

Gesine Richter, Christoph Borzikowsky, Bimba Franziska Hoyer, Matthias Laudes et al. • BMC Medical Ethics (2021)

Abstract Background The SARS-CoV-2 pandemic has highlighted once more the great need for comprehensive access to, and uncomplicated use of, pre-existing patient data for medical research. Enabling secondary research-use of patient-data is a...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12910-021-00728-x