Reset
Showing 20 of 1,262 academic articles

Cold storage of human precision-cut lung slices in TiProtec preserves cellular composition and transcriptional responses and enables on-demand mechanistic studies

M. Camila Melo-Narvaez, Fee Gölitz, Eshita Jain, Janine Gote-Schniering et al. • Respiratory Research (2025)

Abstract Background Human precision-cut lung slices (hPCLS) are a unique platform for functional, mechanistic, and drug discovery studies in the field of respiratory research. However, tissue availability, generation, and cultivation time r...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12931-025-03132-w

Advances in CAR T cell therapy: antigen selection, modifications, and current trials for solid tumors

Safwaan H. Khan, Safwaan H. Khan, Yeonjoo Choi, Mysore Veena et al. • Frontiers in Immunology (2025)

Chimeric antigen receptor (CAR) T cell therapy has revolutionized the treatment of hematologic malignancies, achieving remarkable clinical success with FDA-approved therapies targeting CD19 and BCMA. However, the extension of these successe...

DOAJ Open Access (DOAJ) DOI: 10.3389/fimmu.2024.1489827

Wild immunology

Amy B. Pedersen, Simon A. Babayan • Molecular Ecology (2011)

In wild populations, individuals are regularly exposed to a wide range of pathogens. In this context, organisms must elicit and regulate effective immune responses to protect their health while avoiding immunopathology. However, most of our...

OPENALEX DOI: https://doi.org/10.1111/j.1365-294x.2010.04938.x

Drought and Water Scarcity Management Policy in England and Wales—Current Failings and the Potential of Civic Innovation

Kevin Grecksch, Catharina Landström • Frontiers in Environmental Science (2021)

Drought management in England and Wales takes place in a narrow, confined governance space. Assessed against current literature on drought management, England and Wales show little innovativeness and little actual willingness to change. We ...

DOAJ Open Access (DOAJ) DOI: 10.3389/fenvs.2021.574975

Research on a Comprehensive Performance Analysis Method for Building-Integrated Photovoltaics Considering Global Climate Change

Ran Wang, Caibo Tang, Yuge Ma, Shilei Lu et al. • Buildings (2025)

Building-integrated photovoltaics (BIPVs) represent a pivotal technology for enhancing the utilization of renewable energy in buildings. However, challenges persist, including the lack of integrated design models, limited analytical dimensi...

DOAJ Open Access (DOAJ) DOI: 10.3390/buildings15244463

Nanomedicine for Glioblastoma: Cutting-Edge Advances and Persistent Challenges

Ladi Alik Kumar, K Sunand, Jitendra Debata, Gopal Krishna Padhy et al. • Journal of Bio-X Research (2025)

Cancer is a disorder characterized by the abnormal growth of cells that increases uncontrollably over an extended period of time. Treating cancerous brain tumors remains among the most challenging tasks for researchers, as brain tumors are ...

DOAJ Open Access (DOAJ) DOI: 10.34133/jbioxresearch.0065

<i>In-House</i> Innovative “Diamond Shaped” 3D Printed Microfluidic Devices for Lysozyme-Loaded Liposomes

Federica Sommonte, Edward Weaver, Essyrose Mathew, Nunzio Denora et al. • Pharmaceutics (2022)

Nanotechnology applications have emerged as one of the most actively researched areas in recent years. As a result, substantial study into nanoparticulate lipidic systems and liposomes (LPs) has been conducted. Regardless of the advantages,...

DOAJ Open Access (DOAJ) DOI: 10.3390/pharmaceutics14112484

GROWTH AND YIELD RESPONSES OF SOYBEAN (Glycine max L.) TO ZINC OXIDE (ZnO) NANOPARTICLES FOLIAR APPLICATION

Fayomi Omotola Michael, Olasan Joseph Olalekan, Aguoru Celestine Uzoma, Terhemba Mamnenge Sarah • Biotechnologia Acta (2024)

Aim. This study was purposed to investigate the effects of zinc oxide nanoparticles (ZnO NPs) on the growth and yield performance of two soybean (Glycine max L.) varieties, TGX1904-6F and TGX1951-3F, under controlled experimental conditions...

DOAJ Open Access (DOAJ) DOI: 10.15407/biotech17.06.056

Extracellular vesicles as circulating cancer biomarkers: opportunities and challenges

R. E. Lane, D. Korbie, M. M. Hill, M. Trau • Clinical and Translational Medicine (2018)

Abstract Extracellular vesicles (EVs) are small, lipid-bound particles containing nucleic acid and protein cargo which are excreted from cells under a variety of normal and pathological conditions. EVs have garnered substantial research int...

