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Analysis of Cathinone Alkaloids in Khat by HPLC-Q-TOF In-source Fragmentation Multistage Mass Spectrometry

SHI Hong-fei1, XU Bo-peng1, QUAN Yang-ke2, XU Cheng-xin1, ZHOU Xiu-qi1 • Zhipu Xuebao (2024)

Khat is a kind of common drug plant. Many experiments have shown that the content of cathinone norpseudoephedrine and norephedrine in some varieties of Khat are similar. However, some studies showed that there are differences in the intensi...

DOAJ Open Access (DOAJ) DOI: 10.7538/zpxb.2023.0065

A Coarse-to-Fine Approach for Rectifying Distorted Latent Fingerprints From Crime Scenes

Qing Bao, Ya-Gang Wang, Chang Gao, Liangxiao Sha et al. • IEEE Access (2023)

With the widely used fingerprints to identify criminals, the influence of fingerprint deformation arouses attention in forensic science. To date, many approaches have been proposed to rectify distorted fingerprints. However, the performance...

DOAJ Open Access (DOAJ) DOI: 10.1109/ACCESS.2023.3344465

Forensic Application of Next Generation Sequencing Technology in the Typing of Y Chromosome Genetic Marker

YANG Yue , TAO Rui-yang , LI Min , et al. • Fayixue Zazhi (2021)

The paternal inheritance characteristics of Y chromosome have been widely used in the forensic genetics field to detect the genetic markers in the non-recombining block, and used in the studies such as, genetic relationship identification, ...

DOAJ Open Access (DOAJ) DOI: 10.12116/j.issn.1004-5619.2020.501205

Genome-based development of 15 microsatellite markers in fluorescent multiplexes for parentage testing in captive tigers

Xiao Zhao, Qiguan Qiu, Chang Li, Dongke Fu et al. • PeerJ (2020)

As one of the most endangered species, tiger (Panthera tigris) inbreeding has become an urgent issue to address. Using a microsatellite (short tandem repeat, STR) identification system, paternity testing may be helpful to avoid inbreeding i...

DOAJ Open Access (DOAJ) DOI: 10.7717/peerj.8939

Bacterial Succession in Microbial Biofilm as a Potential Indicator for Postmortem Submersion Interval Estimation

Finkelbergs Dmitrijs, Juanjuan Guo, Juanjuan Guo, Juanjuan Guo et al. • Frontiers in Microbiology (2022)

Bacteria acts as the main decomposer during the process of biodegradation by microbial communities in the ecosystem. Numerous studies have revealed the bacterial succession patterns during carcass decomposition in the terrestrial setting. T...

DOAJ Open Access (DOAJ) DOI: 10.3389/fmicb.2022.951707

Optimization of Bacillus cereus Fermentation Process for Selenium Enrichment as Organic Selenium Source

Xujun Chen, Shuyi Li, Xin Cong, Xin Cong et al. • Frontiers in Nutrition (2020)

Selenium is an essential trace element and micronutrient for human health. Application of organic selenium in plants and microorganisms as trace element supplement is attracting more and more attention. In this study, Bacillus cereus, an im...

DOAJ Open Access (DOAJ) DOI: 10.3389/fnut.2020.543873

UPLC-MS/MS Metabolomics Reveals Babao Dan’s Mechanisms in MASH Treatment with Integrating Network Pharmacology and Molecular Docking

Shijiao Zhang, Yanding Su, Ao Han, He Qi et al. • Pharmaceuticals (2025)

Background: Metabolic dysfunction-associated steatohepatitis (MASH) is a progressive disease that easily develops into cirrhosis and hepatocellular carcinoma, but its pathogenesis is not clear, and most therapeutic drugs have obvious limita...

DOAJ Open Access (DOAJ) DOI: 10.3390/ph18081111

The features analysis of hemoglobin expression on visual information transmission pathway in early stage of Alzheimer’s disease

Xuehui Li, Pan Tang, Xinping Pang, Xianghu Song et al. • Scientific Reports (2024)

Abstract Alzheimer's disease (AD) is a neurodegenerative disorder characterized primarily by cognitive impairment. The motivation of this paper is to explore the impact of the visual information transmission pathway (V–H pathway) on AD, and...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-024-64099-0

Impact of Pressurized Liquid Extraction and pH on Protein Yield, Changes in Molecular Size Distribution and Antioxidant Compounds Recovery from Spirulina

Jianjun Zhou, Min Wang, Celia Carrillo, Zhenzhou Zhu et al. • Foods (2021)

The research aims to extract nutrients and bioactive compounds from spirulina using a non-toxic, environmentally friendly and efficient method—Pressurized Liquid Extraction (PLE). In this work, Response Surface Methodology (RSM)–Central Com...