DOAJ Open Access (DOAJ) DOI: 10.1186/s40169-018-0192-7

Probiotics in Nanotechnology-Driven Wound Healing: From Mechanistic Insight to Clinical Promise

Milind Umekar, Anis Ahmad Chaudhary, Monali Manghani, Supriya Shidhaye et al. • Pharmaceutics (2025)

Chronic wounds, including diabetic foot ulcers and pressure sores, are becoming more prevalent due to aging populations and increased metabolic problems. These wounds often persist due to impaired healing, chronic inflammation, oxidative st...

DOAJ Open Access (DOAJ) DOI: 10.3390/pharmaceutics17070805

Nano-enabled microbial bioinputs for sustainable agriculture: advances, mechanisms, applications, and future challenges

Isadora Camargo Pedrino, Isadora Camargo Pedrino, Paulo Teixeira Lacava, Paulo Teixeira Lacava • Frontiers in Plant Science (2026)

Microbial bioinputs have emerged as key components of sustainable agriculture owing to their ability to promote plant growth, improve nutrient acquisition, enhance tolerance to biotic and abiotic stresses, and suppress phytopathogens. Despi...

DOAJ Open Access (DOAJ) DOI: 10.3389/fpls.2026.1925672

Achieving high strength in 430 stainless steel by laser powder bed fusion: microstructure-property relationships and strengthening strategies

Junchen Li, Qiushuang Wang, Swee Leong Sing, Congwei Wang et al. • Virtual and Physical Prototyping (2026)

Conventional manufacturing of 430 ferritic stainless steel faces significant challenges, including severe work hardening, rapid tool wear, and limited strengthening via heat treatment. To overcome these limitations, this study employs laser...

DOAJ Open Access (DOAJ) DOI: 10.1080/17452759.2026.2631285

Manufacturing of Hierarchical (Nano-)Composite Structures: Numerical and Experimental Perspectives

Hatim Alotaibi, Constantinos Soutis, Masoud Jabbari • Applied Sciences (2026)

Thermoset polymer nanocomposites have considerable potential to improve the functionality and optimise the performance of composite structures. Such a nanocomposite generally consists of a modified polymer matrix (continuous phase) containi...

DOAJ Open Access (DOAJ) DOI: 10.3390/app162010379

Small cell neuroendocrine carcinoma of the cervix: From molecular basis to therapeutic advances

Angel Chao, Ren-Chin Wu, Chiao-Yun Lin, Ting-Chang Chang et al. • Biomedical Journal (2023)

Small cell neuroendocrine carcinoma of the cervix (SCNECC) is an uncommon but aggressive uterine malignancy, the cause of which is generally associated with human papillomavirus (HPV) infection. A lack of clinical trials and evidence-based ...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.bj.2023.100633

Applications and insights from continuous dengue virus infection in a stable cell line

M. Jane Morwitzer, Ying Yi Zheng, Heather Friberg, Jeffrey R. Currier • Frontiers in Immunology (2025)

Dengue is caused by the four serotypes of dengue virus (DENV-1-4) and poses a significant global public health challenge, with an estimated 100–400 million infections annually. Severe dengue manifestations, such as Dengue Hemorrhagic Fever ...

DOAJ Open Access (DOAJ) DOI: 10.3389/fimmu.2025.1618650

Technology-Supported Behavior Change—Applying Design Thinking to mHealth Application Development

Ramona Schweitzer, Stephan Schlögl, Marco Schweitzer • European Journal of Investigation in Health, Psychology and Education (2024)

Non-communicable diseases are the leading cause of global deaths. The risk of their development and progression is increased by modifiable behavioral risk factors. Yet, despite the known benefits of primary and secondary prevention, people ...

DOAJ Open Access (DOAJ) DOI: 10.3390/ejihpe14030039

Approaches, challenges, and recommendations for clinical practice in gestational syphilis: a scoping review

Camila Rocha Silveira, Franciela Delazeri Carlotto, Luísa Amanda Krüger, Giulia Chaves Seter et al. • Revista Gaúcha de Enfermagem (2026)

ABSTRACT Objective to map the scientific evidence on the approach to gestational syphilis, the sociodemographic profile of pregnant women, and the challenges related to its management and follow-up. Method scoping review carried out in Oc...

DOAJ Open Access (DOAJ) DOI: 10.1590/1983-1447.2026.20250374.en