DOAJ Open Access (DOAJ) DOI: 10.3390/foods10092153

Alterations in the gut microbiota and its metabolites contribute to metabolic maladaptation in dairy cows during the development of hyperketonemia

Zhengzhong Luo, Zhenlong Du, Yixin Huang, Tao Zhou et al. • mSystems (2024)

ABSTRACTMetabolic maladaptation in dairy cows after calving can lead to long-term elevation of ketones, such as β-hydroxybutyrate (BHB), representing the condition known as hyperketonemia, which greatly influences the health and production ...

DOAJ Open Access (DOAJ) DOI: 10.1128/msystems.00023-24

Herb-drug interactions of silybinin and cilofexor in beagle dogs based on pharmacokinetics by UPLC-MS/MS

Xinyi Wei, Yanding Su, Qian Cheng, Songmao Liang et al. • Frontiers in Pharmacology (2024)

Objective: A remarkably sensitive, accurate, and efficient ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) approach was developed as a facile and expeditious method for measuring cilofexor concentration in beag...

DOAJ Open Access (DOAJ) DOI: 10.3389/fphar.2024.1334402

GPR55 activation improves anxiety- and depression-like behaviors of mice during methamphetamine withdrawal

Jinlong Zhang, Jie Yan, Shuyue Li, Qianqian Chen et al. • Heliyon (2024)

Methamphetamine is a potent and highly addictive neurotoxic psychostimulant that triggers a spectrum of adverse emotional responses during withdrawal. G-protein coupled receptor 55 (GPR55), a novel endocannabinoid receptor, is closely assoc...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.heliyon.2024.e30462

The Effect of Yinchenhao Decoction on the Pharmacokinetic Profile of Futibatinib by HPLC-MS/MS

Chunfu Wang, Songmao Liang, Jiachen Xu, Yingfan Zhai et al. • Separations (2024)

Futibatinib is an excellent fibroblast growth factor receptor 1–4 (FGFR 1–4) inhibitor that exhibits selective anti-tumor activeness against FGFR-deregulated tumors. A new high-performance liquid chromatography-tandem mass spectrometry (HPL...

DOAJ Open Access (DOAJ) DOI: 10.3390/separations11070213

Effect of Theaflavins-Soy Protein Isolate Complex Coating on the Quality of Lentinus edodes

Yu WANG, Peiyue ZHAO, Shicheng LEI, Yiyan YANG et al. • Shipin gongye ke-ji (2023)

In order to clarify the preservation effect of theaflavins-soy protein isolate complex coating on Lentinus edodes, a TFs-SPI complex coating agent was prepared by mixing theaflavins and soy protein isolate as subjects, and its structure was...

DOAJ Open Access (DOAJ) DOI: 10.13386/j.issn1002-0306.2022070074

Methyl Jasmonate and Zinc Sulfate Induce Secondary Metabolism and Phenolic Acid Biosynthesis in Barley Seedlings

Xin Tian, Renjiao Zhang, Zhengfei Yang, Weiming Fang • Plants (2024)

This study aimed to reveal the impact of MeJA and ZnSO4 treatments on the physiological metabolism of barley seedlings and the content of phenolic acid. The results showed that MeJA (100 μM) and ZnSO4 (4 mM) treatments effectively increased...

DOAJ Open Access (DOAJ) DOI: 10.3390/plants13111512

Chemical Diversity of Fuzhuan Brick Teas from Hunan and Shaanxi

ZHANG Ning, YU Shilan, YAN Haoyi, ZHANG Yunjun, HAN Xiaoyu, REN Hongyu, CHEN Yuqing, LING Tiejun, AN Maoqiang • Shipin Kexue (2024)

This study aimed to explore the diversity of metabolites and compare the metabolite profiles of Fuzhuan brick teas from Hunan and Shaanxi, to find out the difference in chemical components between fresh tea leaves and Fuzhuan brick tea and ...

DOAJ Open Access (DOAJ) DOI: 10.7506/spkx1002-6630-20231108-066

Explore the effects of forest travel activities on university students’ stress affection

Wei-Yin Chang, Xin Wang, De-Sheng Guo, Lam-Huu-Phuoc Nguyen et al. • Frontiers in Psychology (2024)

This study aims to explore the effects of forest travel activities on university students’ stress affection. Forty volunteer university students participated in this study. All participants were asked to complete physiological (Heart Rate V...

DOAJ Open Access (DOAJ) DOI: 10.3389/fpsyg.2023.1240499